Results 11 to 20 of about 17,045 (186)

Alternative Pathways of Acetylcholine Release in the Colon: Role of High-Affinity Choline Transporters. [PDF]

Neurogastroenterol Motil
Mechanisms of Acetylcholine release, including typical and atypical release under neuronal blockade. Left panel illustrates the classical (quantal) cholinergic transmission and the right panel the mechanism described in the present study. High‐Affinity Choline Transporter (HCT), Acetylcholine (ACh), Acetylcholinesterase (ACE), and Tetrodotoxin (TTX ...
Martinez-Daunis A, Yordanova B, Traserra S, Vergara P, Jimenez M.   +4 more
europepmc   +2 more sources

When manual disimpaction isn't enough: Case report and review of neostigmine's role in refractory constipation management. [PDF]

JPGN Rep
ABSTRACT Severe refractory constipation can lead to fecal retention requiring hospitalization, nasogastric cleanout, or manual disimpaction, and in some cases, surgery. Neostigmine, a reversible acetylcholinesterase inhibitor, is commonly used for pseudo‐obstruction but rarely for refractory constipation. Here, we report a 21‐year‐old male with chronic
Mostafavi M, Lee S, Martin V.
europepmc   +2 more sources

Efficacy and Safety of Neostigmine Adjunctive Therapy in Patients With Sepsis or Septic Shock: A Randomized Controlled Trial

Frontiers in Pharmacology, 2022
Background: Neostigmine has been found to improve survival in animal models of sepsis. However, its feasibility, efficacy, and safety in patients with sepsis or septic shock have not been investigated.Aim: This parallel randomized controlled double ...
Mona M. El-Tamalawy, Moetaza M. Soliman, Amany F. Omara, Amal Rashad, Osama M. Ibrahim, Mamdouh M. El-Shishtawy   +5 more
doaj   +1 more source

Epidural co-administration of neostigmine and lidocaine or xylazine enhances systemic sedation but not perineal analgesia in adult dairy cows

Veterinární Medicína, 2018
The aim of this study was to evaluate the behavioural, clinical and analgesic effects of epidural neostigmine in adult dairy cattle. Five healthy, adult Holstein-Friesian dairy cows received five different treatments in a cross-over design with one-week ...
Z.B. Ismail, E. Abu-Basha, A. Alzghoul, A. Salah, I. Al-Zoubi   +4 more
doaj   +1 more source

Randomized controlled trial: neostigmine for intra-abdominal hypertension in acute pancreatitis

Critical Care, 2022
Background Intra-abdominal hypertension (IAH) in acute pancreatitis (AP) is associated with deterioration in organ function. This trial aimed to assess the efficacy of neostigmine for IAH in patients with AP.
Wenhua He, Peng Chen, Yupeng Lei, Liang Xia, Pi Liu, Yong Zhu, Hao Zeng, Yao Wu, Huajing Ke, Xin Huang, Wenhao Cai, Xin Sun, Wei Huang, Robert Sutton, Yin Zhu, Nonghua Lu   +15 more
doaj   +1 more source

Routine administration of neostigmine after recovery of spontaneous breathing versus neuromuscular monitor-guided administration of neostigmine in pediatric patients: a parallel, randomized, controlled study

Trials, 2023
Background Neostigmine used to reverse the muscle relaxants should be guided by neuromuscular monitoring, as the degree of spontaneous pre-reversal recovery is the key to success to reverse the neuromuscular block.
Lei Yang, Na Hu, Hong Chang, Di Yang, Yunxia Zuo   +4 more
doaj   +1 more source

Pyridostigmine in pediatric Intestinal pseudo-obstruction. case report of a 2-year old girl and literature review [PDF]

, 2019
Pediatric chronic intestinal pseudo-obstruction is a rare disorder characterized by a severe impairment of gastrointestinal motility leading to intestinal obstruction symptoms in the absence of mechanical causes.
Caló, Girolamo, De Giorgio, Roberto, Di Nardo, Giovanni, Esposito, Francesco, Morlando, Alessia, Parisi, Pasquale, Stanghellini, Vincenzo, Villa, Maria Pia, Viscogliosi, Federica   +8 more
core   +2 more sources

Profile of sugammadex for reversal of neuromuscular blockade in the elderly: Current perspectives [PDF]

, 2017
The number of elderly patients is increasing worldwide. This will have a significant impact on the practice of anesthesia in future decades. Anesthesiologists must provide care for an increasing number of elderly patients, who have an elevated risk of ...
Bertoncello, Francesco, Carron, Michele, Ieppariello, Giovanna   +2 more
core   +1 more source

Dose-reversal effect relationship of three different doses of neostigmine in obese patients: A randomised clinical trial

Indian Journal of Anaesthesia, 2017
Background and Aims: Previous studies suggest that administration of vecuronium based on total body weight rather than ideal body weight (IBW) in obesity results in overdosing with prolonged recovery times.
Satyen Parida, Venkatesan Kausalya, Sandeep Kumar Mishra, Sethuramachandran Adinarayanan   +3 more
doaj   +1 more source

The interaction of intrathecal neostigmine and N-cyclohexyladenosine on anti-allodynic effects in rats with a nerve ligation injury [PDF]

Korean Journal of Anesthesiology, 2010
BackgroundNerve ligation injury in rats produces a pain syndrome that includes mechanical allodynia. Intrathecal administration of cholinesterase inhibitors or adenosine receptor agonists have anti-allodynic effects in this model.
Dae Kee Choi, Seong Soo Choi, Jai Hyun Hwang   +2 more
doaj   +1 more source