Results 271 to 280 of about 26,345 (302)

Choroidal neovascularization in pathological myopia

Progress in Retinal and Eye Research, 2012
Myopic choroidal neovascularization (CNV) is one of the leading causes of visual impairment worldwide. The clinical and socioeconomic impact of myopic CNV in Asian countries is particularly significant due to rising trend in the prevalence and severity of pathological myopia.
Kumari, Neelam, Chiu Ming Gemmy, Cheung, Kyoko, Ohno-Matsui, Timothy Y Y, Lai, Tien Y, Wong   +4 more
openaire   +2 more sources

RhoA/ROCK Signaling Is Involved in Pathological Retinal Neovascularization

Journal of Vascular Research, 2023
Objective: The aim of the study was to evaluate the effect of the RhoA/ROCK inhibitor Fasudil on retinal neovascularization (NV) in vivo and angiogenesis in vitro. Methods: C57BL/6 was used to establish an OIR model. First, RhoA/ROCK expression was first examined and compared between OIR and healthy controls. Then, we evaluated the effect of Fasudil on
Fen, Tang, Kongqian, Huang, Biyan, Peng, Wen, Deng, Ning, Su, Fan, Xu, Mingyuan, Zhang, Haibin, Zhong   +7 more
openaire   +2 more sources

Roentgenology-pathology correlative study of neovascularity

American Journal of Roentgenology, 1976
In an attempt to evaluate the histologic picture of what is shown on angiograms as neovascularity, several benign and malignant tumors were examined. New vessels (neovascularity) are large capillaries or sinusoids, and neither contain smooth muscle in their walls. The walls may contain some fibrous connective tissue.
S L, Gammill, F H, Shipkey, E H, Himmelfarb, L S, Parvey, J G, Rabinowitz   +4 more
openaire   +2 more sources

53BP1 Deficiency Promotes Pathological Neovascularization in Proliferative Retinopathy

Thrombosis and Haemostasis, 2019
AbstractThe replication stress inflicted on retinal endothelial cells (ECs) in the context of hypoxia-induced pathological neovascularization during proliferative retinopathy is linked with activation of the deoxyribonucleic acid (DNA) repair response.
Troullinaki, María, García-Martín, Rubén, Sprott, David, Klotzsche-von Ameln, Anne, Grossklaus, Sylvia, Mitroulis, Ioannis, Chavakis, Triantafyllos, Economopoulou, Matina   +7 more
openaire   +3 more sources

INTRAVITREAL RANIBIZUMAB FOR CHOROIDAL NEOVASCULARIZATION COMPLICATING PATHOLOGIC MYOPIA

Retina, 2010
The purpose of this study was to evaluate the efficacy of intravitreal injections of ranibizumab in choroidal neovascularization secondary to pathologic myopia.A prospective case series of 32 eyes of 32 patients affected with choroidal neovascularization secondary to pathologic myopia treated by intravitreal injections of ranibizumab.
Lalloum F, Souied EH, Bastuji Garin S, Puche N, QUERQUES , GIUSEPPE, Glacet Bernard A, Coscas G, Soubrane G, Leveziel N.   +8 more
openaire   +2 more sources

Characteristics of Periconus Choroidal Neovascularization in Pathologic Myopia

American Journal of Ophthalmology, 2011
To examine the clinical characteristics of periconus choroidal neovascularizations (CNVs) in eyes with pathologic myopia.Retrospective observational case series.We reviewed the medical records of 260 eyes of 254 patients with a myopic CNV and selected those with a periconus CNV.
Natsuko, Nagaoka, Noriaki, Shimada, Wakako, Hayashi, Kengo, Hayashi, Muka, Moriyama, Takeshi, Yoshida, Takashi, Tokoro, Kyoko, Ohno-Matsui   +7 more
openaire   +2 more sources

PATHOLOGY BEYOND NEOVASCULARIZATION

Retina, 2009
Control of choroid neovascularization may be important but insufficient to preserve long-term vision threatened by age-related macular degeneration. A retrospective analysis of patients who were early participants in anti-vascular endothelial growth factor studies, other pathologic processes, particularly fibrosis and atrophy, have participated in ...
openaire   +2 more sources

LACQUER CRACK FORMATION AND CHOROIDAL NEOVASCULARIZATION IN PATHOLOGIC MYOPIA

Retina, 2008
To clarify the characteristics of choroidal neovascularization (CNV) due to myopic CNV (mCNV) and the relation to lacquer crack (LC) formation.Thirty-seven eyes with mCNV underwent fluorescein angiography (FA) and indocyanine green angiography (ICGA) using Heidelberg Retina Angiograph 2 (HRA2; Heidelberg, Germany). mCNV was detected by FA and ICGA; LCs
Yasushi, Ikuno, Kaori, Sayanagi, Kaori, Soga, Miki, Sawa, Fumi, Gomi, Motokazu, Tsujikawa, Yasuo, Tano   +6 more
openaire   +2 more sources

Pathology of plaque haemorrhage and neovascularization of coronary artery

Journal of Cardiovascular Medicine, 2012
Intraplaque haemorrhage (IPH) is thought to play crucial roles in plaque progression and plaque rupture, resulting in acute coronary syndromes, which are the leading causes of morbidity and mortality in the developed countries. IPH is a common finding in atherosclerotic plaques.
Takahide, Kodama, Nupoor, Narula, Manuela, Agozzino, Eloisa, Arbustini   +3 more
openaire   +2 more sources

The pathology of abortive neovascular outgrowths from the retina

Graefe's Archive for Clinical and Experimental Ophthalmology, 1992
Seven abortive neovascular outgrowths (ANVOs) from diabetic retinas were obtained for examination either by biopsy during pars plana vitrectomy (2) or after discovery within enucleated globes (5). Scanning and electron microscopical, histochemical, immunohistochemical and retinal digest techniques were used.
P, Hiscott, R J, Cooling, P, Rosen, A, Garner   +3 more
openaire   +2 more sources