Results 61 to 70 of about 112,843 (300)

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

A rare and important case of Staphylococcus haemolyticus‐associated ventricular atrial shunt nephritis

Clinical Case Reports, 2017
Key Clinical Message Shunt nephritis is a rare and relatively new diagnosis involving glomerular kidney damage following ventriculoperitoneal and ventriculoatrial shunt placement.
Kyle Suen, Ardavan Mashhadian, Ian Figarsky, Jeff Payumo, Antonio Liu   +4 more
doaj   +1 more source

Serum cytokine profile in patients with active lupus nephritis

, 2012
Determination of disease activity of lupus nephritis remains challenging. Since cytokines play a role as inflammatory mediators extending renal injury, measuring serum cytokine levels might help in the clinical assessment of patients with lupus nephritis.
Eisenberger, U., Koenig, Katrin Franzika, Groeschl, Isabel, Tesar, Vladimir, Koenig, K. F., Trendelenburg, Marten, Tesar, V., Pesickova, Satu Sinikka, Eisenberger, Ute, Groeschl, I., Pesickova, S. S., Trendelenburg, M.   +11 more
core   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Shunt nephritis [PDF]

, 2014
Shunt nephritis is a rare complication associated with the use of atrialventricular shunts and their chronic infection. The microorganisms that cause the infection are generally of low virulence, but they can produce long term infections that permit the ...
Parra, Viviana, Gualteros, Sandra, Sandra Gualteros, Sandra Gualtero T, Viviana Parra, Patricia Medina, Patricia Medina A, Viviana Parra I, Medina, Patricia, Valderrama, Sandra, Sandra Valderrama   +10 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Nephronophthisis and medullary cystic kidney disease complex [PDF]

Vojnosanitetski Pregled, 2005
Background. Nephronophthisis and medullary cystic kidney disease complex refers to the genetic heterogeneous group of inherited tubulointerstital nephritis. Nephronophthisis comprises at last 3 clinical manifestations, has the autosomal recessive pattern
Stanišić Marijana, Hrvačević Rajko, Paunić Zoran, Petrović Stanko   +3 more
doaj   +1 more source

Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis

, 2010
Production of anti-dsDNA antibodies is a hallmark of lupus nephritis, but how these antibodies deposit in organs and elicit inflammatory damage remains unknown.
Chan, TM, Kwok Fan Cheung, Zhang, Q, Yung, S, Cheung, KF, Susan Yung, Qing Zhang, Tak Mao Chan   +7 more
core   +1 more source

Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models

Advanced Science, EarlyView.
Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler, Tim Lange, Sophia‐Marie Bach, Soeren S. Lienkamp, Nicole Endlich   +4 more
wiley   +1 more source

Vedolizumab-Induced Acute Interstitial Nephritis in Ulcerative Colitis

, 2022
Vedolizumab is used in the treatment of inflammatory bowel disease and is generally well tolerated. We report a 20-year-old man who presented with right flank pain on a background of ulcerative colitis.
Sewwandi Francisco, Naveed Ishaq, Deloshaan Subhaharan, Ramaswamy, Pradeep K, Subhaharan, Deloshaan, Francisco, Sewwandi, Ramaswamy, Pradeep K., Ishaq, Naveed, Pradeep K. Ramaswamy   +8 more
core   +1 more source