Results 51 to 60 of about 227,991 (357)

Fenofibrate suppresses corneal neovascularization by regulating lipid metabolism through PPARα signaling pathway

Frontiers in Pharmacology, 2022
Purpose: The purpose of this study was to explore the potential underlying mechanism of anti-vascular effects of peroxisome proliferator–activated receptor α (PPARα) agonist fenofibrate against corneal neovascularization (CNV) through the changes of ...
Tong Zhou, Tong Zhou, Tong Zhou, Ke Yan, Yuhan Zhang, Yuhan Zhang, Linfangzi Zhu, Linfangzi Zhu, Yi Liao, Yi Liao, Xiaoxiang Zheng, Xiaoxiang Zheng, Yongxiong Chen, Yongxiong Chen, Xiaoxin Li, Xiaoxin Li, Xiaoxin Li, Zuguo Liu, Zuguo Liu, Zuguo Liu, Zhaoqiang Zhang, Zhaoqiang Zhang   +21 more
doaj   +1 more source

Reduced Retinal Microvascular Density, Improved Forepaw Reach, Comparative Microarray and Gene Set Enrichment Analysis with c-jun Targeting DNA Enzyme [PDF]

, 2015
Retinal neovascularization is a critical component in the pathogenesis of common ocular disorders that cause blindness, and treatment options are limited.
Chan, Cecilia W. S, Kaplan, Warren, Khachigian, Levon M, Parish, Christopher   +3 more
core   +1 more source

Tumor Neovascularization and Developments in Therapeutics

Cancers, 2019
Tumors undergo fast neovascularization to support the rapid proliferation of cancer cells. Vasculature in tumors, unlike that in wound healing, is immature and affects the tumor microenvironment, resulting in hypoxia, acidosis, glucose starvation, immune
Yuki Katayama, J. Uchino, Y. Chihara, N. Tamiya, Y. Kaneko, Tadaaki Yamada, K. Takayama   +6 more
semanticscholar   +1 more source

A Complete Review of Automatic Detection, Segmentation, and Quantification of Neovascularization in Optical Coherence Tomography Angiography Images

Diagnostics, 2023
Optical coherence tomography (OCT) is revolutionizing the way we assess eye complications such as diabetic retinopathy (DR) and age-related macular degeneration (AMD).
Yar Zar Tun, Pakinee Aimmanee
doaj   +1 more source

Investigation of the marine compound spongistatin 1 links the inhibition of PKCα translocation to nonmitotic effects of tubulin antagonism in angiogenesis [PDF]

, 2009
The aims of the study were to meet the demand of new tubulin antagonists with fewer side effects by characterizing the antiangiogenic properties of the experimental compound spongistatin 1, and to elucidate nonmitotic mechanisms by which tubulin ...
Bruns, Christiane J., Fürst, Robert, Garczarczyk, Dorota, Ischenko, Ivan, Joore, Jos, Rothmeier, Andrea S., Vollmar, Angelika M., Zahler, Stefan   +7 more
core   +1 more source

Chorioallantoic membrane assay as model for angiogenesis in tissue engineering : focus on stem cells [PDF]

, 2020
Tissue engineering aims to structurally and functionally regenerate damaged tissues, which requires the formation of new blood vessels that supply oxygen and nutrients by the process of angiogenesis.
Bronckaers, Annelies, De Spiegelaere, Ward, Lambrichts, Ivo, Lo Monaco, Melissa, Merckx, Greet, Tay, Hanna, van Zandvoort, Marc   +6 more
core   +3 more sources

Neovascular growth factors [PDF]

Eye, 1991
Neovascularisation is the biological process of forming new blood vessels. Many conditions can initiate neovascularisation including trauma or chronic ischaemia produced by diseases such as diabetes. Neovascularisation proceeds through a series of steps beginning with destruction of the basement membrane surrounding the microvascular endothelial cells,
G S, Schultz, M B, Grant
openaire   +2 more sources

Effects of BMPER, CXCL10, and HOXA9 on Neovascularization During Early-Growth Stage of Primary High-Grade Glioma and Their Corresponding MRI Biomarkers

Frontiers in Oncology, 2020
Neovascularization is required in high-grade glioma (HGG). The objective of this study was to explore neovascularization-related genes and their corresponding MRI biomarkers during the early-growth stage of HGG.
Wei Xue, Junfeng Zhang, Haipeng Tong, Tian Xie, Xiao Chen, Bo Zhou, Pengfei Wu, Peng Zhong, Xuesong Du, Yu Guo, Youyuan Yang, Heng Liu, Heng Liu, Jingqin Fang, Shunan Wang, Hao Wu, Kai Xu, Weiguo Zhang, Weiguo Zhang   +18 more
doaj   +1 more source

The proangiogenic capacity of polymorphonuclear neutrophils delineated by microarray technique and by measurement of neovascularization in wounded skin of CD18-deficient mice [PDF]

, 2006
Growing evidence supports the concept that polymorphonuclear neutrophils (PMN) are critically involved in inflammation-mediated angiogenesis which is important for wound healing and repair.
Addison CL, Armstrong DA, Baggiolini M, Barbara Walzog, Bazzoni F, Benelli R, Bernardini G, Bohnsack JF, Brandes ME, Cacalano G, Choudhuri R, Devalaraja RM, Dewald B, Dubravec DB, Gasperini S, Gaudry M, Grant DS, Grenier A, Grotendorst GR, Harada H, Heiple JM, Ikematsu S, Iruela-Arispe ML, John A, Jürgen Schymeinsky, Karin Scharffetter-Kochanek, Kreis C, Kullander K, Liu XH, Loukinova E, Matzner Y, Muramaki M, Niiro H, Oda N, Pertovaara L, Ramchandran R, Roberts AB, Ruth Schruefer, Sang QX, Sato W, Scapini P, Scharffetter-Kochanek K, Schruefer R, Sehgal I, Semenza GL, Shapiro SD, Silke Sulyok, Takada T, Takada T, Tasiemski A, Thorsten Peters, Triebel S, Walzog B, Wang SC, Willeke T, Yoshida S   +55 more
core   +1 more source

Fluorescein angiography compared to three-dimensional measurements by the retinal thickness analyzer in classic choroidal neovascularization [PDF]

, 2007
Purpose: To compare and correlate imaging of classic subfoveal choroidal neovascularization (CNV) with noninvasive 3-dimensional imaging by the retinal thickness analyzer (RTA) to conventional fluorescein angiography (FA).
Kampik, Anselm, Neubauer, A. S., Rombold, F., Strauss, R. W.   +3 more
core   +1 more source