Results 231 to 240 of about 2,212,728 (310)

Subset‐specific and tissue‐specific expression of NK‐cell markers and killer immunoglobulin‐like receptors: Implications for NK‐cell clonality assessment

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate immunophenotypic evaluation of natural killer (NK)‐cell neoplasms is challenging because NK‐cells lack somatically rearranged antigen receptors, are comprised of phenotypically distinct subsets, and exhibit tissue‐specific subset distribution. We developed a flow cytometry (FC) panel for NK‐cell immunophenotypic analysis and clonality
Valerie Woodings   +7 more
wiley   +1 more source

Clinical applications of CD34+ progenitor cell immunophenotyping in myelodysplastic neoplasms—The CytHem SMD French network experience

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Myelodysplastic neoplasms (MDS) are clonal hematopoietic disorders characterized by ineffective hematopoiesis, peripheral cytopenias, and a risk of progression to acute myeloid leukemia. As the disease originates in hematopoietic stem and progenitor cells (HSPCs), flow cytometry (FCM) has emerged as a key approach to interrogate the bone ...
Nicolas Chapuis   +5 more
wiley   +1 more source

Comparison of EBER flow FISH results from two facilities

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Epstein–Barr virus (EBV) primarily infects B cells but can occasionally target T and/or NK cells, leading to chronic active EBV disease or EBV‐associated hemophagocytic lymphohistiocytosis, which are often difficult to treat. EBV‐associated diseases exhibit a wide range of phenotypes.
Madoka Nishimura   +13 more
wiley   +1 more source

Artificial intelligence‐based screening of paroxysmal nocturnal hemoglobinuria clones: Development and comparative evaluation of machine learning models

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract The diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) relies on detecting cells deficient in GPI‐anchored proteins and is currently based on manual, time‐consuming interpretation requiring specialized expertise. This study aimed to develop machine learning models to identify PNH clones in granulocytes and monocytes using flow cytometry ...
Felipe Magalhães Furtado   +5 more
wiley   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

FoxP3+ Regulatory T-Cells in Canine Cutaneous Lymphoma and Their Role in Immune Modulation. [PDF]

open access: yesIn Vivo
Semolin LMS   +10 more
europepmc   +1 more source

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