Results 41 to 50 of about 78,503 (261)

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Biofabrication of a Filtration Barrier by Integrating Electrospun Membranes and Flow in a Glomerular Co‐Culture

Advanced Healthcare Materials, EarlyView.
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni, Anna Rederer, Vladimir Stepanenko, Frank Würthner, Philipp Stahlhut, Jürgen Groll, Mario Schiffer, Taufiq Ahmad, Janina Müller‐Deile   +8 more
wiley   +1 more source

Renal artery aneurysm at a Nigerian tertiary centre: Case report and review of literature.

Nigerian Journal of Medicine, 2020
Renal artery aneurysms are rare urologic conditions, with rupture being the most feared complication. We discuss the management of two women with this disease at our center.
Rereloluwa Nicodemus Babalola, Stephen Odunayo Ikuerowo, Olufunmilade Akinfolarin Omisanjo, Abimbola Ayodeji Abolarinwa   +3 more
doaj   +1 more source

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

Advanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu, Xiumei Zhao, Maolin Zang, Huiyang Yuan, Xin Qin, Xiaofeng Li, Shuo Zhao, Ruirong Tan, Keqiang Yan, Li Liu, Yidong Fan, Ning Zhang, Benkang Shi, Bo Han, Shouzhen Chen   +14 more
wiley   +1 more source

Xanthogranulomatous pyelonephritis: Rare presentation of a rare disease

South Asian Journal of Cancer, 2013
Xanthogranulomatous pyelonephritis is a rare chronic renal infection of unknown pathogenesis characterized by replacement of renal parenchyma by lipid filled macrophages frequently associated with an enlarged, non-functioning kidney and an obstructing ...
Saifullah Khalid, Sufian Zaheer, Samreen Zaheer, Ibne Ahmad, Mohd Khalid   +4 more
doaj   +1 more source

Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice

Advanced Science, EarlyView.
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu, Kaiqiang Li, Huasong Liu, Aibo Xu, Zhewei Zhang, Yimin Yang, Xiaobo Lai, Ke Hao, Kui Fang, Zeyu Lai, Xiping Ou, Yuqun Cai, Zhen Wang, Keda Lu, Wanli Jiang   +14 more
wiley   +1 more source

Radiomics‐Based Unsupervised Clustering Identifies Subtypes Associated With Prognosis and Immune Microenvironment in Clear Cell Renal Cell Carcinoma: A Multicenter Study

Advanced Science, EarlyView.
This study developed an unsupervised radiomics system integrating CT imaging and multi‐omics data to stratify clear cell renal cell carcinoma into two subtypes with distinct clinical outcomes. Cluster 1 showed lower recurrence risk and active immunity, while Cluster 2 exhibited higher recurrence risk, enriched VHL/KDM5C mutations, immunosuppressive ...
Yusheng Guo, Bingxin Gong, Yi Li, Jie Lou, Shuai Shan, Xiaodong Zhang, Qiang Lu, Dongyong Zhu, Qing Sun, Lianwei Miao, Yuanxi Li, Yu‐Dong Zhang, Wei Tan, Lian Yang, Chuansheng Zheng   +14 more
wiley   +1 more source

Pseudoaneurysm after partial nephrectomy managed by selective angiographic embolization – a case report

Angiologia e Cirurgia Vascular
INTRODUCTION: Partial nephrectomy is considered the gold standard treatment for many renal tumors when technically feasible. Renal artery pseudoaneurysm and arteriovenous fistulas are rare life-threatening complications that occur more frequently after ...
Roberto Cunha, Manuel Silva, Pedro Sousa, Mafalda Correia, Isabel Vieira, Isabel Cássio, Nelson Oliveira, Emanuel Dias   +7 more
doaj   +1 more source

Comparison of three different techniques of extraction in laparoscopic donor nephrectomy

Indian Journal of Urology, 2013
Aim: We compare the outcome of three different methods of graft extraction after a laparoscopic donor nephrectomy. Materials and Methods: After a conventional five port laparoscopic donor nephrectomy, specimen was extracted through one of three ...
Kishore Thekke Adiyat, B K Tharun, Abijit Shetty, Srinivas Samavedi   +3 more
doaj   +1 more source

A five-year review of nephrectomies at the lagos state university teaching hospital (LASUTH) Ikeja Lagos

Nigerian Journal of Medicine, 2020
Background: Nephrectomies are performed for various reasons ranging from benign to malignant renal diseases. The surgical approach for a nephrectomy also varies with location.
Olufunmilade A Omisanjo, Olufemi O Ojewuyi, Omolara M Williams, Abimbola A Abolarinwa, Olufemi O Akinola, Adekunle A Adebayo, Stephen O Ikuerowo, Fatai A Balogun   +7 more
doaj   +1 more source