Results 51 to 60 of about 17,313 (143)
Advanced Science, Volume 13, Issue 1, 5 January 2026.Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen +12 more
wiley +1 more source
Hypertensive phase and early complications after Ahmed glaucoma valve implantation with intraoperative subtenon triamcinolone acetonide [PDF]
, 2014 Objective: To evaluate intraoperative subtenon triamcinolone acetonide (TA) as an adjunct to Ahmed glaucoma valve (AGV) implantation. Design: Retrospective comparative case series.
Pasquale, Louis R, Turalba, Angela V
core +1 more source
Mass spectrometry in ocular drug research
Mass Spectrometry Reviews, Volume 45, Issue 1, Page 37-68, January/February 2026.Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source
Safety and effectiveness of primary transscleral diode laser cyclophotoablation for glaucoma in Nigeria. [PDF]
, 2018 IMPORTANCE: To investigate the safety, effectiveness and follow-up rates after transscleral diode laser cyclophotocoagulation as primary treatment for seeing eyes with primary open angle glaucoma in Bauchi, Nigeria. BACKGROUND: There is a high prevalence
Balo PK +6 more
core +1 more source
Advances in Deep Learning Applications for Choroidal Images Analysis: A Narrative Review
IET Image Processing, Volume 20, Issue 1, January/December 2026.Clinical detection and evaluation of the choroid primarily rely on imaging and subsequent image analysis. The application of artificial intelligence (AI), particularly deep learning (DL), in the analysis of choroidal images shows significant potential for improving accuracy and efficiency.
Yiwen Shi +5 more
wiley +1 more source
Atypical p38 Kinase Signaling in Retinal Vascular Damage and Recovery
The FASEB Journal, Volume 39, Issue 24, 31 December 2025.Using an oxygen‐induced retinopathy model, we demonstrate that Tab1‐dependent atypical p38 activation contributes to retinal vascular injury. Genetic blockade of this pathway protects against pathological neovascularization by modulating transcriptional programs.
Lillian Schulz +8 more
wiley +1 more source
Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy [PDF]
, 2016 Diabetic retinopathy (DR) affects approximately one-third of diabetic patients and, if left untreated, progresses to proliferative DR (PDR) with associated vitreous hemorrhage, retinal detachment, iris neovascularization, glaucoma and irreversible ...
Bassuk, Alexander G. +12 more
core +2 more sources
Eye &ENT Research, Volume 2, Issue 4, Page 264-274, December 2025.Abstract Background Age‐related macular degeneration (AMD) and diabetic retinopathy (DR) are two prevalent retinal neovascular diseases globally. Although observational studies have suggested a link between micronutrients and both AMD and DR, the causal relationship remains unconfirmed.
Chengzhi Liu +4 more
wiley +1 more source
Anti-vascular endothelial growth factor for proliferative diabetic retinopathy. [PDF]
, 2014 BACKGROUND: Proliferative diabetic retinopathy (PDR) is a complication of diabetic retinopathy that can cause blindness. Although panretinal photocoagulation (PRP) is the treatment of choice for PDR, it has secondary effects that can affect vision.
Buil-Calvo, José A +6 more
core +2 more sources
Acta Ophthalmologica, Volume 103, Issue 8, Page 1049-1057, December 2025.Abstract Purpose To evaluate the clinical features and treatment outcomes of bilateral myopic macular neovascularization (mMNV). Methods This single‐centre retrospective study included patients with bilateral high myopia who were newly diagnosed with unilateral mMNV (first eye) between January 2008 and July 2020.
Soo Hyun Lim +5 more
wiley +1 more source