Results 111 to 120 of about 131,131 (300)

Clinical progress note: Mumps

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Mumps was a common childhood viral illness before the implementation of the measles, mumps, and rubella (MMR) vaccination in 1967. There was a significant decrease in mumps cases in the postvaccine era; however, there has been an increase in outbreaks in the United States over the past two decades.
Sarah Ludvigsen, Mati Segev
wiley   +1 more source

TRIM Expression and Its Association With Disease Activity in Systemic Lupus Erythematosus

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse manifestations, including rash, arthritis, and nephritis. Although autoantibodies are a key feature of SLE, their levels often poorly reflect disease severity, suggesting the involvement of additional contributing factors.
Ling‐Ying Lu   +8 more
wiley   +1 more source

Granzyme K: A new frontier in systemic lupus erythematosus

open access: yesRheumatology &Autoimmunity, EarlyView.
The role of Granzyme K in the pathogenesis of systemic lupus erythematosus and its clinical translational significance. Abstract Systemic lupus erythematosus (SLE) is a complex autoimmune disorder driven by dysregulated adaptive and innate immunity and aberrant complement activity.
Zhongyu Chen   +5 more
wiley   +1 more source

Role of MCP-1 as an inflammatory biomarker in nephropathy

open access: yesFrontiers in Immunology
The Monocyte chemoattractant protein-1 (MCP-1), also referred to as chemokine ligand 2 (CCL2), belongs to the extensive chemokine family and serves as a crucial mediator of innate immunity and tissue inflammation.
Yanlong Liu   +8 more
doaj   +1 more source

Evaluating Acute Interstitial Nephritis Rates in Renal Biopsies (Single Center Study) [PDF]

open access: yes, 2019
Aim:We aimed to evaluate the prevalence and clinicopathological features of acute interstitial nephritis in patients undergoing renal biopsy.Materials and Methods:A total of 1048 native kidney biopsies performed between 2010 and 2018 in the Nephrology ...
Zeki SOYPAÇACI, Uğur KORKMAZ
core  

Intersection of systemic lupus erythematosus and autoimmune thyroid disease: Shared pathophysiology, epidemiology, diagnosis, and management

open access: yesRheumatology &Autoimmunity, EarlyView.
A proposed mechanistic framework of systemic lupus erythematosus (SLE) and autoimmune thyroid disease (AITD) pathogenesis. In Stage 1, genetically susceptible individuals harbor risk variants within major histocompatibility complex (HLA) and non‐HLA loci that impair central and peripheral immune tolerance mechanisms within the thymic and peripheral ...
Elisa Elisa   +3 more
wiley   +1 more source

FGF23‐related hypophosphatemic rickets preceding the onset of systemic lupus erythematosus: A juvenile case

open access: yesClinical Case Reports
Key Clinical Message This case report describes the clinical course of a juvenile female with FGF23‐related hypophosphatemic rickets preceding the onset of SLE. Our study demonstrates the possibility of hypophosphatemic rickets as an early symptom of SLE.
Yoko tabei   +6 more
doaj   +1 more source

Integrative proteomic profiling of extracellular vesicle‐enriched preparations with machine learning identifies disease activity‐associated signatures linked to adverse pregnancy outcomes in systemic lupus erythematosus

open access: yesVIEW, EarlyView.
Integrating cross‐cohort extracellular vesicle proteomics with machine learning identifies a simplified protein signature (AGT, FETUB, SPP2, and FCN3) for adverse pregnancy outcome risk stratification in systemic lupus erythematosus, enabling precise disease‐activity discrimination beyond routine clinical assessment.
Weiwei Shi   +5 more
wiley   +1 more source

A Novel NPHP5 Gene Mutation in Three Siblings With Nephronophthisis Without Retinitis Pigmentosa: A Case Report

open access: yesCase Reports in Genetics
Nephronophthisis (NPHP) is a hereditary renal disorder characterized by the progression to end-stage renal disease (ESRD) at a young age. Our understanding of this disorder continues to improve as we identify more genes and gene variants associated with ...
Randah Abdullah Dahlan   +1 more
doaj   +1 more source

Health impacts of public pawnshops in Industrialising Tokyo

open access: yesAsia‐Pacific Economic History Review, EarlyView.
Abstract This study examines whether expanded credit access through low‐interest small loans relaxed liquidity constraints among poor households and improved early‐life health in industrialising Tokyo. Using ward‐level panel data for 1927–1935, this study shows that public pawnshop lending was associated with 4% and 5% reductions in infant and foetal ...
Tatsuki Inoue
wiley   +1 more source

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