Results 121 to 130 of about 12,991 (277)

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

گزارش 1 مورد نفريت ارثی نادر(سندرم Fechtner) [PDF]

, 2004
يک بيماری نادر اتوزومال غالب است که با مجموعه‌ای از علائم چشمی(کاتاراکت)، کاهش شنوايی عصبی، درگيری کليه(هماچوری تا نارسايی کليه)، انکلوزيون داخل گلبول سفيد و ماکروترومبوسيتوپنی شناخته می‌شود. بيمار معرفی شده در اين مقاله آقای 21 ساله‌ای بود که با تظاهرات
الهی, فاضل, ساوج, شکوفه, مهدوی, محمدرضا, نژادگشتی, حسین   +3 more
core  

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Retrospective study of mortality in Asiatic lions (Panthera leo persica) in the European breeding population between 2000 and 2014 [PDF]

, 2017
Acton, Banerjee, Banerjee, Bates, Buchanan, Clancy, Daunt, Depauw, Driscoll, Elliott, Elliott, Hope, Jonathan Williams, Junginger, Maia, Martínez, Meijer, Newkirk, Nic Masters, O'Brien, Olivia Metz, Ralls, Ralls, Rikke Kruse Nielsen, Rubin, Shangguan, Vercammen, Wielebnowski   +27 more
core   +2 more sources

Rehabilitation of young adults during renal replacement therapy in Europe: The presence of disabilities [PDF]

, 2017
The aim of this study was to analyse rehabilitation during RRT in 617 young adults from different European countries who started dialysis or transplantation before the age of 15 years. The data were derived from the EDTA Registry patient data files and a
Broyer, M., Brunner, F. P., Brynger, H., Ehrich, J. H. H., Fassbinder, W., Geerlings, W., Rizzoni, G., Selwood, N. H., Tufveson, G., Wing, A. J.   +9 more
core  

Discovery and validation of a urinary extracellular vesicle protein signature for the diagnosis of renal allograft fibrosis

Interdisciplinary Medicine, EarlyView.
Discovery and validation of a urinary extracellular vesicle protein signature for the diagnosis of renal allograft fibrosis. Abstract Interstitial fibrosis is the best indicator of irreversible or ongoing renal injury after kidney transplantation and faces considerable diagnostic challenges.
Wenxuan Zhao, Yang Xu, Yuewen Wang, Shihao Jin, Wenhui Wang, Zeming Yu, Yanwen Zhang, Yuxin Zhang, Deling Kong, Bing Wang, Zhenzhou Wu, Jie Zhao, Yuebing Wang   +12 more
wiley   +1 more source

Understanding hereditary diseases using the dog and human as companion model systems [PDF]

, 2007
Kate L. Tsai, Leigh Anne Clark, Keith E. Murphy   +2 more
core   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

TAM pathway proteins as novel salivary biomarkers for periodontitis

Journal of Periodontology, EarlyView.
Abstract Background The identification of molecular biomarkers that help clinicians in early diagnosis is a key focus of periodontal research. The major aim of this cross‐sectional observational study was to assess whether salivary TAM pathway protein levels have the potential to discriminate between periodontally healthy or gingivitis controls and ...
Karina Mendes, Ana T. P. C. Gomes, Dimitris N. Tatakis, Tiago Marques, Marla Pinto, Pedro C. Lopes, Maria J. Correia, Nuno Rosa   +7 more
wiley   +1 more source

Significant kidney impairment in pediatric inflammatory bowel disease and practice points for pediatric gastroenterologists

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Children with inflammatory bowel disease (IBD) have an increased risk of developing kidney disorders, which may cause significant kidney function impairment (SKI) or lead to chronic kidney disease (CKD). In this study we aimed to provide insights in causes and diagnoses of SKI cases and to provide recommendations for pediatric ...
Stephanie A. Vuijk, Renz C. W. Klomberg, Tobias Schwerd, Anne M. Griffiths, Séamus Hussey, Matthew W. Carroll, Petter Malmborg, Protima Deb, Margreet Wessels, Natalia Mouratidou, Stephanie van Biervliet, Michael Friedt, Susie Minson, Femke H. M. Vrieling‐Prince, Nicholas M. Croft, Lissy de Ridder, the PIBD‐SETQuality Safety Registry collaborative group   +16 more
wiley   +1 more source