Results 71 to 80 of about 150,746 (305)

Inhibition of retinopathy of prematurity in rat by intravitreal injection of sorafenib [PDF]

International Journal of Ophthalmology, 2014
AIM:To investigate the effect of intravitreal injection administered sorafenib, a multikinase inhibitor, in a rat model of oxygen-induced retinopathy (OIR).METHODS:Seven-day-old Sprague-Dawley rats (n=144) were randomly assigned to six groups.
Li-Li Tian, Bing Ren, Xiao-Wei Gao, Ying Luo, Yan Cai, Kun Zhou, An-Jie Du, Yong Zhao   +7 more
doaj   +1 more source

Update on therapeutic neovascularization [PDF]

Cardiovascular Research, 2005
Therapeutic neovascularization for cardiovascular ischemia is a promising avenue in spite of disappointing early clinical trial results. The concept of three different mechanisms of neovascularization has served to define potential therapeutic targets such as vascular remodeling and stem cell recruitment, but it is anticipated that this will lose ...
Yihai, Cao, An, Hong, Henny, Schulten, Mark J, Post   +3 more
openaire   +2 more sources

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

Encephaloduroarteriosynangiosis for Symptomatic Intracranial Atherosclerotic Arterial Steno‐Occlusive Disease: Clinical and Radiological Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background This study investigated the long‐term clinical and angiographic outcomes of encephaloduroarteriosynangiosis treatment for symptomatic intracranial atherosclerotic arterial steno‐occlusive disease to further evaluate the potential therapeutic ...
Xiao‐Peng Wang, Bin Ren, Qian‐Nan Wang, Jing‐Jie Li, Jia‐Qi Liu, Dan Yu, Qian Zhang, Xiang‐Yang Bao, Jian‐Ning Zhang, Lian Duan   +9 more
doaj   +1 more source

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source

Pathophysiology of tumor neovascularization

, 2005
Mitsuko Furuya1, Mariko Nishiyama2, Yoshitoshi Kasuya2, Sadao Kimura2, Hiroshi Ishikura11Departments of Molecular Pathology, and 2Biochemistry and Molecular Pharmacology, Chiba University Graduate School of Medicine, Chiba, JapanAbstract ...
Mitsuko Furuya, Yoshitoshi Kasuya, Mariko Nishiyama, Hiroshi Ishikura, Sadao Kimura   +4 more
core  

Modern Approach to Diabetic Retinopathy Diagnostics

Diagnostics
This article reviews innovative diagnostic approaches for diabetic retinopathy as the prevalence of diabetes mellitus and its complications continue to escalate. Novel techniques focus on early disease detection.
Maria Kąpa, Iga Koryciarz, Natalia Kustosik, Piotr Jurowski, Zofia Pniakowska   +4 more
doaj   +1 more source

Comparison of neovascularization detection methods.

, 2013
Comparison of neovascularization detection methods.
Benny Chung Ying Zee (497798), Jack Lee (497797), Qing Li (84975)   +2 more
core   +1 more source

Synergistic Mechano‐Fluidic Self‐Fusion of Poly(Vinyl Alcohol)‐Modified Liquid‐Metal Particles for Post‐Treatment‐Free Soft Electronics

Advanced Science, EarlyView.
Poly(vinyl alcohol)‐modified liquid‐metal particles form conductive networks through spray‐induced self‐fusion without additional post‐treatment. Spray impact initiates oxide‐shell rupture and electrical contact, while subsequent Marangoni flow and capillary forces promote particle redistribution, neck growth, and network consolidation. This sequential
Keun‐Young Yook, Sangwon Kim, Chansoo Kim, Minkyong Kang, Yurim Lee, Mido Kim, Kijun Park, Seung Yeop Han, Seung‐Woo Cho, Gun‐Hee Lee, Kayoung Son, Hanbit Jang, Tae Young Kim, Jungmok Seo   +13 more
wiley   +1 more source

Platelet Factor 4: A Novel Therapeutic Inhibitor for Experimental Neovascular Age-Related Macular Degeneration

Frontiers in Bioscience-Landmark
Background: Platelet factor 4 (PF4/CXCL4) is a chemokine with reported anti-angiogenic and immunomodulatory properties; however, the role of PF4 in neovascular age-related macular degeneration (nAMD) remains unclear.
Xiubin Ke, Shuqi Liang, Tianhao Qu, Shenyu Li, Ji Lei, Han Han, Yingying Guo, Man Xing, Xiaohong Wang, Shikun He, Mengyu Liao, Dongming Zhou, Hua Yan   +12 more
doaj   +1 more source