Results 1 to 10 of about 816,794 (268)

Absence of a dose-rate effect in the transformation of C3H 10T1/2 cells by α-particles [PDF]

open access: yes, 1987
The findings of Hill et al. (1984) on the greatly enhanced transformation frequencies at very low dose rates of fission neutrons induced us to perform an analogous study with -particles at comparable dose rates. Transformation frequencies were determined
Fenn, S.   +5 more
core   +1 more source

Tomato protoplast DNA transformation: physical linkage and recombination of exogenous DNA sequences [PDF]

open access: yes, 1987
Tomato protoplasts have been transformed with plasmid DNA's, containing a chimeric kanamycin resistance gene and putative tomato origins of replication.
Zabel, Pim   +11 more
core   +1 more source

Mechanisms of Radiation Toxicity in Transformed and Non-Transformed Cells [PDF]

open access: yesInternational Journal of Molecular Sciences, 2013
Radiation damage to biological systems is determined by the type of radiation, the total dosage of exposure, the dose rate, and the region of the body exposed. Three modes of cell death—necrosis, apoptosis, and autophagy—as well as accelerated senescence have been demonstrated to occur in vitro and in vivo in response to radiation in cancer cells as ...
Panganiban, Ronald-Allan M.   +2 more
openaire   +2 more sources

Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes [PDF]

open access: yes, 2009
In normal T cell progenitors, phosphoinositide-dependent kinase l (PDK1)-mediated phosphorylation and activation of protein kinase B (PKB) is essential for the phosphorylation and inactivation of Foxo family transcription factors, and also controls T ...
Feijoo, C.   +20 more
core   +1 more source

Cell transformation assays for prediction of carcinogenic potential: State of the science and future research needs

open access: yes, 2011
Copyright @ 2011 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use ...
R. R. Shen   +31 more
core   +1 more source

PEG-mediated and Agrobacterium-mediated transformation in the mycopathogen Verticillium fungicola [PDF]

open access: yes, 2002
Verticillium fungicola, a severe mycopathogen of the cultivated mushroom Agaricus bisporus, was successfully transformed using both PEG-mediated and Agrobacterium-mediated techniques.
Bailey, Andy M.   +11 more
core   +1 more source

Basic methodology for cell culture--cell transformation

open access: yes, 1974
The word "transformation" is used to describe the permanent acquisition of new characters by cultured cells. Of the many different types of transformation that are known, the best studied is neoplastic transformation.
Joseph Sambrook   +5 more
core   +1 more source

Efficient sweet pepper transformation mediated by the BABY BOOM transcription factor

open access: yes, 2011
Pepper (Capsicum L.) is a nutritionally and economically important crop that is cultivated throughout the world as a vegetable, condiment, and food additive.
Boutilier, K.   +10 more
core   +1 more source

Tumour-stromal interactions: Integrins and cell adhesions as modulators of mammary cell survival and transformation

open access: yes, 2001
Stromal–epithelial interactions modulate mammary epithelial cell (MEC) growth and apoptosis by influencing cell adhesion and tissue organization. Perturbations in the mammary stroma and cell adhesion characterize breast tumors and underlie the altered ...
Chrenek, Micah A.   +2 more
core   +1 more source

Notch and Schwann cell transformation [PDF]

open access: yesOncogene, 2004
Benign plexiform neurofibromas in NF1 patients can transform spontaneously into malignant peripheral nerve sheath tumors (MPNSTs). Although mutations in the p53 gene have been found in a subset of MPNSTs and mouse models support a role for p53 mutations in malignant conversion, we found that each of three Schwann cell lines derived from human MPNSTs ...
Yiwen, Li   +8 more
openaire   +2 more sources

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