Absence of a dose-rate effect in the transformation of C3H 10T1/2 cells by α-particles [PDF]
The findings of Hill et al. (1984) on the greatly enhanced transformation frequencies at very low dose rates of fission neutrons induced us to perform an analogous study with -particles at comparable dose rates. Transformation frequencies were determined
Fenn, S. +5 more
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Cell transformation assays for prediction of carcinogenic potential: State of the science and future research needs [PDF]
Copyright @ 2011 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use ...
R. R. Shen +31 more
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Tumour-stromal interactions: Integrins and cell adhesions as modulators of mammary cell survival and transformation [PDF]
Stromal–epithelial interactions modulate mammary epithelial cell (MEC) growth and apoptosis by influencing cell adhesion and tissue organization. Perturbations in the mammary stroma and cell adhesion characterize breast tumors and underlie the altered ...
Chrenek, Micah A. +2 more
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Efficient sweet pepper transformation mediated by the BABY BOOM transcription factor [PDF]
Pepper (Capsicum L.) is a nutritionally and economically important crop that is cultivated throughout the world as a vegetable, condiment, and food additive.
Boutilier, K. +9 more
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Basic methodology for cell culture--cell transformation [PDF]
The word "transformation" is used to describe the permanent acquisition of new characters by cultured cells. Of the many different types of transformation that are known, the best studied is neoplastic transformation.
Joseph Sambrook +5 more
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The impact of molecular alterations and the immune microenvironment on the natural history of Follicular Lymphoma including transformation to Diffuse Large B cell Lymphoma [PDF]
PhDThe natural history of follicular lymphoma is heterogeneous with numerous relapses and remissions over many years. A substantial number of patients suffer an aggressive disease course with death due to disease within 5 years of diagnosis.
Lee, Abigail Mary
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Control of the EBV growth transformation programme: the importance of the Bamhi W repeats [PDF]
Epstein-Barr virus (EBV), a human gammaherpesvirus, possesses a unique set of latent genes whose constitutive expression in B cells leads to cell growth transformation.
Kao, Kuan-Yu
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Histologic Transformation in an EGFR-Mutant Lung Cancer in a Filipino Patient treated with Afatinib
We report a case of a 64-year-old Filipino male who initially presented with chronic cough, easy fatigability, and weight loss. Work-ups lead to a diagnosis of lung adenocarcinoma with epidermal growth factor receptor (EGFR) exon 19 deletion. Patient was
Steffanie Charlyne Tamayo +6 more
doaj +1 more source
Cadmium (Cd) is a widespread environmental pollutant and carcinogen. Although the exact mechanisms of Cd-induced carcinogenesis remain unclear, previous acute/chronic Cd exposure studies have shown that Cd exerts its cytotoxic and carcinogenic effects ...
Heng Wee Tan +8 more
doaj +1 more source
Molecular mechanisms of follicular lymphoma and its transformation [PDF]
PhDFollicular lymphoma (FL) is the second most common form of non-Hodgkin lymphoma and at least a third of cases undergo aggressive transformation (t-FL), most frequently to diffuse large B-cell lymphoma.
Wrench, David John
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