Results 51 to 60 of about 158,092 (291)
Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome [PDF]
Objective: Previous studies have shown the importance of somatic mutations and arginine residues in the complementarity-determining regions (CDRs) of pathogenic anti-double-stranded DNA (anti-dsDNA) antibodies in human and murine lupus, and in studies of
Giles, I. +7 more
core +1 more source
Rheumatologic Manifestations of Patients With Type B Insulin Resistance
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya +4 more
wiley +1 more source
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh +5 more
wiley +1 more source
Laboratuvar Hayvanlarında Deneysel Nefrotoksisite Modelleri
Hastalıkların mekanizmalarını daha iyi anlamak ve etkili tedavi yöntemleri geliştirebilmek amacıyla in vivo ve in vitro modellerin kullanımı, modern tıbbın ve biyomedikal araştırmaların temel taşlarından biri olarak kabul edilmektedir.
Abdurrahman Aksoy +1 more
doaj +1 more source
PROBLEM OF DIAGNOSIS OF EARLY CONGENITAL SYPHILIS
The paper presents a case of delayed diagnosis of early congenital syphilis in a child whose mother was observed in prenatal clinic starting from the 14th week of pregnancy. The child had specific skin rash already in maternity.
G. P. Martynova, N. F. Kuznetsova
doaj +1 more source
Mercury exposure mimicking systemic lupus erythematosus in a thirteen-year-old girl
Background. The clinical presentation of mercury (Hg) intoxication may mimic rheumatic diseases. Hg exposure is associated with systemic lupus erythematosus (SLE)-like disease in genetically susceptible rodents and Hg is among the environmental ...
Hakan Kısaoğlu +2 more
doaj +1 more source
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns +2 more
wiley +1 more source
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah +13 more
wiley +1 more source
A Case Report of Infective Endocarditic Induced Acute Renal Failure
Introduction: Prevalence of infective endocarditic induced renal failure is 1-3% and is one of the causes of deterioration of patient or cessation of antibiotic therapy and also delay in treatment duration and medical response.
Shahram Homayonfar +2 more
doaj

