Results 121 to 130 of about 4,884,808 (294)

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Circulating Neoplastic-Immune Hybrid Cells Are Biomarkers of Occult Metastasis and Treatment Response in Pancreatic Cancer

Cancers
Background/Objectives: Pancreatic ductal adenocarcinoma (PDAC) presents significant diagnostic and prognostic challenges, as current biomarkers frequently fail to accurately stage disease, predict rapid metastatic recurrence (rPDAC), or assess response to neoadjuvant therapy (NAT).
Ranish K. Patel, Michael Parappilly, Hannah C. Farley, Emile J. Latour, Lei G. Wang, Ashvin M. Nair, Ethan S. Lu, Zachary Sims, Byung Park, Katherine Nelson, Skye C. Mayo, Gordon B. Mills, Brett C. Sheppard, Young Hwan Chang, Summer L. Gibbs, Adel Kardosh, Charles D. Lopez, Melissa H. Wong   +17 more
openaire   +2 more sources

Fetal cells in maternal circulation : fetal cell separation and FISH analysis [PDF]

, 2005
This work focuses on the isolation of fetal cells from the blood of pregnant women, with the aim of developing safe, efficacious, non-invasive alternatives for prenatal diagnosis.
Babochkina, Tatiana Ivanovna
core   +1 more source

Circulating monocyte partitioning and its alteration in hematological chronic neoplasms

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Circulating monocyte partitioning refers to the relative quantification of the three main monocyte subsets in the peripheral blood, namely classical (cMo), intermediate (iMo), and non‐classical (ncMo) monocytes, as assessed by flow cytometry, a new nomenclature described 15 years ago.
Sihem Tarfi, Dorothée Selimoglu‐Buet, Ivan Sloma, Orianne Wagner‐Ballon, on behalf of the French group CytHem‐LMMC   +4 more
wiley   +1 more source

Research progress of CTC, ctDNA, and EVs in cancer liquid biopsy

Frontiers in Oncology
Circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and extracellular vehicles (EVs) have received significant attention in recent times as emerging biomarkers and subjects of transformational studies.
Xiaoling Wang, Xiaoling Wang, Lijuan Wang, Lijuan Wang, Haihong Lin, Haihong Lin, Yifan Zhu, Yifan Zhu, Defa Huang, Mi Lai, Xuxiang Xi, Junyun Huang, Junyun Huang, Wenjuan Zhang, Wenjuan Zhang, Tianyu Zhong, Tianyu Zhong   +16 more
doaj   +1 more source

Targeting intratumoral B cells with rituximab in addition to CHOP in angioimmunoblastic T-cell lymphoma. A clinicobiological study of the GELA

Haematologica, 2012
Background In angioimmunoblastic T-cell lymphoma, symptoms linked to B-lymphocyte activation are common, and variable numbers of CD20+ large B-blasts, often infected by Epstein-Barr virus, are found in tumor tissues.
Marie-Hélène Delfau-Larue, Laurence de Leval, Bertrand Joly, Anne Plonquet, Dominique Challine, Marie Parrens, Alain Delmer, Gilles Salles, Franck Morschhauser, Richard Delarue, Pauline Brice, Reda Bouabdallah, Olivier Casasnovas, Hervé Tilly, Philippe Gaulard, Corinne Haioun   +15 more
doaj   +1 more source

Extended routine lymphocyte immunophenotyping refines individual immune organization across a heterogeneous patient cohort

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Routine TBNK immunophenotyping detects the major lymphocyte compartments but may underestimate the biologically relevant variation contributed by less frequent but well‐defined minor lymphocyte subsets. This study evaluated whether extending routine TBNK immunophenotyping with minor lymphocyte subsets provides complementary, analytically ...
Carlos Agustin Villegas Valverde, Yendry Ventura Carmenate, Vianed Marsan Suarez, Yandy Marx Castillo Aleman, Imilla Casado Hernandez, Rachely Hernandez Corrales   +5 more
wiley   +1 more source

Development of an in vitro model for investigating the properties of human prostate epithelial cells and prostatic carcinoma cells [PDF]

, 2009
Prostate cell lines were derived from two regions of prostate tissue from the same patient. The objective was to produce cell lines (as a useful in vitro model) from these two different regions which exhibit different properties for carcinoma development.
Weaver, Jennifer
core   +2 more sources

T- and NK-cell populations with regulatory phenotype and markers of apoptosis in circulating lymphocytes of patients with CIN3 or microcarcinoma of the cervix: evidence for potential mechanisms of immune suppression

Infectious Agents and Cancer, 2017
Background Processes and mechanisms responsible for systemic immune suppression in early-stage cervical cancer remain substantially underinvestigated.
Olga V. Kurmyshkina, Pavel I. Kovchur, Ludmila V. Schegoleva, Tatyana O. Volkova   +3 more
doaj   +1 more source