Results 151 to 160 of about 4,884,808 (294)

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Laboratory Identification of Pseudohypercalcemia Induced by Hyperglobulinemia in Multiple Myeloma: A Case Report

Journal of Clinical Laboratory Analysis, EarlyView.
Pseudohypercalcemia induced by calcium‐binding monoclonal immunoglobulin in multiple myeloma is verified via laboratory assays and validated by therapeutic response. ABSTRACT Background Pseudohypercalcemia is easily misdiagnosed in clinical practice, potentially leading to unnecessary interventions.
Anjiang Zhao, Fan Zhong, Yankui Liu, Guixing Li   +3 more
wiley   +1 more source

Measurements of Liver and Bone Marrow Proton Density Fat Fraction in the Setting of Ferumoxytol‐Enhanced MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Proton density fat fraction (PDFF) is typically measured using confounder‐corrected, multi‐echo, gradient‐recalled‐echo chemical‐shift‐encoded (CSE)‐MRI. Ferumoxytol, an iron‐based MRI contrast agent, increases liver and bone marrow (BM) R2*, a major confounder of PDFF.
Lukas Müller, Srijyotsna Volety, Jan‐Peter Grunz, Fatemeh Rashidi, Scott B. Reeder, Diego Hernando, Ali Pirasteh   +6 more
wiley   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Health risk assessment of heavy metal accumulation in fruits exposed to geothermal waters: a case study and global implications

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The present study investigated the potential health risks of heavy metals (HMs) in the fruits and leaves of mulberry and sour cherry trees exposed to water from Sivas geothermal basin (Turkey). RESULTS The target HMs were ranked according to their hazard index as: Cd < Pb < Zn < Cu < Ni < Mn < Cr. The total hazard index for mulberry
E Işıl Arslan Topal, Murat Topal, Erdal Çelik, Erdal Öbek   +3 more
wiley   +1 more source

Extended Versus Non‐Extended Lymphadenectomy in Radical Cystectomy for Bladder Cancer: A Systematic Review and Meta‐Analysis

Journal of Surgical Oncology, EarlyView.
ABSTRACT Pelvic lymph node dissection is an essential component of radical cystectomy (RC) for bladder cancer (BC), but the optimal extent of lymphadenectomy remains uncertain. We conducted a systematic review and meta‐analysis to compare oncologic and perioperative outcomes between extended and non‐extended lymphadenectomy during RC for BC.
Maria Fernanda Dias Azevedo, Pedro Henrique Souza Brito, Lucas Kallas‐Silva, Bruno Liebl, Beatriz Taveira Constantinou, Bianca Caroline Benedicto, Lucas Paschoalino de Oliveira, Mauricio Dener Cordeiro, William Carlos Nahas, Walid Shabana, Walid Shahrour, Leopoldo Alves Ribeiro‐Filho, Caio Vinicius Suartz   +12 more
wiley   +1 more source

LC‐OCT Features in Vitiligo: A Preliminary Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Vitiligo is a chronic depigmenting disorder characterized by the selective loss of melanocytes, leading to the progressive development of hypopigmented macules and patches. Line‐field confocal optical coherence tomography (LC‐OCT) is a novel imaging technique that combines the advantages of optical coherence tomography (OCT) and ...
Gerardo Palmisano, Daniele Omar Traini, Lorenzo Maria Pinto, Alessandra D'Amore, Mariano Suppa, Alessandro Di Stefani, Ketty Peris   +6 more
wiley   +1 more source