CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis [PDF]
Retinoblastoma is a pediatric eye tumor in which bi-allelic inactivation of the Retinoblastoma 1 (RB1) gene is the initiating genetic lesion. Although recently curative rates of retinoblastoma have increased, there are at this time no molecular targeted ...
Boel, Annekatrien +12 more
core +2 more sources
Liver Resection for Primary Hepatic Neoplasms. [PDF]
Subtotal hepatic resection was performed in 356 patients; 87 had primary hepatic malignancies, 108 had metastatic tumors, and 161 had benign lesions including 8 traumatic injuries. The global mortality was 4.2%.
C. Couinaud +16 more
core +1 more source
Radiation-Induced Undifferentiated Pleomorphic Sarcoma after Breast Conserving Therapy: Case Report
Introduction: Breast sarcoma is a rare form of malignancy that arises from connective tissue, comprising less than 5% of all sarcomas. Undifferentiated pleomorphic sarcoma (UPS) of the breast is a rare and aggressive subtype of radiation-induced sarcoma
Tainara Rodrigues Miranda +4 more
doaj +1 more source
Second primary malignancies of eye and ocular adnexa after a first primary elsewhere in the body
Purpose The eye and its adnexal structures can give rise to first or consecutive primary malignancies or to encounter metastasis. Our aim was to define the characteristics of the second primary neoplasms affecting the eye and its adnexa and find the risk
Ahmad Samir Alfaar +5 more
semanticscholar +1 more source
No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Burmeister, Thomas +4 more
core +2 more sources
Metachronous Adenoid Cystic Carcinoma in the Peripheral Lung and at Base of the Tongue [PDF]
Primary lung adenoid cystic carcinoma (ACC) is extremely rare and accounts for approximately 0.1%-0.2% of all lung cancers. ACC of the head and neck has generally been regarded as a slow-growing, low-grade malignancy which has a tendency for local ...
Jun Hyun Kim +3 more
doaj +1 more source
Emerging targets in human lymphoma: targeting the MYD88 mutation [PDF]
B cell neoplasms co-opt the molecular machinery of normal B cells for their survival. Technological advances in cancer genomics has significantly contributed to uncovering the root cause of aggressive lymphomas, revealing a previously unknown link ...
Horikawa, Keisuke +2 more
core +1 more source
Incidentally Diagnosed Breast Cancer in a Patient with Rectal Cancer: A Case Report [PDF]
The development of screening and therapeutic approaches has improved the prognosis of colorectal cancer(CRC) patients, leading to an expected increase in the incidence of second primary cancers (SPCs).
Marzieh Rahimi +7 more
doaj +1 more source
Impact of primary site on survival in patients with nasopharyngeal carcinoma from 2004 to 2015
BackgroundNasopharynx carcinoma (NPC) is the most common malignant tumor of the nasopharynx. Many studies have shown some factors related with the prognosis of NPC patients.
Tianyi Shen +6 more
doaj +1 more source
Metallopanstimulin as a marker for head and neck cancer [PDF]
BACKGROUND: Metallopanstimulin (MPS-1) is a ribosomal protein that is found in elevated amounts in the sera of patients with head and neck squamous cell carcinoma (HNSCC).
A Agrawal +28 more
core +4 more sources

