Results 11 to 20 of about 28,233 (215)

Hereditary colorectal cancer: genetics and screening diagnostics

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of review. To present the data on main forms of hereditary colorectal cancer (CRC) and to discuss issues of its diagnostics, genetic testing and patient management. Summary.
O. I. Kit, D. I. Vodolazhsky, Yu. A. Gevorkyan, N. V. Soldatkina, F. N. Grechkin, M. A. Kozhushko, I. Yu. Yefimova   +6 more
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Familial Pancreatic Cancer and the Future of Directed Screening

Gut and Liver, 2017
Pancreatic cancer (PC) is the third most common cause of cancer-related death in the United States and the 12th most common worldwide. Mortality is high, largely due to late stage of presentation and suboptimal treatment regimens. Approximately 10% of PC
Sara Welinsky, Aimee L. Lucas
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FROM FAMILIES SYNDROMES TO GENES… THE FIRST CLINICAL AND GENETIC CHARACTERIZATIONS OF HEREDITARY SYNDROMES PREDISPOSING TO CANCER: WHAT WAS THE BEGINNING?

Revista Médica Clínica Las Condes, 2017
Assessment for hereditary susceptibility to cancer is considered standard of care, as it impacts not only a clinician's understanding of cancer causation but also options for prevention and treatment.
Charité Ricker, MS, LCGC
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Safety and efficacy of chemoprevention for familial adenomatous polyposis: a systematic review and meta-analysis [PDF]

Annals of Coloproctology
Purpose Familial adenomatous polyposis is a hereditary condition that predisposes individuals to colorectal cancer. This study aimed to evaluate the efficacy and safety of pharmacological therapies for reducing polyp number, burden, and size in ...
Francisco Tustumi, Amanda Park, Eric Toshiyuki Nakamura, Thaís Cabral de Melo Viana, Elis Nogara Lisboa, Rodrigo Moisés de Almeida Leite, Sergio Eduardo Alonso Araujo, Pedro Luiz Serrano Usón Jr, Kaique Flávio Xavier Cardoso Filardi   +8 more
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Increased risk for uterine cancer among first-degree relatives to Swedish gastric cancer patients

Hereditary Cancer in Clinical Practice, 2020
Purpose In order to further understand genetically predisposing factors of gastric cancer, a retrospective study on 107 patients with gastric cancer was conducted.
Johanna Samola Winnberg, Eva Rudd, Anne Keränen, Kristina Lagerstedt-Robinson, Annika Lindblom, Magnus Nilsson, Mats Lindblad, Krister Sjödahl   +7 more
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Reed’s Syndrome: A Rare Systemic Genodermatosis

Gazeta Médica, 2023
Reed’s syndrome is an autosomal dominant rare genodermatosis, characterized by the presence of multiple cutaneous and uterine leiomyomatosis. This syndrome can be associated with renal cell carcinoma and leiomyosarcoma.
Madalena Braga, Leonor Ferreira da Silva, Nuno Mendanha Pereira, Gustavo Fernandes, Miguel Magalhães   +4 more
doaj  

Additional germline findings from a tumor profiling program

BMC Medical Genomics, 2018
Background Matched tumor-normal sequencing, applied in precision cancer medicine, can identify unidentified germline Medically Actionable Variants (gMAVS) in cancer predisposition genes. We report patient preferences for the return of additional germline
Neda Stjepanovic, Tracy L. Stockley, Philippe L. Bedard, Jeanna M. McCuaig, Melyssa Aronson, Spring Holter, Kara Semotiuk, Natasha B. Leighl, Raymond Jang, Monika K. Krzyzanowska, Amit M. Oza, Abha Gupta, Christine Elser, Lailah Ahmed, Lisa Wang, Suzanne Kamel-Reid, Lillian L. Siu, Raymond H. Kim   +17 more
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Urological cancer related to familial syndromes

International Brazilian Journal of Urology
Cancer related to hereditary syndromes corresponds to approximately 5-10% of all tumors. Among those from the genitourinary system, many tumors had been identified to be related to genetic syndromes in the last years with the advent of new molecular ...
Walter Henriques da Costa, George Jabboure Netto, Isabela Werneck da Cunha   +2 more
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Metastatic follicular thyroid cancer in a patient with Birt‐Hogg‐Dubé syndrome

Clinical Case Reports, 2021
Birt‐Hogg‐Dubé syndrome (BHDS) is an extremely rare genetic condition that predisposes to renal cell carcinoma. This case describes a novel case of a patient with BHDS who also develops follicular thyroid cancer.
Elisa K. Bongetti, Rajesh Raj, Duncan R. Cooke, Mathew C. Mathew   +3 more
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Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal

HemaSphere, 2021
Mastocytosis is a hematologic neoplasm characterized by expansion and focal accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone marrow (BM), spleen, liver, and gastrointestinal tract.
Peter Valent, Cem Akin, Karin Hartmann, Ivan Alvarez-Twose, Knut Brockow, Olivier Hermine, Marek Niedoszytko, Juliana Schwaab, Jonathan J. Lyons, Melody C. Carter, Hanneke Oude Elberink, Joseph H. Butterfield, Tracy I. George, Georg Greiner, Celalettin Ustun, Patrizia Bonadonna, Karl Sotlar, Gunnar Nilsson, Mohamad Jawhar, Frank Siebenhaar, Sigurd Broesby-Olsen, Selim Yavuz, Roberta Zanotti, Magdalena Lange, Boguslaw Nedoszytko, Gregor Hoermann, Mariana Castells, Deepti H. Radia, Javier I. Muñoz-Gonzalez, Wolfgang R. Sperr, Massimo Triggiani, Hanneke C. Kluin-Nelemans, Stephen J. Galli, Lawrence B. Schwartz, Andreas Reiter, Alberto Orfao, Jason Gotlib, Michel Arock, Hans-Peter Horny, Dean D. Metcalfe   +39 more
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