CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan+6 more
wiley +1 more source
Characteristics of Superficial Gastric Neoplasms Detected Not by White Light Imaging but by Linked Color Imaging. [PDF]
Yamaoka M+8 more
europepmc +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Examining associations of digestive system cancer with hypertension and diabetes using network analysis in older patients. [PDF]
Hashimoto H+6 more
europepmc +1 more source
Are thrombosis, progression, and survival in ET predictable?
Ghaith Abu-Zeinah+7 more
doaj +1 more source
Spontaneous neoplasms in fishes. I. Osteochondroma in the jewelfish, Hemichromis bimaculatus
Ross F. Nigrelli, Myron Gordon
openalex +1 more source
Malignant neoplasms of the nose, illustrated by a specimen of cylindroma [PDF]
openalex +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Ulcerative colitis-associated colorectal neoplasm is increasing as a surgical indication in the biologics era: a retrospective observational study of 20 years of experience in a single tertiary center. [PDF]
Kim HJ+7 more
europepmc +1 more source