Results 121 to 130 of about 8,337 (255)

Renal tubular lysozyme in tubulointerstitial diseases and renal sarcoidosis. [PDF]

Sarcoidosis Vasc Diffuse Lung Dis
Sanada S, Sato M.
europepmc   +1 more source

Real‐world efficacy and toxicity of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma according to IMDC risk criteria—A multi‐center retrospective analysis on behalf of the GUARDIANS group

International Journal of Cancer, Volume 158, Issue 9, Page 2440-2451, 1 May 2026.
What's new? The combination of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma has demonstrated durable response and tolerability in clinical trials. However, inclusion criteria for clinical studies are restrictive, and patients in the real‐world setting tend to have more comorbidities.
Hendrik Dinkel, Linus Materna, Ramona Stelmach, Stefanie Zschäbitz, Stephanie Neuberger, Can D. Aydogdu, Jozefina Casuscelli, Timo Egenolf, Matteo Silberg, Julie Steinestel, Arne Strauss, Florian Kirchhoff, Marit Ahrens, Pia Paffenholz, Richard Cathomas, Berna C. Özdemir, Christopher Gossler, Philipp Ivanyi, Marc Rehlinghaus, Thomas Hilser, Viktor Grünwald, Katrin Schlack   +21 more
wiley   +1 more source

Regional variation of underlying kidney diseases in children undergoing chronic kidney replacement therapy around the globe. [PDF]

Pediatr Nephrol
Borzych-Dużałka D, Bonthuis M, Ali U, Yap YC, Manno M, Zhai Y, Loza R, Hashmi S, Choi N, Soulami K, Exantus J, Al Riyami MS, Mabrouk S, Angeles MM, Zelaya-Camacho C, Puspitasari HA, Huque SS, Cano F, Ng KH, Bakkaloğlu SA, Harambat J, Jager KJ, Warady BA, Schaefer F.   +23 more
europepmc   +1 more source

Protective Effect of LGG From Lophatherum Gracile Brongn. on Alcohol‐Injured HepG2 Cells and Exploration of Potential Mechanism

eFood, Volume 7, Issue 2, April 2026.
LGG was separated from L. gracile and its hepatoprotective effect was investigated. LGG significantly reduced the mortality, ROS and MDA content in alcohol‐injured liver cells. LGG up‐regulated 156 mRNAs (63 miRNAs) and down‐regulated 1529 mRNAs (35 miRNAs).
Yi‐Long Ma, Xin Guo, Zheng‐Fang Wu, Qian‐Lan Wu, Jing Li, Tian‐Le Mao, Zhi Li, Ya‐Fang Shang, Kiran Thakur, Zhao‐Jun Wei   +9 more
wiley   +1 more source

miRNAs in Glomerular Diseases: From Pathogenic Insight to Therapeutic Potential: A Narrative Review. [PDF]

Cells
Apetrii M, Costache AD, Costache Enache II, Voroneanu L, Covic AS, Kanbay M, Scripcariu DV, Covic A.   +7 more
europepmc   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Corrigendum to "Pregnancies in Women With Kidney Failure on Home Dialysis in the United States" [<i>Kidney International Reports</i> Volume 9, Issue 4, April 2024, Pages 907-918]. [PDF]

Kidney Int Rep
Shah S, Weinhandl E, Leonard AC, Rachwal B, Verma P, Perl J, Christianson AL.   +6 more
europepmc   +1 more source

Tryptophan‐Derived Microbial Metabolite Indole‐3‐Acetic Acid Ameliorates Periodontitis Through AhR/CYP1A1‐Mediated Macrophage Polarisation

Journal of Clinical Periodontology, Volume 53, Issue 4, Page 644-655, April 2026.
ABSTRACT Aim To investigate the association between tryptophan‐derived microbial metabolites and periodontitis, and to assess whether the differential tryptophan metabolite indole‐3‐acetic acid (IAA) could ameliorate periodontitis and elucidate its potential mechanism.
Shuyu Cheng, Shiyuan Song, Wen Zhang, Dan Qiao, Min Wang, Zhifeng Wang, Jiajie Pu, Wenrong Yang, Fuhua Yan, Yangheng Zhang   +9 more
wiley   +1 more source

The immunomodulatory potential of bradykinin signaling in autoimmune conditions. [PDF]

Front Immunol
Szaryńska M, Olejniczak-Kęder A.
europepmc   +1 more source

Sharing Is Caring?—Pathogens and Pathogen‐Specific Antibodies in Arctic Endemic Seal Species and the Newly Sympatric Harbor Seals in Kongsfjorden, Svalbard

Marine Mammal Science, Volume 42, Issue 2, April 2026.
ABSTRACT Climate change associated transformations of Arctic marine ecosystems are having detrimental impacts on Arctic endemic marine mammals. However, warming conditions are providing new habitats for temperate marine mammals, some of which are expanding into Arctic regions, posing a threat of novel pathogen introduction and disease transmission.
Luca A. Schick, Kit M. Kovacs, Christian Lydersen, Simon Rohner, Ellen Prenger‐Berninghoff, Carsten Heydel, Christa Ewers, Alexander Postel, Nele Gremmel, Paul Becher, Christina Strube, Ursula Siebert   +11 more
wiley   +1 more source