Results 1 to 10 of about 105,382 (219)

Integrating nociplastic pain into neuropathic pain framework: a proposal for a revised classification [PDF]

open access: yesFrontiers in Pain Research
From an etiological perspective, the International Association for the Study of Pain (IASP) classifies pain into three categories: nociceptive pain (NcP), neuropathic pain (NeP), and nociplastic pain (NpP).
Katsuhiro Toda
doaj   +2 more sources

The Crimean Tatars in the socio-economic processes in the Crimean ASSR (20–30 years of the XX century) [PDF]

open access: yesКрымское историческое обозрение, 2021
The article analyzes the relationship between the measures of the new economic policy and social processes in the Crimean ASSR. The NEP of 1920 was supposed not only to destroy economy, but also to form a national proletariat in the republic. The Crimean
Grigorii Kondratjuk
doaj   +1 more source

NEP-Score Thresholds Predict Survival of Patients With Bronchial Carcinoids

open access: yesFrontiers in Endocrinology, 2021
Survival prognostic markers are extremely needed to better define therapeutic strategies in patients with bronchial carcinoids (BC). We aim to verify the applicability of the NEP-Score in a homogeneous BC cohort and identify a derivative prognostic ...
Irene Gagliardi   +10 more
doaj   +1 more source

Intracranial injection of AAV expressing NEP but not IDE reduces amyloid pathology in APP+PS1 transgenic mice. [PDF]

open access: yesPLoS ONE, 2013
The accumulation of β-amyloid peptides in the brain has been recognized as an essential factor in Alzheimer's disease pathology. Several proteases, including Neprilysin (NEP), endothelin converting enzyme (ECE), and insulin degrading enzyme (IDE), have ...
Nikisha Carty   +8 more
doaj   +1 more source

Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model

open access: yesStem Cells International, 2021
Alzheimer’s disease (AD) animal studies have reported that mesenchymal stem cells (MSCs) have therapeutic effects; however, clinical trial results are controversial. Neprilysin (NEP) is the main cleavage enzyme of β-amyloid (Aβ), which plays a major role
HyeJu Jeong   +7 more
doaj   +1 more source

Neprilysin as a Biomarker: Challenges and Opportunities

open access: yesCardiac Failure Review, 2020
Neprilysin (NEP) inhibition is a successful novel therapeutic approach in heart failure with reduced ejection fraction. Assessing individual NEP status might be important for gathering insights into mechanisms of disease and optimising individualised ...
Noemi Pavo   +4 more
doaj   +1 more source

Bolometer Detector Modeling and its Performance Indexes [PDF]

open access: yesEngineering and Technology Journal, 2012
Bolometer detector is one of thermal detectors. In this research the essential concepts and parameters are included which cover the main types of bolometer detectors.
Mehdi Munshid Shellal
doaj   +1 more source

Educational training of militiamen of the Central Chernozem region in the early 1920s

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2023
Importance. The emergence and development of the system of professional police education in Soviet Russia in the first years after the October Revolution is considered. The relevance of the research lies in the possibility of using some approaches to the
E. A. Zverkov, N. M. Savitskiy
doaj   +1 more source

Ekaterinburg (Sverdlovsk) During NEP Years: Organization of City Government System

open access: yesНаучный диалог, 2023
The article discusses the activities of various levels of government structures (city council, gubernatorial, district and regional executive and party bodies) in managing EkaterinburgSverdlovsk during the NEP years.
S. V. Vorobyov
doaj   +1 more source

Intramolecular interaction of NEP regulated by CRM1 ensures the unidirectional transport of M1 for the nuclear export of influenza viral ribonucleoprotein

open access: yesFrontiers in Virology, 2023
IntroductionThe influenza virus genome consists of single-stranded RNAs and forms viral ribonucleoprotein (RNP) complexes. After viral genome replication in the nucleus, the viral RNP interacts with viral protein M1.
Mikako Hirohama   +7 more
doaj   +1 more source

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