Results 111 to 120 of about 56,752 (229)

Tislelizumab Combined With Axitinib in Neoadjuvant Treatment of Locally Advanced Clear Cell Renal Cell Carcinoma: A Single‐Center, Phase II Clinical Study

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Tislelizumab plus axitinib as neoadjuvant therapy for locally advanced clear cell renal cell carcinoma (ccRCC) demonstrated substantial efficacy and acceptable safety in a single‐center prospective single‐arm study. The objective response rate reached 55%, one patient attained pathological complete response, and patients with RTK/RAS pathway ...
Wenjin Yang   +8 more
wiley   +1 more source

Preoperative VEGFR‐TKI Plus ICI Therapy Facilitates 3D‐Guided Cytoreductive Nephron‐Sparing Surgical Feasibility and Immune Remodeling in Advanced Renal Cell Carcinoma

open access: yesMed Research, Volume 2, Issue 1, Page 89-105, March 2026.
Preoperative VEGFR‐TKI plus ICI therapy in advanced ccRCC normalizes tumor vasculature, enhances CD8⁺ T/B cell infiltration, and promotes TLS maturation, leading to profound tumor microenvironment remodeling. These immunologic changes improve the feasibility of 3D reconstruction‐guided robotic cytoreductive nephron‐sparing surgery, resulting in reduced
Wenhao Xu   +10 more
wiley   +1 more source

Advances and Prospects of Stereotactic Radiosurgery and Stereotactic Ablative Body Radiotherapy: Evolving Paradigms in Precision Oncology

open access: yesMed Research, Volume 2, Issue 1, Page 157-180, March 2026.
The graphical abstract outlines the progressive development and impact of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Technological Evolution illustrates the transition from brachytherapy with single‐dose, LDR/HDR schedules to fractionated radiotherapy, three‐dimensional conformal radiotherapy (3DCRT) and Gamma Knife ...
Jing Zhang   +10 more
wiley   +1 more source

Three-Dimensional Virtual Model for Robot-Assisted Partial Nephrectomy (RAPN): Development of Study Protocol for Evaluation of the Learning Curve to Optimize the Precision and Accuracy of the 3D Imaging

open access: yesResearch and Reports in Urology
Paolo Traverso,1,2,* Guglielmo Mantica,1,2,* Veronica Giasotto,2 Carlo Terrone1,2 1Department of Surgical and Diagnostic Integrated Sciences (DISC), University of Genova, Genova, Italy; 2IRCCS Policlinico San Martino, Genova, Italy*These ...
Traverso P   +3 more
doaj  

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem   +9 more
wiley   +1 more source

Beyond the Norm: Atypical Manifestations of Aspergillosis

open access: yesRespirology Case Reports, Volume 14, Issue 3, March 2026.
We describe a rare case of Aspergillus infection presenting as a chest mass, underscoring the diagnostic challenges of fungal diseases in immunocompromised patients and highlighting the importance of considering unusual manifestations in clinical practice.
Leila Zahiri   +5 more
wiley   +1 more source

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