Results 241 to 250 of about 200,124 (304)

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

The link between macrophage polarization and response to radiotherapy in cancers: mechanisms and therapeutic opportunities. [PDF]

Front Immunol
Zhao Z, Zheng Z.
europepmc   +1 more source

The pentose phosphate pathway contributes to excess lactate production in radiation-induced fibroblast to myofibroblast transdifferentiation. [PDF]

J Biol Chem
Pierre-Louis Odoom J, Camus SV, Sfeir M, Yue Y, Cowart LA, Freeberg MAT, Thatcher TH, Sime PJ.   +7 more
europepmc   +1 more source

PTPRE promotes gastric cancer cell resistance to 5-fluorouracil by inhibiting ferroptosis via the Src/FAK/TRIB3 axis. [PDF]

PLoS One
Liu M, Liao X, Wang F, Jiao P, Wang Z.
europepmc   +1 more source

IFN signaling at the nexus of the radiotherapy response in malignant peripheral nerve sheath tumors. [PDF]

J Clin Invest
Pitroda SP, Weichselbaum RR.
europepmc   +1 more source

Chronic Radiation Dermatitis After Breast Cancer Radiotherapy: Mechanistic Insights, Therapeutic Challenges, and Emerging Roles of Piezo1-Mediated Mechanotransduction. [PDF]

J Inflamm Res
Wang Z, Chen F, Li Z.
europepmc   +1 more source

Tumor response and tolerability under fractionated x-ray irradiation in a mouse xenograft model. [PDF]

Phys Med Biol
Choi K, Szu J, Camara Serrano JA, Steri V, Gunther C, Seo Y, Peter R.   +6 more
europepmc   +1 more source

[2 cases of using the greater omentum in the treatment of radiation-induced chest lesions in breast neoplasms].

Nowotwory, 1978
openaire   +1 more source