Results 221 to 230 of about 1,398,433 (359)

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Gut microbiome in gastrointestinal neoplasms: from mechanisms to precision therapeutic strategies. [PDF]

Gut Pathog
Song J, Zhang W, Wang D.
europepmc   +1 more source

Myeloproliferative neoplasms

HemaSphere, 2019
openaire   +3 more sources

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Case Illustrating Recent Radical Operation for Testicular Neoplasm [PDF]

, 1933
C. Hope Carlton
openalex   +1 more source

Mucinous cystic neoplasms of the pancreas and liver share a similar DNA methylation profile with mucinous ovarian tumors. [PDF]

J Pathol
Leoni Z, Calina TG, Janik T, Grafenhorst E, Taube ET, Neumann CC, Chen B, Braicu EI, Sehouli J, Malinka T, Schöning W, Pratschke J, Calin GA, Klimstra DS, Benhamida JK, Esposito I, Möbs M, Horst D, Schallenberg S, Capper D, Dragomir MP.   +20 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Targeting CBP revers chemoresistance to 5‐FU of CDX2/REG4 double‐positive gastric cancer

Clinical and Translational Medicine
Zhiyuan Fan, Fangyuan Li, Xiao Jiang, Tao Pan, Mingde Zang, Jianfang Li, Beiqin Yu, Qingqing Sang, Wentao Liu, Liping Su, Chen Li, Zhenggang Zhu, Min Yan, Chao Yan, Fei Yuan, Bingya Liu   +15 more
doaj   +1 more source

Bronchogenic Neoplasms [PDF]

, 1939
Henry D. Rentschler, J. Chalmers Bryson
openalex   +1 more source

Clinical Significance of TP53-Mutant Clonal Hematopoiesis Across Diseases. [PDF]

Blood Cancer Discov
Usui Y, Endo M, Iwasaki Y, Iijima H, Nakagawa H, Matsuda K, Momozawa Y.   +6 more
europepmc   +1 more source