Results 251 to 260 of about 617,302 (345)

Bioresponsive Hyaluronic Acid‐Based Hydrogel Inhibits Matrix Metalloproteinase‐2 in Glioblastoma Microenvironment

ChemMedChem, EarlyView.
A bioresponsive hydrogel based on hyaluronic acid crosslinked with a MMP inhibitor (HA‐MMPI) is generated to modulate the glioblastoma multiforme (GBM) microenvironment. In preliminary tests with 3D U87 models, HA‐MMPI selectively inhibits MMP‐2, reducing cell migration.
Federica Barbugian, Domenico Salerno, Elisa Ballarini, Luca Crippa, Oscar Francesconi, Francesco Mantegazza, Guido Cavaletti, Stefano Roelens, Gemma Leone, Simone Pepi, Luigi Talarico, Agnese Magnani, Cristina Nativi, Laura Russo   +13 more
wiley   +1 more source

Metastatic choriocarcinoma after a rupture of neoplastic cerebral aneurysm with dural and brain parenchymal lesions: illustrative case. [PDF]

J Neurosurg Case Lessons
Tamai S, Kinoshita M, Iwadare J, Misaki K, Nakada M.   +4 more
europepmc   +1 more source

Targeted Delivery of Lidocaine in Breast Cancer Cells via Zeolitic Imidazolate Framework‐8 Nanoparticles

ChemPhysChem, EarlyView.
Drug repositioning of lidocaine from local anesthetic to theranostic agent for breast cancer cells is enhanced by its encapsulation inside ZIF‐8 metal–organic framework. The aim of this article is to use zeolitic imidazolate framework‐8 (ZIF‐8) metal–organic frameworks (MOFs) as drug delivery system for lidocaine, a local anesthetic with recently ...
Nicola di Nicola, Luca Giacchi, Marco Vandone, Marcello Crucianelli, Leonardo Guidoni, Valentina Colombo, Nadia Rucci, Andrea Lazzarini   +7 more
wiley   +1 more source

Implementing Pre‐Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects

Clinical Pharmacology &Therapeutics, EarlyView.
In pediatric oncology, pharmacogenetic guidelines are underutilized and the potential impact of pre‐emptive pharmacogenetic screening remains largely unexplored despite this field's need for individualized approaches. While comprehensive pharmacogenetic guidelines are not yet available for all anticancer drugs, evidence‐based recommendations exist for ...
Emma C. Bernsen, Eugène T.P. Verwiel, Maaike van der Lee, Jesse J. Swen, Marcel Santoso, Leiah J. Brigitha, Rick Admiraal, Bastiaan B.J. Tops, Alwin D.R. Huitema, Patrick Kemmeren, Jayne Y. Hehir‐Kwa, Lidwien M. Hanff, Meta H.M. Diekstra   +12 more
wiley   +1 more source

Managing IEC-associated enterocolitis following CAR-T therapy in multiple myeloma. [PDF]

Blood Cancer J
Banerjee R, Hosoya H, Mikkilineni L, Hansen DK, Wolf JL, Lin Y.   +5 more
europepmc   +1 more source

Semaglutide impairs bioavailability of alectinib: a note of warning based on a cross‐over pharmacokinetic drug‐drug interaction study

Cancer Communications, EarlyView.
Niels Heersche, Daan A. C. Lanser, Esther Oomen‐de Hoop, Attila Içli, Peter de Bruijn, Marthe S. Paats, Elisabeth F. C. van Rossum, Stijn L. W. Koolen, Ron H. N. van Schaik, Anne‐Marie C. Dingemans, G. D. Marijn Veerman, Ron H. J. Mathijssen   +11 more
wiley   +1 more source

Critical Pitfalls in the Flow Cytometric Analysis of Mast Cells in Patients With Systemic Mastocytosis

Cytometry Part A, EarlyView.
ABSTRACT Systemic mastocytosis (SM) is a neoplastic disease characterized by abnormal mast cell (MC) activation and proliferation. Accurate diagnosis often relies on flow cytometry to detect aberrant CD25, CD2, and CD30 expression on MCs in bone marrow (BM).
Abdulrazzaq Alheraky, Kees Meijer, Marije T. Nijk, Saskia K. Klein, Hanneke N. G. Oude Elberink, Ido P. Kema, André B. Mulder   +6 more
wiley   +1 more source

Lectin-Histochemical Pattern on the Cystic and Neoplastic Ovaries of Bitches. [PDF]

Reprod Domest Anim
Terra JP, Almeida TB, Rezende LPO, Barbeito CG, Acuña F, Blume GR, Eloi RSA, Oliveira LB, Santos ALRM, Sant'Ana FJF.   +9 more
europepmc   +1 more source

Cell‐free DNA blood‐based test compared to fecal immunochemical test for colorectal cancer screening

Cancer Communications, EarlyView.
Teresa Seum, Michael Hoffmeister, Hermann Brenner   +2 more
wiley   +1 more source

Errors in Figure and Supplement 1.

JAMA Netw Open
europepmc   +1 more source