Results 131 to 140 of about 217,168 (254)

CXCL13 as a simple and promising blood biomarker for differentiating Sézary syndrome from mycosis fungoides and other confounding chronic inflammatory skin diseases. [PDF]

Front Immunol
Salvatore G, Minafò YA, Croce N, Passarelli F, Cristofoletti C, Picchio MC, Bonmassar L, Madonna S, Mercurio L, Monopoli A, Russo F, Moretta G, Scala E, D'Atri S, Narducci MG.   +14 more
europepmc   +1 more source

Redox‐responsive dual‐drug nanomedicine integrating cisplatin and trypsin for synergistic reversal of tumor chemoresistance

Smart Molecules, EarlyView.
This study presents a novel glutathione‐activatable prodrug nanomedicine (cRGD‐PEG‐PGlu‐NP (ssTrypsin & CDDP)) that co‐encapsulates cisplatin and a masked protease to combat cisplatin resistance. The dual‐drug system selectively targets resistant tumor cells, enhancing the efficacy of cisplatin while minimizing systemic toxicity.
Xiaolan Yin, Qi Wang, Ming Zhang, Cheng Zhang, Qixian Chen, Haidong Li, Yan Zhao, Yue Wang, Jingyun Wang, Liuwei Zhang, Hongyan Cui   +10 more
wiley   +1 more source

Revisiting the Origins of Cutaneous T-Cell Lymphoma: A Progenitor-Based Model. [PDF]

Cancers (Basel)
Zhang Y, Sokol L.
europepmc   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Clinical Implications of Polyploid Giant Cancer Cells in Solid Tumors: Biology, Diagnosis, and Therapeutic Considerations. [PDF]

Cancers (Basel)
Imaoka H, Ikeda M, Wakabayashi M, Umemoto K, Satake T, Sunakawa Y, Ueno H, Hara K, Nagashima F, Kataoka S, Hisano T, Suzuki Y, Asagi A, Shioji K, Oshima K, Tsuji K, Ohkawa K, Miki I, Kawamoto Y, Yamashita T, Ueno M, Kawakami Y, Nagano H, Okuyama H, Naganuma A, Suzuki R, Furuse J, Japan Oncology Network in Hepatobiliary and Pancreas.   +27 more
europepmc   +1 more source

Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs

Veterinary Record, EarlyView.
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin, Ariadne Rein, Isabella de Almeida Fabris, Beatriz Gasser, Luiz Paulo Nogueira Aires, Bruna Bressianini Lima, Daniele Azevedo Gandra, Daniela Gomes da Silva, Ricardo Andrés Ramirez Uscategui, Gabriela Castro Lopes Evangelista, Marcus Antônio Rossi Feliciano, Paola Castro Moraes   +11 more
wiley   +1 more source

A multimodal single-cell framework for ecosystem-level profiling of circulating tumor and non-tumor cells. [PDF]

Exp Hematol Oncol
Felix G, Aguirre F, Zhou L, Denmark A, Alvarez R, Kim DM, Gong J, Hitchins MP.   +7 more
europepmc   +1 more source

Whole‐transcriptome sequencing analyses identified exosomal circular RNAs in the plasma of pancreatic cancer patients as novel blood‐based biomarkers of disease

VIEW, EarlyView.
Pancreatic cancer (PaCa) has a poor prognosis, with low resection rates and high relapse rates, highlighting the urgent need for novel diagnostic biomarkers. Here, we performed whole‐transcriptome sequencing of plasma‐derived exosomes from PaCa patients and identified several differentially expressed circular RNAs (circRNAs).
Xiaomeng He, Yang Di, Lixiang Sun, Zhirong Wu, Mengting Luo, Xin Zhang, Huaqin Sun, Wanli Xu, Wenchuan Wu, Boheng Zhang, Jin Wang   +10 more
wiley   +1 more source

When Lymph Nodes Don't Lie: Report of Three Unusual Presentations of Thoracic Tumors. [PDF]

Diagnostics (Basel)
Lucà S, Barbato F, Di Maio A, Montella L, Farese S, Di Guida G, Leonardi B, Giannatiempo R, Salvi R, Montella M, Della Corte CM, Fasano M, Orditura M, Fiorelli A, Morgillo F, Franco R.   +15 more
europepmc   +1 more source

Apo10 and TKTL1 as novel liquid biopsy biomarkers for early detection of gastrointestinal malignancies

VIEW, EarlyView.
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao, Qiyu Huang, Juan Xiao, Ziyu Liu, Xinyan Zou, Yuying Liu, Lizhi Liu, Musheng Zeng, Chuanbo Xie   +8 more
wiley   +1 more source