Results 111 to 120 of about 35,226 (335)

Management of Choroidal Neovascularization Secondary to Pathological Myopia

Asia-Pacific Journal of Ophthalmology, 2014
Choroidal neovascularization (CNV) secondary to pathological myopia is an important cause of significant visual impairment in young adults. High myopia is particularly prevalent in Asian population. New scientific contributions have been made to the understanding of high myopia and myopic CNV.
Mary, Ho, David T L, Liu, Alvin L, Young, Dennis S C, Lam   +3 more
openaire   +2 more sources

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

Intravitreal aflibercept for the treatment of choroidal neovascularization associated with pathologic myopia: a pilot study

Clinical Ophthalmology, 2016
Andrii R Korol, Oleg S Zadorozhnyy, Volodymyr O Naumenko, Taras B Kustryn, Nataliya V Pasyechnikova The Filatov Institute of Eye Diseases and Tissue Therapy of the National Academy of Medical Sciences of Ukraine, Odessa, Ukraine Purpose: To determine ...
Korol AR, Zadorozhnyy OS, Naumenko VO, Kustryn TB, Pasyechnikova NV   +4 more
doaj  

Use of ranibizumab for the treatment of subretinal neovascularization in pathologic myopia: a prospective study

Journal of Ophthalmology, 2016
Purpose: To determine the efficacy of ranibizumab as a treatment for subretinal neovascularization (SRNV) in pathologic myopia. Materials and Methods: This was an uncontrolled, prospective cohort study, involving 66 pathologic myopic eyes (65 patients)
О.M. Blavatska, T.B. Kustry, A.R. Korol
doaj   +1 more source

Mixed origin of neovascularization of human endometrial grafts in immunodeficient mouse models [PDF]

, 2009
peer reviewedBACKGROUND: In vivo mouse models have been developed to study the physiology of normal and pathologic endometrium. Although angiogenesis is known to play an important role in endometrial physiology and pathology, the origin of neovasculature
A. Beliard, Abulafia, Asahara, Becker, BRUNER-TRAN, C. Galant, Critchley, Debbage, Di Carlo, Donnez, E. Marbaix, Eggermont, F. Frankenne, Fraser, Galili, Galili, Gargett, Gordon, Grummer, Hickey, Hull, J.-M. Foidart, Jaffe, Kawashima, KRIKUN, M. Nisolle, M.-L. Alvarez Gonzalez, McCluggage, Mints, Murphy, Nap, Nisolle, Pe a, Risau, Rydberg, Saito, Smith, Story, Van Cauwenberge, Zeng   +39 more
core   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Intravitreal ranibizumab (Lucentis®) for the treatment of myopic choroidal neovascularization [PDF]

, 2018
Background: Macular choroidal neovascularization (CNV) is one of the most vision-threatening complications of myopia, which can lead to severe vision loss.
Ambresin, Aude, Konstantinidis, Lazaros, Mantel, Irmela, Pournaras, Jean-Antoine, Zografos, Leonidas   +4 more
core  

Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis [PDF]

, 2016
Age-related decreases in autophagy contribute to the progression of age-related macular degeneration (AMD). We have now studied the interaction between autophagy impaired in retinal pigment epithelium (RPE) and the responses of macrophages.
Barba, Miriam Durazo, Chiu, Hsi An Amy, Copland, David A, Dick, Andrew David, Liu, Jian, Mack, Matthias, Mak, Ka Wang, Nicholson, Lindsay B, Theodoropoulou, Sofia   +8 more
core   +2 more sources

A Time‐Programmed Bilayer Wound Dressing for Dynamic Microenvironment Modulation and Full‐Thickness Regeneration in Diabetic Wounds

Advanced Science, EarlyView.
The Polyphenol+PDGF‐BB scaffold fabrication (Panel A) and its dual wound healing effects (Panel B: anti‐inflammation and accelerated tissue remodeling). ABSTRACT Chronic diabetic wounds suffer from dysfunctional repair programs due to accumulated advanced glycation end products (AGEs) and persistent inflammation in hyperglycemic microenvironments ...
Lei Yi, Wanqian Li, Ying Duanmu, Zihan Zhang, Shixuan Chen, Shichu Xiao, Lei Du, Miaomiao Wei   +7 more
wiley   +1 more source

Two-year outcomes of intravitreal bevacizumab for choroidal neovascularization associated with a dome-shaped macula in pathologic myopia [PDF]

, 2016
Ji Hwan Lee, S C Lee, Seonghee Choi, Hyoung Jun Koh, Sung Soo Kim, Christopher Seungkyu Lee   +5 more
openalex   +1 more source