Results 11 to 20 of about 12,655 (161)

Efficacy and Safety of Neostigmine Adjunctive Therapy in Patients With Sepsis or Septic Shock: A Randomized Controlled Trial

Frontiers in Pharmacology, 2022
Background: Neostigmine has been found to improve survival in animal models of sepsis. However, its feasibility, efficacy, and safety in patients with sepsis or septic shock have not been investigated.Aim: This parallel randomized controlled double ...
Mona M. El-Tamalawy, Moetaza M. Soliman, Amany F. Omara, Amal Rashad, Osama M. Ibrahim, Mamdouh M. El-Shishtawy   +5 more
doaj   +1 more source

Sugammadex reversal of muscle relaxant blockade provided less Post-Anesthesia Care Unit adverse effects than neostigmine/glycopyrrolate

Journal of the Formosan Medical Association, 2022
Sugammadex is a direct reversal agent of aminosteroid muscle relaxants, particularly rocuronium, with promptly and completely reverse of deep neuromuscular block (NMB), which allows better surgical conditions. Sugammadex exhibits advantages over indirect
Hsiao-Cheng Chang, Shih-Yuan Liu, Min-Jia Lee, Sing-Ong Lee, Chih-Shung Wong   +4 more
doaj   +1 more source

New advances in clinical application of neostigmine: no longer focusing solely on increasing skeletal muscle strength

Frontiers in Pharmacology, 2023
Neostigmine is a clinical cholinesterase inhibitor, that is, commonly used to enhance the function of the cholinergic neuromuscular junction. Recent studies have shown that neostigmine regulates the immune-inflammatory response through the cholinergic ...
Shangkun Si, Xiaohu Zhao, Fan Su, Hongxiu Lu, Dongbin Zhang, Li Sun, Fulei Wang, Li Xu   +7 more
doaj   +1 more source

Epidural co-administration of neostigmine and lidocaine or xylazine enhances systemic sedation but not perineal analgesia in adult dairy cows

Veterinární Medicína, 2018
The aim of this study was to evaluate the behavioural, clinical and analgesic effects of epidural neostigmine in adult dairy cattle. Five healthy, adult Holstein-Friesian dairy cows received five different treatments in a cross-over design with one-week ...
Z.B. Ismail, E. Abu-Basha, A. Alzghoul, A. Salah, I. Al-Zoubi   +4 more
doaj   +1 more source

Randomized controlled trial: neostigmine for intra-abdominal hypertension in acute pancreatitis

Critical Care, 2022
Background Intra-abdominal hypertension (IAH) in acute pancreatitis (AP) is associated with deterioration in organ function. This trial aimed to assess the efficacy of neostigmine for IAH in patients with AP.
Wenhua He, Peng Chen, Yupeng Lei, Liang Xia, Pi Liu, Yong Zhu, Hao Zeng, Yao Wu, Huajing Ke, Xin Huang, Wenhao Cai, Xin Sun, Wei Huang, Robert Sutton, Yin Zhu, Nonghua Lu   +15 more
doaj   +1 more source

Routine administration of neostigmine after recovery of spontaneous breathing versus neuromuscular monitor-guided administration of neostigmine in pediatric patients: a parallel, randomized, controlled study

Trials, 2023
Background Neostigmine used to reverse the muscle relaxants should be guided by neuromuscular monitoring, as the degree of spontaneous pre-reversal recovery is the key to success to reverse the neuromuscular block.
Lei Yang, Na Hu, Hong Chang, Di Yang, Yunxia Zuo   +4 more
doaj   +1 more source

The interaction of intrathecal neostigmine and N-cyclohexyladenosine on anti-allodynic effects in rats with a nerve ligation injury [PDF]

Korean Journal of Anesthesiology, 2010
BackgroundNerve ligation injury in rats produces a pain syndrome that includes mechanical allodynia. Intrathecal administration of cholinesterase inhibitors or adenosine receptor agonists have anti-allodynic effects in this model.
Dae Kee Choi, Seong Soo Choi, Jai Hyun Hwang   +2 more
doaj   +1 more source

Dose-reversal effect relationship of three different doses of neostigmine in obese patients: A randomised clinical trial

Indian Journal of Anaesthesia, 2017
Background and Aims: Previous studies suggest that administration of vecuronium based on total body weight rather than ideal body weight (IBW) in obesity results in overdosing with prolonged recovery times.
Satyen Parida, Venkatesan Kausalya, Sandeep Kumar Mishra, Sethuramachandran Adinarayanan   +3 more
doaj   +1 more source

Effective and Safe Use of Neostigmine in Treatment of Acute Kidney Injury Associated with Colonic Pseudo-obstruction after Cardiac Surgery

The Korean Journal of Gastroenterology, 2016
Neostigmine can successfully decompress patients with acute colonic pseudo-obstruction (ACPO) who are unresponsive to conservative therapy. However, neostigmine is contraindicated in renal failure, so it is underused in ACPO patients with renal failure ...
Jeung Hui Pyo, Yang Won Min, Poong-Lyul Rhee   +2 more
doaj   +1 more source

Addition of Neostigmine and Tramadol to 1.5 % Lidocaine for paracervical block to reduce post-operative pain in colporrhaphy

European Journal of Translational Myology, 2018
Pain is a complex and multi-faceted human perception and several factors could dampen the pain. Therefore, we aimed to comparison of addition of neostigmine and tramadol to 1.5 % lidocaine with paracervical block in reduce of post-operative pain in ...
Alireza Kamali, Maryam Shokrpour, Bijan Yazdi, Atefeh Khalilpour   +3 more
doaj   +1 more source