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Global patterns and trends in kidney cancer incidence and mortality
International Journal of Cancer, Volume 159, Issue 1, Page 67-77, 1 July 2026.What's New?
Decreasing mortality from kidney cancer in developed countries contrasts with persistently high or rising mortality in less‐developed regions. Factors underlying this widening gap remain incompletely understood. Using GLOBOCAN 2022 data, the present study examined patterns in kidney cancer incidence and mortality worldwide and the relation ...Anton Barchuk, Jerome Vignat, Kari A. O. Tikkinen, Ahmedin Jemal, Freddie Bray, Ariana Znaor +5 morewiley +1 more sourceMalignant/Sarcomatous Transformation of Mixed Epithelial and Stromal Tumor of the Kidney: A Case Report
IJU Case Reports, Volume 9, Issue 4, July 2026.ABSTRACT Introduction
Malignant transformation of mixed epithelial and stromal tumors of the kidney (MESTK) is extremely rare. Case Presentation
A 39‐year‐old man with gross hematuria was suspected to have renal cell carcinoma, measuring 13 cm in diameter. No distant metastases were observed.Kentaro Arinami, Kozue Ito, Go Hasegawa, Yurie Takizawa, Yohei Ikeda, Noboru Hara, Tsutomu Nishiyama +6 morewiley +1 more sourceBelzutifan for Metastatic TFE3‐Rearranged Renal Cell Carcinoma With Pulmonary Metastases: A Case Report
IJU Case Reports, Volume 9, Issue 4, July 2026.ABSTRACT Introduction
Belzutifan is effective in patients with previously treated advanced clear cell renal cell carcinoma. However, evidence for its use in non‐clear cell renal cell carcinoma remains limited. Case Presentation
A 33‐year‐old Japanese woman underwent total nephrectomy for a 10‐cm renal tumor with lung metastases.Kazutaka Nakamura, Akihiro Kumono, Yuki Kobari, Atsuko Seki, Takayuki Nakayama, Hironori Fukuda, Kazuhiko Yoshida, Junpei Iizuka, Yoji Nagashima, Toshio Takagi +9 morewiley +1 more sourceSignificant Response to Nivolumab Plus Ipilimumab in Metastatic Mucinous Tubular and Spindle Cell Carcinoma: A Case Report
IJU Case Reports, Volume 9, Issue 4, July 2026.ABSTRACT Introduction
Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare renal cell carcinoma subtype that is typically indolent but may exhibit aggressive behavior. No standard systemic therapy has been established for metastatic MTSCC. Case Presentation
A 71‐year‐old woman underwent retroperitoneoscopic radical left nephrectomy for MTSCC ...Sho Shimasaki, Shinkuro Yamamoto, Mitsuko Iguchi, Erika Yamashita, Kaya Atagi, Yuhei Shiba, Satoshi Fukata, Hirofumi Satake, Takashi Karashima, Keiji Inoue +9 morewiley +1 more sourceClinical Utility of 68Ga‐DOTATOC Positron Emission Tomography/Computed Tomography in Evaluating Metastatic Lesions of Clear Cell Renal Cell Carcinoma: A Case Report
IJU Case Reports, Volume 9, Issue 4, July 2026.ABSTRACT Introduction
68Ga‐DOTATOC positron emission tomography/computed tomography (PET/CT) targets somatostatin receptors (SSTRs) and is an established molecular imaging modality for neuroendocrine tumors (NETs). Although SSTR expression has been reported in renal cell carcinoma (RCC), its clinical utility remains unclear. Case Presentation
A 76‐year‐Yuta Mine, Toru Sakatani, Sho Koyasu, Takashi Ogata, Yuki Teramoto, Akio Sakamoto, Takashi Mizowaki, Yuji Nakamoto, Takashi Kobayashi, Takayuki Goto +9 morewiley +1 more sourceTailored Vascular Approach in Robot‐Assisted Nephroureterectomy for a Horseshoe Kidney: A Case Report
IJU Case Reports, Volume 9, Issue 4, July 2026.ABSTRACT Introduction
A horseshoe kidney is a rare congenital anomaly with complex vascular variations that increase surgical difficulty. Few reports have specifically addressed the vascular approaches in robot‐assisted surgery. Case Presentation
A man in his 70s was diagnosed with right ureteral urothelial carcinoma in a horseshoe kidney. Preoperative Takanari Kambe, Yosuke Shimizu, Hajime Yoshida, Koken Hayashi, Shotaro Hatano, Tomoaki Okada, Kenji Mitsumori, Hiroyuki Onishi +7 morewiley +1 more sourceASPSCR1: TFE3 Fusion‐Positive Epithelioid Angiomyolipoma/PEComa Lacking Melanocytic Markers: A Case Report
IJU Case Reports, Volume 9, Issue 4, July 2026.ABSTRACT Introduction
Epithelioid angiomyolipoma is a rare perivascular epithelioid cell tumor subtype with malignant potential. Its morphology mimics renal cell carcinoma, posing diagnostic challenges. Half of these cases harbor TSC1/TSC2 alterations, and a small subset features TFE3 rearrangements, mutually exclusive of TSC mutations.Yuka Kondo, Yoji Nagashima, Kenji Zennami, Megumi Sato, Sayaka Sumiyoshi, Akihiko Sugimoto, Madoka Isomura, Kiyoshi Takahara, Sachiko Minamiguchi +8 morewiley +1 more sourceIatrogenic ureteric injuries after abdominal surgery: a systematic review and meta‐regression from the European Association of Urology Endourology Section
BJU International, Volume 138, Issue 1, Page 45-56, July 2026.Objective
To systematically evaluate management strategies and associated outcomes of iatrogenic ureteric injuries, focusing on clinical success, renal unit loss, and the need for subsequent endoscopic or reconstructive procedures. Patients and Methods
A pre‐registered protocol (CRD420251184018) guided a comprehensive search of PubMed and EMBASE ...Pietro Scilipoti, Nicola Nannola, Federico Zorzi, Carlos Gonzalez Gonzalez, Marie Chicaud, Luigi Candela, Stefano Moretto, Carlotta Nedbal, Tzevat Tefik, Luca Villa, Eugenio Ventimiglia, Andrea Salonia, Alberto Briganti, Francesco Montorsi, Bhaskar K. Somani, Steeve Doizi, Olivier Traxer, Frederic Panthier +17 morewiley +1 more sourceOutcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative
Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.ABSTRACT Purpose
Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods
A multicenter retrospective review was performed Hannah N. Rinehardt, Elisabeth T. Tracy, Anghela Paredes, Catherine Beckhorn, Harold J. Leraas, Joseph Fusco, Katlyn G. McKay, Nelly‐Ange T. Kontchou, Zachary J. Kastenberg, David W. Hoyt, Jonathan Roach, Emily K. Myers, Nicholas G. Cost, Bhargava Mullapudi, Charles R. Marchese, Amanda R. Jensen, Timothy B. Lautz, Michela Carter, Roshni Dasgupta, John Lundstedt, Joseph G. Brungardt, Lindsay Talbot, Andrew M. Davidoff, Andrew J. Murphy, Jennifer H. Aldrink, Sara Mansfield, Nelson Piche, Annie Le‐Nguyen, Dave R. Lal, Brian T. Craig, Jennifer M. Schuh, Barrett P. Cromeens, Sindhu Mannava, Shannon Castle, Adriana Lopez, Kelsey Mello, Joshua Short, Robin T. Petroze, Shay Rajavel, Grace R. Thompson, Peter Mattei, David H. Rothstein, Elizabeth Fialkowski, Kathryn Fowler, Nathan Martchenke, Barrie S. Rich, Richard D. Glick, Erin G. Brown, Kathleen Doyle, Paige Abril, Natashia Seemann, Jacob Davidson, Claire A. Wilson, Hau D. Le, Devashish Joshi, Michael Stellon, Tamer Ahmed, Alexandra Dimmer, Peter F. Ehrlich, Maya Hammoud, Keyonna Williams, Christa N. Grant, Merit Gorgy, Stephanie F. Polites, Julia Debertin, Danielle B. Cameron, Alyssa Stetson, Eugene S. Kim, William G. Lee, Aaron Barkhordar, Mary Austin, Brian A. Coakley, Anastasia Kahan, Joseph T. Murphy, Michael Pitonak, Chloé Boehmer, Marcus M. Malek +76 morewiley +1 more sourceFASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure
Advanced Science, Volume 13, Issue 34, 19 June 2026.Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu +14 morewiley +1 more source