Results 161 to 170 of about 330,598 (225)

Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours

open access: yesAndrology, EarlyView.
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody   +6 more
wiley   +1 more source

Perinatal outcomes and maternal health before and after single motherhood through assisted conception: A multiregistry study in Sweden

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Single mothers through assisted conception in Sweden face higher psychiatric risks before and after childbirth compared to partnered women through autologous IVF. Despite comparable perinatal outcomes, our findings highlight the need for comprehensive preconception medical screening and postpartum psychosocial support for these mothers.
Evangelia Elenis   +5 more
wiley   +1 more source

Parity Influences the Immune Profile of Human Milk via Increased T Lymphocyte Content

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Breast milk contains immune cells, but the factors influencing their composition are not fully understood. The role of maternal reproductive history in shaping this composition has largely been overlooked. The aim of this study was to evaluate the content of leukocytes, stem cells, and lactocytes in the milk of primiparous mothers compared
Agata Tomaszewska   +10 more
wiley   +1 more source

Feline leukaemia virus (FeLV) infection in domestic pet cats in Australia and New Zealand: Guidelines for diagnosis, prevention and management

open access: yesAustralian Veterinary Journal, EarlyView.
Progressive feline leukaemia virus (FeLV) infection dramatically shortens the lives of infected cats, causing acquired immunodeficiency, aplastic anaemia, lymphoma, leukaemia and other myeloproliferative diseases. The potential impact of regressive FeLV infection on the development of disease remains largely unknown, although there is evidence it ...
ME Westman   +6 more
wiley   +1 more source

CD123‐targeting immunotherapeutic approaches in acute myeloid leukaemia

open access: yesBritish Journal of Haematology, EarlyView.
Summary Treatment of relapsed or refractory acute myeloid leukaemia (AML) has remained a significant challenge, with limited available targeted immunotherapies. CD123, or the interleukin‐3 (IL‐3) receptor, has long been known as a potential target expressed on AML blasts, and a range of different approaches to targeting CD123 have been trialled with ...
Alexandra Dreyzin   +2 more
wiley   +1 more source

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