Results 31 to 40 of about 158,092 (291)
Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus [PDF]
Introduction ES-62, a phosphorylcholine (PC)-containing immunomodulator secreted by the parasitic worm Acanthocheilonema viteae, protects against nephritis in the MRL/Lpr mouse model of systemic lupus erythematosus (SLE).
Harnett, M. M. +4 more
core +1 more source
SummaryInterstitial nephritis is an inflammatory process within the renal interstitium, and was one of the first observations made in the description of renal histopathology. Many different conditions are associated with an interstitial nephritis, and as a clinical diagnosis the term has little use unless causation is defined.
S, Dhillon, R M, Higgins
openaire +2 more sources
Immunoglobulin a vasculitis after a not so innocuous wasp bite
Background: Immunoglobulin A vasculitis (IgAV), previously known as Henoch–Schonlein purpura (HSP), is the most common vasculitis in children. Previous studies have identified various triggers of IgAV, with infections being the most common.
Aditi Sharma +2 more
doaj +1 more source
Anti-CTLA-4 (CD 152) monoclonal antibody-induced autoimmune interstitial nephritis [PDF]
Targeted immune-modulating agents are entering clinical practice in many specialties, providing novel therapeutic possibilities but introducing new potential toxicities.
Clatworthy, Menna R +4 more
core +2 more sources
Contains fulltext : 24337___.PDF (Publisher’s version ) (Open Access)
openaire +3 more sources
Background and Aims There are limited studies on the epidemiology of chronic kidney disease (CKD) burden among adolescents and emerging adults. We aimed to assess the global, regional, and national trends in CKD burden among adolescents and emerging ...
Zhi Wang +4 more
doaj +1 more source
Proton pump inhibitors are associated with increased risk of development of chronic kidney disease [PDF]
Background Acute interstitial nephritis secondary to proton pump inhibitors (PPIs) frequently goes undiagnosed due to its subacute clinical presentation, which may later present as chronic kidney disease (CKD).
Arora, Pradeep +6 more
core +2 more sources
B cells in SLE. Different biological drugs for different pathogenic mechanisms [PDF]
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by a complex multi-factorial pathogenesis and a great clinical polymorphism. SLE is considered to be a B cell disease in which autoantibodies are the major players. Recently,
Carsetti, Rita +3 more
core +1 more source
Novel clinical and genetic insights into Gitelman syndrome from 95 Chinese patients
Background Gitelman syndrome (GS) is a rare tubulopathy with clinical and genetic heterogeneity. This study aimed to investigate the characteristics of Chinese GS patients. Methods The diagnosis of GS was established by combining clinical phenotypes with
Xiaomeng Shi +4 more
doaj +1 more source
Inflammatory Signatures and Biomarkers: The Renal-Vesical Axis in Alzheimer Progression [PDF]
Alzheimer disease (AD) has long been viewed as a disorder confined to the central nervous system. Accumulating evidence, however, indicates that systemic inflammation and peripheral organ dysfunction are closely linked to disease progression.
Yebeen Kim +5 more
doaj +1 more source

