Results 21 to 30 of about 19,003 (253)

Antinociceptive Effects and Interaction Mechanisms of Intrathecal Pentazocine and Neostigmine in Two Different Pain Models in Rats

open access: yesPain Research and Management, 2022
Background. Pentazocine produces a wide variety of actions in the treatment of perioperative analgesia. Neostigmine is a cholinesterase inhibitor used to antagonize the residual effects of muscle relaxants and also produces an analgesic effect ...
Huiying Huang   +5 more
doaj   +1 more source

Quality of Recovery after Laparoscopic Cholecystectomy Following Neuromuscular Blockade Reversal with Neostigmine or Sugammadex: A Prospective, Randomized, Controlled Trial

open access: yesJournal of Clinical Medicine, 2021
The risk of neuromuscular blockade is certainly minimized by sugammadex in combination with monitoring. However, the effect of sugammadex-aided recovery on patients’ satisfaction is unclear.
Jiwon Han   +6 more
semanticscholar   +1 more source

Efficacy and Safety of Neostigmine Adjunctive Therapy in Patients With Sepsis or Septic Shock: A Randomized Controlled Trial

open access: yesFrontiers in Pharmacology, 2022
Background: Neostigmine has been found to improve survival in animal models of sepsis. However, its feasibility, efficacy, and safety in patients with sepsis or septic shock have not been investigated.Aim: This parallel randomized controlled double ...
Mona M. El-Tamalawy   +5 more
doaj   +1 more source

Sugammadex versus Neostigmine for Reversal of Neuromuscular Blockade and Postoperative Pulmonary Complications (STRONGER)

open access: yesAnesthesiology, 2020
Background: Five percent of adult patients undergoing noncardiac inpatient surgery experience a major pulmonary complication. The authors hypothesized that the choice of neuromuscular blockade reversal (neostigmine vs.
S. Kheterpal   +13 more
semanticscholar   +1 more source

Influence of sugammadex versus neostigmine for neuromuscular block reversal on the incidence of postoperative pulmonary complications: a meta-analysis of randomized controlled trials

open access: yesPerioperative Medicine, 2021
Background The influence of sugammadex for reversal of neuromuscular block (NMB) on postoperative pulmonary complications (PPCs), compared with neostigmine, remains to be determined.
Jia-feng Wang   +4 more
semanticscholar   +1 more source

Efficacy and Safety of Sugammadex versus Neostigmine in Reversing Neuromuscular Blockade in Morbidly Obese Adult Patients: A Systematic Review and Meta-Analysis

open access: yesAnesthesia Essays and Researches, 2021
Context: Sugammadex is known to reverse neuromuscular blockade (NMB) more rapidly and reliably than neostigmine. However, data remain limited in bariatric patients.
Y. Subramani   +5 more
semanticscholar   +1 more source

New advances in clinical application of neostigmine: no longer focusing solely on increasing skeletal muscle strength

open access: yesFrontiers in Pharmacology, 2023
Neostigmine is a clinical cholinesterase inhibitor, that is, commonly used to enhance the function of the cholinergic neuromuscular junction. Recent studies have shown that neostigmine regulates the immune-inflammatory response through the cholinergic ...
Shangkun Si   +7 more
doaj   +1 more source

Efficacy and safety of neostigmine for neuromuscular blockade reversal in patients under general anesthesia: a systematic review and meta-analysis

open access: yesAnnals of Translational Medicine, 2021
Background Since the antagonistic effect of neostigmine on muscle relaxation is still controversial, this study aimed to evaluate the efficacy and safety of neostigmine for the reversal of neuromuscular blockade in patients recovering from general ...
Wentao Ji   +6 more
semanticscholar   +1 more source

Comparison of Sugammadex versus Neostigmine Costs and Respiratory Complications in Patients with Obstructive Sleep Apnoea.

open access: yesTurkish Journal of Anaesthesiology and Reanimation, 2020
OBJECTIVE To compare sugammadex and neostigmine regarding the efficacy in reversing rocuronium-induced neuromuscular block, the incidence of post-operative respiratory complications and costs in patients undergoing surgery for the treatment of ...
Dilek Ünal   +5 more
semanticscholar   +1 more source

Neostigmine and pulmonary oedema [PDF]

open access: yesBMJ Case Reports, 2014
A 1-year-old child with no pre-existing cardiac or respiratory disease developed frank pulmonary oedema after administration of a neostigmine–glycopyrrolate mixture to reverse neuromuscular blockade during general anaesthesia. Possible cardiac and extra-cardiac factors that could cause pulmonary oedema in this child were ruled out by appropriate ...
Amrutha Bindu Nagella   +3 more
openaire   +3 more sources

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