Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms
ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Simo Du +9 more
wiley +1 more source
Estrogen receptor α (<i>Esr1</i>) mediates estrogen's ability to promote papillomavirus-induced cutaneous disease in male and female mice. [PDF]
Umar SA +9 more
europepmc +1 more source
Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel +5 more
wiley +1 more source
Pathological P-Selectin Upregulation Promotes Retinal Ganglion Cell Degeneration Accompanied by T-Cell Recruitment in Glaucoma. [PDF]
Xiu W +9 more
europepmc +1 more source
ABSTRACT Introduction Accurate preoperative physiological assessment is critical for high‐risk patients undergoing lung resection to predict postoperative lung function. This study compared quantitative dual‐energy CT (DECT) perfusion with SPECT/CT for lobar perfusion mapping in an at‐risk oncological cohort.
Jack Edward Liu +6 more
wiley +1 more source
Atomic force microscopy-based nanomechanical signatures as cancer biomarkers in a nutshell. [PDF]
Stylianou A.
europepmc +1 more source
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan +5 more
wiley +1 more source
Inflammatory bowel disease and prostate cancer: from epidemiological controversy to mechanistic hypotheses. [PDF]
Yu T, Zhang L, Li D, Wang Y.
europepmc +1 more source
Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz +22 more
wiley +1 more source
Radiation biomarkers in body fluids: translational perspectives for precision radiotherapy-a narrative review. [PDF]
Monzen S +7 more
europepmc +1 more source

