A lupus nephritis kezelésének irányelvei, valamint a mycofenolat mofetil hatékonyságának bemutatása intézetünk lupus nephritises betegeinek körében | Clinical guideline for the treatment of lupus nephritis and single-centre results of mycofenolate mofetil among patients with lupus nephritis in the National Institute of Rheumatology and Physiotherapy, Budapest [PDF]
, 2016 Absztrakt A szerzők közleményükben a lupus nephritis kezelésének legújabb irányelvei mellett bemutatják saját mycofenolat mofetillel szerzett tapasztalataikat a betegség kezelésében.
Kiss, Emese, Szabó, Melinda Zsuzsanna
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Laboratuvar Hayvanlarında Deneysel Nefrotoksisite Modelleri
Laboratuvar Hayvanları Bilimi ve Uygulamaları DergisiHastalıkların mekanizmalarını daha iyi anlamak ve etkili tedavi yöntemleri geliştirebilmek amacıyla in vivo ve in vitro modellerin kullanımı, modern tıbbın ve biyomedikal araştırmaların temel taşlarından biri olarak kabul edilmektedir.
Abdurrahman Aksoy +1 more
doaj +1 more source
IL-34-Dependent Intrarenal and Systemic Mechanisms Promote Lupus Nephritis in MRL-Faslpr Mice.
Journal of the American Society of Nephrology, 2019 BACKGROUND In people with SLE and in the MRL-Faslpr lupus mouse model, macrophages and autoantibodies are central to lupus nephritis. IL-34 mediates macrophage survival and proliferation, is expressed by tubular epithelial cells (TECs), and binds to the ...
Y. Wada +6 more
semanticscholar +1 more source
A new prediction diagnosis model of incomplete Kawasaki disease based on data mining with big data
Pediatric Discovery, EarlyView.In this study, based on a medical big data information mining approach, we mined the independent risk factors for incomplete Kawasaki disease prediction by comparing incomplete Kawasaki disease with related febrile illnesses and constructed an auxiliary diagnostic model used to predict incomplete Kawasaki disease.
Zhen Yang +4 more
wiley +1 more source
Toll-like receptors in lupus nephritis
Journal of Biomedical Sciences, 2018 The pathogenesis of systemic autoimmune diseases such as systemic lupus erythematosus (SLE) is based on the loss of self-tolerance against ubiquitous autoantigens involving all mechanisms of adaptive immunity.
S. K. Devarapu, H. Anders
semanticscholar +1 more source
An Integrative Mechanistic Model of Type 1 IFN‐Mediated Inflammation in Systemic Lupus Erythematosus
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Type I interferon (IFN1) pathway–targeting therapies represent a highly promising class of remedies for the treatment of systemic lupus erythematosus. However, the overall clinical benefit of these compounds is afflicted by marked variability.
Alina Volkova +7 more
wiley +1 more source
Iguratimod alleviated Sjögren's syndrome through regulating macrophage polarization
Rheumatology &Autoimmunity, EarlyView.Nonobese diabetic (NOD) mice exhibited characteristic of Sjögren's syndrome (SS), with increased M1 macrophages and deceased M2 macrophages. Iguratimod alleviated SS‐like symptoms and restored balance of macrophage polarization through inhibiting the mitogen‐activated protein kinases pathway in NOD mice.
Junqiao Guo +7 more
wiley +1 more source
Rheumatology &Autoimmunity, EarlyView.OAS1 is an interferon‐induced gene that has been reported to be associated with the susceptibility of some infectious diseases, but there is little data on OAS1 single nucleotide polymorphism (SNP) associated with Systemic lupus erythematosus (SLE).
Xin Huang +4 more
wiley +1 more source
A Systematic Review and Meta-analysis of Prevalence of Biopsy-Proven Lupus Nephritis.
Archives of Rheumatology, 2018 Objectives This study aims to conduct a meta-analysis to clarify the epidemiologic characteristics of biopsy-proven lupus nephritis (BPLN), including those relating to its prevalence and prognosis.
Hong Wang +4 more
semanticscholar +1 more source