Results 171 to 180 of about 2,036,299 (361)

Surgical methods of absorption of soft tissue defects after removal of benign neoplasms of the parotid gland

, 2022
T Z Chkadua, Z Yu Visaitova, N V Vereshchagina   +2 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Are thrombosis, progression, and survival in ET predictable?

Blood Cancer Journal
Ghaith Abu-Zeinah, Katie Erdos, Neville Lee, Ahamed Lebbe, Imane Bouhali, Mohammed Khalid, Richard T. Silver, Joseph M. Scandura   +7 more
doaj   +1 more source

Coronary artery bypass grafting in patients with hematological neoplasms. [PDF]

Front Cardiovasc Med
Zhang L, Zhang S, Jiang H, Liu J, Gao Q, Lian B, Liu Z, Shi Y.   +7 more
europepmc   +1 more source

87P Enhancing treatment strategies for metastatic high-grade neuroendocrine neoplasms: Insights from extensive genomic profiling through WES and WGS in a phase I clinical setting [PDF]

S.K. Krogshede, Ida Kappel Buhl, Louis J. Perino, Christian Baudet, Christina W. Yde, Malene Martini Clausen, Ida Elisabeth Viller Tuxen, Martin Hoejgaard, Seppo W. Langer, Iben Spanggaard, Kristoffer Staal Rohrberg   +10 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Evaluation of the 2015 AGA guidelines on pancreatic cystic neoplasms in a large surgically confirmed multicenter cohort [PDF]

, 2017
Early, Dayna S, et al.,, Gaddam, Srinivas, Kushnir, Vladimir M, Mullady, Daniel   +4 more
core   +2 more sources

C030 | GENOTYPE-PHENOTYPE CORRELATES AND OUTCOMES OF EXTRAMEDULLARY ACUTE MYELOID LEUKEMIA

Haematologica
Background: Genomic abnormalities associated with extramedullary (EM) acute myeloid leukemia (eAML) and their impact on clinical outcomes are not well understood since previous studies were limited to small case series with controversial results.
G.G. Loscocco, F. Mannelli, M. Piccini, B. Scappini, F. Crupi, G. Ciolli, L. Fasano, G. Rotunno, F. Pancani, C. Maccari, L. Signori, P. Guglielmelli, A.M. Vannucchi   +12 more
doaj  

Clinical-laboratory, therapeutic and survival profile of patients with low-risk Myelodysplastic Neoplasm in southern Brazil [PDF]

C. Weber, Tahiane de Brum Soares
openalex   +1 more source

Treatment-free remission in FIP1L1-PDGFRA–positive myeloid/lymphoid neoplasms with eosinophilia after imatinib discontinuation [PDF]

, 2020
Georgia Metzgeroth, Juliana Schwaab, Nicole Naumann, Mohamad Jawhar, Torsten Haferlach, Alice Fabarius, Andreas Hochhaus, Wolf‐Karsten Hofmann, Nicholas C.P. Cross, Andreas Reiter   +9 more
openalex   +1 more source