Results 111 to 120 of about 86,281 (261)

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

Experimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris, Anton Trask‐Marino, Alemayehu Jufar, Ashenafi H. Betrie, Adam Southon, Sally G. Hood, Rinaldo Bellomo, Abraham H. Hulst, Clive N. May, Connie P. C. Ow, Yugeesh R. Lankadeva   +10 more
wiley   +1 more source

Validation of a novel robotic-assisted partial nephrectomy surgical training model

, 2012
What's known on the subject? and What does the study add? One area of particular growth for robotic surgery has been partial nephrectomy. Despite a perceived notion that robotic-assisted partial nephrectomy is more easily adaptable compared to ...
Patil, Mukul B, Aron, Monish, Gill, Inderbir S, Huang, Eric, Zehnder, Pascal, Ng, Casey K, Desai, Mihir M, Hung, Andrew J   +7 more
core   +1 more source

Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells

Experimental Physiology, EarlyView.
ABSTRACT Acute kidney injury (AKI) is a global health problem with significant long‐term harm if the prognosis is poor. Dual‐specificity phosphatase 2 (DUSP2) is involved in key regulatory pathways in several disease processes, but its function in renal pathophysiology is unclear.
Xueqian Chu, Songmin Xue, Lanyan Lin, Xuan Huang, Sisi Chen, Wulaer Adeli, Zulibiya Tuohetiyaer, Suhua Li, Chen Lu   +8 more
wiley   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

S14G‐humanin attenuates renal ischaemia–reperfusion injury, potentially through activation of STAT3 and ERK1/2 signalling pathways in rats

Experimental Physiology, EarlyView.
Abstract Renal ischaemia–reperfusion (I/R) injury leads to acute tubular necrosis and renal failure, triggering pathological mechanisms including inflammation, reactive oxygen species generation, apoptosis and mitochondrial dysfunction. The mitochondrial peptide humanin (HN), known to possess anti‐apoptotic and anti‐inflammatory properties, has been ...
Leyla Abueid, Ahmet Faruk Torun, Ezgi Golal, Nuray Acar, Filiz Basrali   +4 more
wiley   +1 more source

Systematic review of surgery of solitary metastasis post nephrectomy and its survival.

, 2018
Renal cell Carcinoma is the twelfth most common cancer worldwide with 338000 cases diagnosed in 2012. The recurrence rates after nephrectomy for RCC is about 20-30% and about 40% eventually dying from the cancer progression.
Seshadri Sriprasad, Sanjeev Madaan, Jaisimha Abbaraju, Lava Krishna Kannappa, Khalid Hureibi   +4 more
core  

Nephrogenic Rests/Nephroblastomatosis in Patients With Unilateral Wilms Tumor Are Not Associated With an Increased Risk of Relapse: An Analysis of Patients Treated on the SIOP‐WT‐2001 Protocol in the SIOP‐UK‐CCLG and SIOP‐GPOH Studies (2001–2022)

Pediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Introduction Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misunderstanding of their diagnostic criteria and terminology.
Gordan M. Vujanić, Rhoikos Furtwängler, Tanzina Chowdhury, Christian Vokuhl, Jenny Wegert, Norbert Graf   +5 more
wiley   +1 more source

Fibromyxoid Nephrogenic Adenoma Mimicking Renal Cell Carcinoma: A Diagnostic Pitfall in Fine‐Needle Aspiration Cytology

Diagnostic Cytopathology, Volume 54, Issue 10, Page E236-E239, October 2026.
ABSTRACT Nephrogenic adenoma (NA) is a benign lesion of the genitourinary tract that may mimic malignancy both clinically and histologically. The fibromyxoid variant (FMNA), characterized by spindled cells in myxoid stroma, presents additional diagnostic challenges due to its rarity and overlapping features with renal cell carcinoma (RCC).
Jodi Gedallovich, Adebola Adeniyi, Ankur R. Sangoi, Xiaohua Qian, Kelly Ernst   +4 more
wiley   +1 more source

Functional Advantages of Laparoscopic Live-Donor Nephrectomy Compared with Conventional Open-Donor Nephrectomy

, 1997
Live-donor kidney transplants accounted for only 27% of all kidney transplants performed in the United States in 1995. Prolonged hospitalization, pain, extended convalescence, and related socioeconomic concerns associated with traditional open-donor ...
Ann Morrison, Mary Jo Holochek, Louis R Kavoussi, Myrna Sroka, Lloyd E Ratner, Janet Hiller   +5 more
core   +1 more source

Kidney Structure and Blood Flow Predict Function and Enable Image‐Based eGFR With Non‐Contrast MRI

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Multiparametric renal MRI in healthy adults identified cortical thickness (r² = 0.38) and renal blood flow (r² = 0.29; both p < 0.001) as the strongest predictors of creatinine‐based eGFR. Together, these measures explained 47% of eGFR variability. Prospective validation demonstrated low bias (−4.9 to 3.4 mL/min/1.73 m²) and good accuracy (p30: 87%–92%)
Emily Powell, Corina Margain, Jiachen Wang, Joel Adler, Alexandra Clark, Adam Bush   +5 more
wiley   +1 more source