Results 161 to 170 of about 4,884,808 (294)

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang, Zhi‐Yan Jin, Min‐Ying Lydia Su   +2 more
wiley   +1 more source

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang, Hong‐Cheng Wei, Lin Jiang, Yi‐Sen Shao   +3 more
wiley   +1 more source

Spheroid‐based matrix‐induced autologous chondrocyte implantation combined with autologous bone grafting restores physiological cartilage and subchondral bone properties in osteochondral knee defects ‐ An MRI‐based analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to evaluate the radiological and patient‐reported outcome measures (PROMs) following spheroid‐based matrix‐induced autologous chondrocyte implantation combined with autologous bone grafting (MABCI) for the treatment of osteochondral defects of the knee.
Stephan Oehme, Benjamin Bartek, Janne Callsen, Jessica Schallock, Tobias Winkler, Thorsten Diekhoff, Tobias Jung, Danko Dan Milinkovic   +7 more
wiley   +1 more source

Beyond the Brain: Circulating Tumor Cells as a Tool for Diagnosis and Monitoring. [PDF]

JCO Precis Oncol
Lessi F, Morelli M, Di Gangi A, Franceschi S, Di Lorenzo F, Sandro C, Aretini P, Pastore A, Ferri G, Menicagli M, Pasqualetti F, Gambacciani C, Villanacci F, Zucchi V, Cupini S, Di Stefano AL, Santonocito OS, Mazzanti CM.   +17 more
europepmc   +1 more source

Contemporary Treatment Patterns in Surgically Treated Temporal Bone Cancer

The Laryngoscope, EarlyView.
In a national cohort of 811 surgically treated temporal bone cancer patients, adjuvant radiation therapy was the most frequently utilized postoperative treatment (20.3%), while chemotherapy and immunotherapy were used far less frequently. Multimodal treatment, particularly combined parotidectomy and neck dissection, was strongly associated with higher ...
Raquel Rowell, Christopher Z. Wen, Vera Bzhilyanskaya, Jane Y. Tong, Adam C. Kaufman   +4 more
wiley   +1 more source

Leukemic presentation of ALK-positive anaplastic large cell lymphoma in an adult patient with hemophagocytic lymphohistiocytosis. [PDF]

J Hematop
Oliver M, Byrd J, Matkovic E.
europepmc   +1 more source

Multiomics Insights Into AL Amyloidosis

Medicine Bulletin, EarlyView.
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang, Ziru Huang, Haoxiang Tang, Xianrun Pan, Rong Wang, Dingding Zhang, Jian Huang   +6 more
wiley   +1 more source

Molecular Mechanisms and Biomarkers Driving the Transition From Chronic Atrophic Gastritis to Gastric Cancer. [PDF]

Clin Med Insights Oncol
Suleimenov Y, Samigatova A, Seksenbayev B, Altaeva N, Zhorayeva A, Bakytzhan A, Bekbayev A.   +6 more
europepmc   +1 more source

Synovial cells express thymidine phosphorylase in inflammatory and neoplastic synovial tissue

Synovial cells (SCs) in pathological conditions of synovial tissue were analyzed by means of paraffin-immunohistochemistry in points of immunological phenotypes，which are usually expressed in monocytes/macrophages and dendritic cells.
Sakae, Kiyohiro, Akiyama, Shin-Ichi, Hayata, Takashi, Murata, Fusayoshi, Hasui, Kazuhisa, Sato, Eiichi, Yonezawa, Suguru, Tsuyama, Shin-Ichiro, Izumo, Shuji   +8 more
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The architecture of neoplastic follicles in follicular lymphoma; analysis of the relationship between the tumor and follicular helper T-cells

, 2019
CD4+ T-follicular helper cells are essential for the survival, proliferation, and differentiation of germinal center B-cells and have been implicated in the pathogenesis of follicular lymphoma.
Elizabeth H Phillips (16276052), Marta Pasikowska (16258118), Stephen Devereux (262370), Jonathan R Sailsbury (16276058), Andrea Pepper (4467784), William Townsend (15023085), Deborah Yallop (14899937), Robert Marcus (15016310), Piers E M Patten (16276055)   +8 more
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