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Management of neovascular age-related macular degeneration
Progress in Retinal and Eye Research, 2007Neovascular age-related macular degeneration (AMD) is becoming an increasing socio-medical problem as the proportion of the aged population is continuously increasing. However, new insights in the pathogenesis of the disease offer the opportunity to develop targeted therapies that attack the disease process more successfully than ever.
Christian Pruente +1 more
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Hyperopia and Neovascularization in Age-related Macular Degeneration
Ophthalmology, 1993Refractive errors for phakic eyes of patients referred with age-related macular degeneration were reviewed to determine whether some range of refractive error might be a risk factor for the neovascular form.The authors compared refractive errors of 198 patients with unilateral neovascular disease with refractive errors of 129 patients with bilateral ...
Michael J. Tolentino +4 more
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Neovascular Age-Related Macular Degeneration [PDF]
Drugs, 2008 Age-related macular degeneration (AMD) affects an estimated 14 million people worldwide, and is the leading cause of severe, irreversible vision loss in individuals over the age of 50 years in Western societies. Choroidal neovascularization (CNV), the hallmark of 'wet', 'exudative' or 'neovascular' AMD, is responsible for approximately 90% of cases of ...
Peter K. Kaiser, Aimee V. Chappelow
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Ranibizumab for neovascular age-related macular degeneration
American Journal of Health-System Pharmacy, 2008The pharmacology, pharmacokinetics, clinical efficacy, safety, pharmacoeconomics, and place in therapy of ranibizumab are reviewed.Ranibizumab is the humanized fragment of the murine monoclonal antibody that binds all the active forms of the vascular endothelial growth factor, leading to the inhibition of the neovascular process underlying age-related ...
Ana Ortega +3 more
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Neovascular Age-Related Macular Degeneration
2013Age-related macular degeneration (AMD) progresses through early and intermediate to advanced stages, one of which is neovascular AMD (nAMD). A correct diagnosis of nAMD at an early stage is critical because unlike geographic atrophy, it can be treated with therapeutic agents.
Bianca S. Gerendas +3 more
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Laser photocoagulation for neovascular age-related macular degeneration
Cochrane Database of Systematic Reviews, 2004Laser photocoagulation was the first treatment introduced to try to halt the progression of neovascular age-related macular degeneration (AMD), in which newly formed vessels or choroidal neovascularisation (CNV) grow under the macula leading to the occurrence of a scotoma or blind spot in the central visual field.The aim of this review was to examine ...
VIRGILI, GIANNI, A. Bini
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Exudative non-neovascular age-related macular degeneration
Graefe's Archive for Clinical and Experimental Ophthalmology, 2020To describe the clinical and multimodal imaging (MMI) features of age-related macular degeneration (AMD) eyes presenting with intraretinal exudation and no evidence of neovascularization or structural alterations of native retinal vessels.This was a retrospective review of the MMI and electronic health records for 3 consecutive patients presenting with
Juliet Essilfie +5 more
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The Nature and Frequency of Neovascular Age-Related Macular Degeneration
European Journal of Ophthalmology, 2007Purpose This study was designed to evaluate the frequency and nature of neovascularization in age-related macular degeneration (ARMD) utilizing the combination of digital imaging techniques, fluorescein angiography (FA), indocyanine green (ICG) angiography, and optical coherence tomography (OCT). Methods A complete clinical examination was performed on
R. Iranmanesh +7 more
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Preferred therapies for neovascular age-related macular degeneration
Current Opinion in Ophthalmology, 2011This report reviews the current treatment strategies and the most recent clinical trials in the treatment of neovascular age-related macular degeneration.The functional and anatomic outcomes achieved in the pivotal ranibizumab trials with monthly injections set the standard for comparison.
Carl D. Regillo +2 more
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Vitreomacular Adhesion and Neovascular Age-Related Macular Degeneration
Survey of Ophthalmology, 2012We explore the hypothesis that vitreomacular adhesion (VMA) and vitreomacular traction (VMT) play a role in the pathogenesis and clinical course of neovascular ("wet") age-related macular degeneration (AMD). Several biological theories are offered to explain this possible association, including direct tractional force, altered vitreous oxygenation ...
Simpson, Andrew R H +2 more
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