Results 31 to 40 of about 113,275 (214)

A proteinuria cut-off level of 0.7 g/day after 12 months of treatment best predicts long-term renal outcome in lupus nephritis: data from the MAINTAIN Nephritis Trial. [PDF]

, 2015
BACKGROUND: Although an early decrease in proteinuria has been correlated with good long-term renal outcome in lupus nephritis (LN), studies aimed at defining a cut-off proteinuria value are missing, except a recent analysis performed on patients ...
Tamirou, Farah, Rovin, Brad, Lauwerys, Bernard R., MAINTAIN Nephritis Trial, Houssiau, Frédéric, Dall'Era, Maria, MAINTAIN Nephritis Trial Investigators., Houssiau, Frédéric A., Lauwerys, Bernard, Mackay, Meggan, Cervera, Ricard   +10 more
core   +1 more source

Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis [PDF]

, 2010
Production of anti-dsDNA antibodies is a hallmark of lupus nephritis, but how these antibodies deposit in organs and elicit inflammatory damage remains unknown.
Chan, TM, Kwok Fan Cheung, Zhang, Q, Yung, S, Cheung, KF, Susan Yung, Qing Zhang, Tak Mao Chan   +7 more
core   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source

Vedolizumab-Induced Acute Interstitial Nephritis in Ulcerative Colitis [PDF]

, 2022
Vedolizumab is used in the treatment of inflammatory bowel disease and is generally well tolerated. We report a 20-year-old man who presented with right flank pain on a background of ulcerative colitis.
Sewwandi Francisco, Naveed Ishaq, Deloshaan Subhaharan, Ramaswamy, Pradeep K, Subhaharan, Deloshaan, Francisco, Sewwandi, Ramaswamy, Pradeep K., Ishaq, Naveed, Pradeep K. Ramaswamy   +8 more
core   +1 more source

Inflammatory Signatures and Biomarkers: The Renal-Vesical Axis in Alzheimer Progression [PDF]

International Neurourology Journal
Alzheimer disease (AD) has long been viewed as a disorder confined to the central nervous system. Accumulating evidence, however, indicates that systemic inflammation and peripheral organ dysfunction are closely linked to disease progression.
Yebeen Kim, Jaewoon Jung, Asifiwe Clarisse Cirunduzi, Seonghyun Yoon, Seokyoung Bang, Seung-Hoon Yang   +5 more
doaj   +1 more source

Long-term follow-up of the MAINTAIN Nephritis Trial, comparing azathioprine and mycophenolate mofetil as maintenance therapy of lupus nephritis. [PDF]

, 2016
OBJECTIVE: To report the 10-year follow-up of the MAINTAIN Nephritis Trial comparing azathioprine (AZA) and mycophenolate mofetil (MMF) as maintenance therapy of proliferative lupus nephritis, and to test different definitions of early response as ...
Tamirou, Farah, Fiehn, Christoph, Houssiau, Frédéric A, Gilboe, Inge-Magrethe, Houssiau, Frederic A., Ayala Guttierez, Maria Del Mar, Tektonidou, Maria, Sangle, Shirish, le Guern, Véronique, Houssiau, Frédéric, Cervera, Ricard, Guillevin, Loïc, Remy, Philippe, Ravelingien, Isabelle, Depresseux, Geneviève, MAINTAIN Nephritis Trial Group, D'Cruz, David, Blockmans, Daniel Engelbert, Vasconcelos, Carlos, Blockmans, Daniel   +19 more
core   +1 more source

Novel clinical and genetic insights into Gitelman syndrome from 95 Chinese patients

Human Genomics
Background Gitelman syndrome (GS) is a rare tubulopathy with clinical and genetic heterogeneity. This study aimed to investigate the characteristics of Chinese GS patients. Methods The diagnosis of GS was established by combining clinical phenotypes with
Xiaomeng Shi, Lu Zhang, Xing Chen, Peijin Bai, Leping Shao   +4 more
doaj   +1 more source

THE CLASSIFICATION OF NEPHRITIS [PDF]

Archives of Internal Medicine, 1913
Classifications of the so-called hematogenous inflammations of the kidney, commonly grouped as Bright's disease, have been made from five standpoints: 1. Etiological; 2, pathogenetic or histogenetic; 3, functional or physiological; 4, clinical (according to the symptom complex); 5, descriptive (a) according to the topography or (b) according to the ...
openaire   +2 more sources

Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]

, 2011
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto, Heni Eka Susanti, Adriana Migliorini, A. Migliorini, Susanti, Heni Eka, Hans-Joachim Anders, Christoph Römmele, Kulkarni, Onkar P., M. Lech, Cecilia Garlanda, Kulkarni Onkar P., Lech, Maciej, Lech Maciej, Garlanda Cecilia, C. Garlanda, Römmele, Christoph, Migliorini Adriana, Mantovani, Alberto, Alberto Mantovani, Anders Hans-Joachim, Onkar P Kulkarni, Maciej Lech, Susanti Heni Eka, A. Mantovani, Anders, Hans-Joachim, Römmele Christoph, H.E. Susanti, Migliorini, Adriana, O.P. Kulkarni, C. Römmele, H. J. Anders, Garlanda, Cecilia, Onkar P. Kulkarni   +32 more
core   +1 more source

Unveiling the immune landscape and microenvironmental architecture of IgA nephropathy using single‐cell imaging mass cytometry

Clinical & Translational Immunology
Objective The heterogeneity in the pathology of IgA nephropathy (IgAN) represents a significant gap in current research, emphasising the need for individualised treatment strategies.
Xing Chen, Long Liu, Lijing Yao, Jianxin Shen, Hengyuan Zhang, Leping Shao, Xingxing Yu, Zhijuan Lin, Lu Zhang   +8 more
doaj   +1 more source