Results 131 to 140 of about 1,891,938 (317)

Significance of GRP78 expression in acute myeloid leukemias

Open Medicine, 2014
Wróbel Tomasz, Stefanko Ewa, Dzietczenia Justyna, Jaźwiec Bożena, Mazur Grzegorz, Haus Olga, Dybko Jarosław, Kuliczkowski Kazimierz   +7 more
doaj   +1 more source

P980: THE ROLE OF PLATELET AND ENDOTHELIAL MICROPARTICLES AND DOPPLER ULTRASOUND SCREENING IN THE ASSESSMENT OF THROMBOTIC READINESS IN MULTIPLE MYELOMA AND NON HODGKIN LYMPHOMA, PROSPECTIVE STUDY

HemaSphere, 2023
Magdalena Olszewska-Szopa, Urszula Zaleska-Dorobisz, Agnieszka Zubkiewicz-Kucharska, Iwona Prajs, Tomasz Wróbel, Lidia Usnarska-Zubkiewicz   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Primary pancreatic cystic neoplasms of the pancreas revisited. Part IV: Rare cystic neoplasms [PDF]

, 2012
Primary pancreatic cystic neoplasms are being recognized with increasing frequency due to modern imaging techniques. In addition to the more common cystic neoplasms - serous cystadenoma, primary mucinous cystic neoplasm, and intraductal papillary ...
Smyrniotis, V., Sakorafas, G.H., Reid-Lombardo, K.M., Sarr, M.G.   +3 more
core  

Ascites in the Course of Plasma Cell Myeloma Complicated by AL Amyloidosis

Turkish Journal of Hematology, 2018
Jakub Debski, Lidia Usnarska - Zubkiewicz, Katarzyna Kapelko- Slowik, Aleksander Pawlus, Urszula Zaleska - Dorobisz, Kazimierz Kuliczkowski   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

UDC: 616.681-006:615.38:616-06 DOI: 10.2298/AOO0902025G [PDF]

, 2014
Testicular neoplasms metastasizing to the retroperitoneum rarely involve the upper gastrointestinal tract. We describe an unusual case of contained small bowel perforation as a complication of chemotherapy treatment of metastatic non seminomatous germ ...
Ehab Helmy, Vojvodina Sremska Kamenica, Abdel Goad, Testicular Neoplasms Neoplasms, Germ Cell, Arch Oncol, Metastasis Retroperitoneal Neoplasms, Key Words, Embryonal Neoplasm   +8 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

The molecular pathogenesis of myeloproliferative neoplasms [PDF]

, 2010
Myeloproliferative neoplasms (MPNs) are a heterogeneous group of haematological stem cellmalignancies characterised by proliferation of one or more cells of the myeloid lineage.
Jones, Amy Victoria
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