Results 41 to 50 of about 110,638 (255)

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Histopathology Analysis, Clinical Profile, and Indications of Graft Nephrectomy: Single-center Study

Indian Journal of Transplantation
Background: Renal transplantation is the preferred form of treatment in patients with end-stage renal disease. Despite potent immunosuppression, the patient can develop graft failure in early and late posttransplant period due to immune and nonimmune ...
Pallav Gupta, Tarun Kumar, Vinant Bhargava, Manish Malik, Anurag Gupta, Vaibhav Tiwari, Ashwani Gupta, Anil Kumar Bhalla, Devinder Singh Rana   +8 more
doaj   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Robot-assisted partial nephrectomy: Is it the future of kidney surgery? A comparison of nephron-sparing techniques in partial nephrectomy

Quality in Sport
Technological advancements are significantly transforming various medical fields, including urology. The increasing adoption of minimally invasive surgical techniques and robotic assistance is particularly impactful. Three partial nephrectomy techniques
Bartłomiej Ast, Igor Piotrowski, Krzysztof Dobrzeniecki   +2 more
doaj   +1 more source

Effects of Chronic Renal Failure on Surgical Outcomes of Laparoscopic Nephrectomy for Benign Diseases? A Comparative Study

Journal of Urological Surgery, 2020
Objective:The aim of this study was to compare surgical outcomes of laparoscopic nephrectomy (LN) for benign diseases in patients with chronic renal failure (CRF) undergoing hemodialysis with their non-CRF counterparts.Materials and Methods:A ...
Erkan Ölçücüoğlu, Muhammet İrfan Dönmez, Ahmet Murat Bayraktar   +2 more
doaj   +1 more source

Sonographic Diagnosis of an Intercostal Artery Pseudoaneurysm: A Case Report and Literature Review

Journal of Clinical Ultrasound, EarlyView.
A 63‐year‐old male presented to the emergency department after being found unconscious during a welfare check. Following a prolonged three‐month hospital admission, the patient developed left flank pain. Spectral Doppler ultrasound revealed a large isoechoic lesion with layering echoes, and spectral Doppler demonstrated bidirectional flow.
Aaditya P. Singh, Peter R. Coombs
wiley   +1 more source

Central Adrenal Insufficiency Developing After Right Partial Nephrectomy Involving Ectopic Adrenocortical Adenoma Mimicking Right Renal Carcinoma and a Retrospective Diagnosis of Adrenal Cushing's Syndrome: A Case Report. [PDF]

IJU Case Rep
ABSTRACT Introduction Ectopic adrenocortical adenomas that produce adrenal hormones and mimic renal cell carcinoma are extremely rare. Case Presentation A 49‐year‐old woman underwent partial nephrectomy of the upper pole of the kidney following a clinical diagnosis of renal cell carcinoma.
Arinami K, Kikuchi S, Ohara N, Takizawa Y, Ikeda Y, Ito K, Hasegawa G, Hara N, Nishiyama T.   +8 more
europepmc   +2 more sources

World Health Organization (WHO)/International Society of Urological Pathology (ISUP) grading in fine‐needle aspiration biopsies of renal masses [PDF]

, 2018
Background Utilization of fine‐needle aspiration (FNA) biopsy for the evaluation of renal masses has been increasing at our institution. At times diagnostic material on direct smears is superior to that in the cell block/core biopsy, therefore assigning
Al Nazer, Ball, Bishop, Blute, Campbell, Dagher, Delahunt, Delahunt, Fuhrman, Gilani, Halverson, Jewett, Leone, Marconi, Millet, Moch, Pambuccian, Richard, Richard, Schmidbauer, Yang   +20 more
core   +1 more source

Probiotic consumption reduces alveolar bone loss and kidney damage in pregnant rats with experimental periodontitis

Journal of Periodontology, EarlyView.
Abstract Background Bifidobacterium animalis subsp. lactis HN019 (B. lactis HN019) is a probiotic bacterial strain with immunomodulatory properties. Its benefits have been observed in healthy and systemically compromised animals with periodontitis (PD). Our objective was to investigate the local and systemic effects of the systemic administration of B.
Átila V. V. Nobre, Pedro H. F. Silva, Marina C. G. Del‐Arco, Raquel F. Gerlach, Rene S. Oliezer, José E. Tanus‐Santos, Luciene C. Figueiredo, Janaina S. A. M. Evangelista, Flávia A. C. Furlaneto, Michel R. Messora, Sérgio Luiz Salvador   +10 more
wiley   +1 more source