Results 21 to 30 of about 224,992 (367)
What is new in the management of rapidly progressive glomerulonephritis? [PDF]
, 2015 Rapidly progressive glomerulonephritis (RPGN) results from severe crescentic damage to glomeruli and leads to irreversible kidney failure if not diagnosed and managed in a timely fashion.
Greenhall, GHB, Salama, AD
core +1 more source
Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]
, 2000 The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim +1 more
core +1 more source
Revista Brasileira de Reumatologia, 2009 OBJETIVOS: Determinar a frequência de remissão total e parcial no tratamento da nefrite lúpica aos 12 e 24 meses de seguimento. Comparar esses subgrupos aos 12 meses, correlacionando as variáveis renais iniciais com a resposta ao tratamento.
Ana Karla Guedes de Melo +3 more
doaj +1 more source
Pharmaceutical Biology, 2022 Context Yi Shen An (YSA) is an investigational composite of traditional Chinese medicine (Reference: 2010L000974) for the treatment of renal disease.
Yun-Li Zhao +5 more
doaj +1 more source
American Society of Nephrology. Clinical Journal, 2017 SLE is a chronic inflammatory disease that affects the kidneys in about 50% of patients. Lupus nephritis is a major risk factor for overall morbidity and mortality in SLE, and despite potent anti-inflammatory and immunosuppressive therapies still ends in
S. Almaani, A. Meara, B. Rovin
semanticscholar +1 more source
Individualized decision aid for diverse women with lupus nephritis (IDEA-WON): A randomized controlled trial. [PDF]
, 2019 BackgroundTreatment decision-making regarding immunosuppressive therapy is challenging for individuals with lupus. We assessed the effectiveness of a decision aid for immunosuppressive therapy in lupus nephritis.Methods and findingsIn a United States ...
Alarcón, Graciela S +27 more
core +2 more sources
Clinical spectrum of systemic lupus erythematosus in children. Case report.
Revista de la Facultad de Medicina Humana, 2021 Systemic lupus erythematosus is an autoimmune disease with multisystem involvement, an alternating clinical course, and which constitutes a diagnostic challenge, with a greater disease activity in the pediatric age group, which also darkens its prognosis.
Giuliana Reyes-Florián +3 more
doaj +1 more source
Urinary Soluble CD163: a Novel Noninvasive Biomarker of Activity for Lupus Nephritis.
Journal of the American Society of Nephrology, 2020 BACKGROUND Clinical distinction between patients with lupus nephritis who have active inflammation or chronic kidney damage is challenging. Studies have shown soluble CD163, which derives from cleavage of the CD163 M2c macrophage receptor and can be ...
J. Mejía-Vilet +7 more
semanticscholar +1 more source
Origin of Proteinuria as Observed from Qualitative and Quantitative Analysis of Serum and Urinary Proteins [PDF]
Childhood Kidney Diseases, 2015 It is well known that proteins present in the primary urine are reabsorbed in the renal proximal tubules, and that this reabsorption is mediated via the megalin‐cubilin complex and the neonatal Fcγ receptor.
Shori Takahashi
doaj +1 more source
Nature Immunology, 2019 The molecular and cellular processes that lead to renal damage and to the heterogeneity of lupus nephritis (LN) are not well understood. We applied single-cell RNA sequencing (scRNA-seq) to renal biopsies from patients with LN and evaluated skin biopsies
E. Der +25 more
semanticscholar +1 more source