Results 11 to 20 of about 1,127 (87)

Prognostic value of kappa free light chain index in patients with primary progressive multiple sclerosis [PDF]

Frontiers in Immunology
BackgroundThe kappa free light chain (κ-FLC) index is a well-established biomarker in multiple sclerosis (MS). While the prognostic value of the κ-FLC index has been demonstrated in early relapsing–remitting MS, its prognostic value in primary ...
Martin Schmidauer, Klaus Berek, Michael Auer, Gabriel Bsteh, Gabriel Bsteh, Paola Cavalla, Franziska Di Pauli, Massimiliano Di Filippo, Florian Deisenhammer, Andreja Emeršič, Andreja Emeršič, Fabian Föttinger, Lorenzo Gaetani, Michaela Hassler, Nik Krajnc, Nik Krajnc, Dejan Milosavljevic, Markus Ponleitner, Markus Ponleitner, Thor Petersen, Stefan Presslauer, Igal Rosenstein, Uroš Rot, Uroš Rot, Caroline Winther Tørring, Domizia Vecchio, Marco Vercellino, Tobias Zrzavy, Tobias Zrzavy, Anne Zinganell, Janette Walde, Harald Hegen   +31 more
doaj   +2 more sources

A Critical Review on the Standardization and Quality Assessment of Nonfunctional Laboratory Tests Frequently Used to Identify Inborn Errors of Immunity

Frontiers in Immunology, 2021
Inborn errors of immunity (IEI), which were previously termed primary immunodeficiency diseases, represent a large and growing heterogeneous group of diseases that are mostly monogenic.
Sandro Félix Perazzio, Sandro Félix Perazzio, Patricia Palmeira, Dewton Moraes-Vasconcelos, Andréia Rangel-Santos, João Bosco de Oliveira, Luis Eduardo Coelho Andrade, Luis Eduardo Coelho Andrade, Magda Carneiro-Sampaio, Magda Carneiro-Sampaio   +9 more
doaj   +1 more source

Angioedema Without Wheals: Challenges in Laboratorial Diagnosis

Frontiers in Immunology, 2021
Angioedema is a prevailing symptom in different diseases, frequently occurring in the presence of urticaria. Recurrent angioedema without urticaria (AE) can be hereditary (HAE) and acquired (AAE), and several subtypes can be distinguished, although ...
Anete S. Grumach, Camila L. Veronez, Camila L. Veronez, Dorottya Csuka, Henriette Farkas   +4 more
doaj   +1 more source

Evaluation of a new ELISA assay for monoclonal free‐light chain detection in patients with cardiac amyloidosis

eJHaem, 2022
The causal protein of amyloid light‐chain (AL) amyloidosis is a monoclonal immunoglobulin free light chain (mFLC), which must be quantified in the serum for patient diagnosis and monitoring.
Hajer Abroud, Asma Beldi‐Ferchiou, Vincent Audard, François Lemonnier, Fabien Le Bras, Karim Belhadj, Anissa Moktefi, Elsa Poullot, Khalil El Karoui, Jehan Dupuis, Alizée Maarek, Louise Roulin, Marie‐Hélène Delfau‐Larue, Silvia Oghina, Mounira Kharoubi, Mélanie Bézard, Amira Zaroui, Thibaud Damy, Valérie Molinier‐Frenkel   +18 more
doaj   +1 more source

Assessment of Intrathecal Free Light Chain Synthesis: Comparison of Different Quantitative Methods with the Detection of Oligoclonal Free Light Chains by Isoelectric Focusing and Affinity-Mediated Immunoblotting. [PDF]

PLoS ONE, 2016
We aimed to compare various methods for free light chain (fLC) quantitation in cerebrospinal fluid (CSF) and serum and to determine whether quantitative CSF measurements could reliably predict intrathecal fLC synthesis.
David Zeman, Pavlína Kušnierová, Zdeněk Švagera, František Všianský, Monika Byrtusová, Pavel Hradílek, Barbora Kurková, Olga Zapletalová, Vladimír Bartoš   +8 more
doaj   +1 more source

Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction

Arquivos Brasileiros de Cardiologia, 2003
OBJECTIVE: To evaluate the performance of the turbidimetric method of C-reactive protein (CRP) as a measure of low-grade inflammation in patients admitted with non-ST elevation acute coronary syndromes (ACS).
Luis C. L. Correia, José C. Lima, Gary Gerstenblith, Luis P. Magalhães, Agnaluce Moreira, Octávio Barbosa Jr., Juliana Dumet, Luiz Carlos S. Passos, Argemiro D'Oliveira Júnior, José Péricles Esteves   +9 more
doaj   +1 more source

Estudo comparativo entre agregação plaquetária por turbidimetria e impedância elétrica em pacientes sob terapia antiplaquetária à base de ácido acetilsalicílico Comparative study of platelet aggregation by turbidimetric and impedance methods in patients under acetylsalicylic acid antiplatelet therapy

Revista Brasileira de Hematologia e Hemoterapia, 2010
INTRODUÇÃO: A hiperagregação (agregação excessiva) das plaquetas pode causar a formação de um trombo e a posterior oclusão dos vasos sanguíneos levando à isquemia.
Leonardo Lorenzo da Silva, Elbio Antonio D'Amico   +1 more
doaj   +1 more source

Correlation study on cystatin C and ischemic stroke

Chinese Journal of Contemporary Neurology and Neurosurgery, 2013
Objective To investigate the relationship between serum cystatin C (Cys C) and patients with acute ischemic stroke. Methods The clinical and laboratory data of 115 patients with acute ischemic stroke and 110 controls were recorded and analyzed.
Rong-bo CHEN, Wen-jie CHEN, Xuan ZHENG
doaj  

Performance Evaluation of Serum Free Light Chain Analysis: Nephelometry vs Turbidimetry, Monoclonal vs Polyclonal Reagents.

American journal of clinical pathology, 2017
Free light chain (FLC) measurement gained a lot of interest for diagnostic workup of monoclonal gammopathy.We evaluated the performance of turbidimetric polyclonal Freelite (The Binding Site, Birmingham, UK) assays on Cobas 6000 (Roche Diagnostics, Rotkreuz, Switzerland) and nephelometric monoclonal N Latex (Siemens Healthcare Diagnostics, Marburg ...
Messiaen, Anne-Sophie, De Sloovere, Maxime M. W., Claus, Paul-Emile, Vercammen, Martine, Van Hoovels, Lieve, Heylen, Olivier, Debrabandere, Johan, Vanpoucke, Hilde, De Smet, Dieter   +8 more
openaire   +2 more sources

Diagnostic value of kappa free light chain index in patients with primary progressive multiple sclerosis - a multicentre study. [PDF]

Front Immunol, 2023
Hegen H, Berek K, Cavalla P, Christiansen M, Emeršič A, Di Filippo M, Gaetani L, Hassler M, Leurs C, Milosavljevic D, van Pesch V, Petersen T, Presslauer S, Rosenstein I, Rot U, Schnabl C, Teunissen C, Vecchio D, Vercellino M, Deisenhammer F.   +19 more
europepmc   +1 more source