Results 21 to 30 of about 112,843 (300)

Treatment of active lupus nephritis with the novel immunosuppressant 15-deoxyspergualin : an open-label dose escalation study [PDF]

, 2011
Introduction: As the immunosuppressive potency of 15-deoxyspergualin (DSG) has been shown in the therapy of renal transplant rejection and Wegener's granulomatosis, the intention of this study was to evaluate the safety of DSG in the therapy of lupus ...
Hauser, Ingeborg A., Tesar, Vladimir, Heinzel, Peter A., Hiepe, Falk, Peter A Heinzel, Wilhelm H Schmitt, Vladimir Tesar, Ulf Müller-Ladner, Woehling, Heike, Nemoto, Kyuichi, Heike Woehling, Hanns-Martin Lorenz, Müller-Ladner, Ulf, Kyuichi Nemoto, Falk Hiepe, Lorenz, Hanns-Martin, Tarner, Ingo, Ingo Tarner, Tobias Alexander, Schmitt, Wilhelm H., Ingeborg A Hauser, Alexander, Tobias   +21 more
core   +1 more source

Autoantibodies against complement C1q in systemic lupus erythemathosus [PDF]

, 2008
Complement and C1q, the first component of the classical pathway of activation of the complement system, are considered to be involved in the pathogenesis of systemic lupus erythematosus (SLE), a systemic autoimmune disease.
Bigler, Cornelia
core   +1 more source

Lupus nephritis

Kidney International, 1997
Contains fulltext : 24337___.PDF (Publisher’s version ) (Open Access)
openaire   +3 more sources

A proteinuria cut-off level of 0.7 g/day after 12 months of treatment best predicts long-term renal outcome in lupus nephritis: data from the MAINTAIN Nephritis Trial. [PDF]

, 2015
BACKGROUND: Although an early decrease in proteinuria has been correlated with good long-term renal outcome in lupus nephritis (LN), studies aimed at defining a cut-off proteinuria value are missing, except a recent analysis performed on patients ...
Tamirou, Farah, Rovin, Brad, Lauwerys, Bernard R., MAINTAIN Nephritis Trial, Houssiau, Frédéric, Dall'Era, Maria, MAINTAIN Nephritis Trial Investigators., Houssiau, Frédéric A., Lauwerys, Bernard, Mackay, Meggan, Cervera, Ricard   +10 more
core   +1 more source

Lupus Nephritis: Current Perspectives and Moving Forward

, 2022
Julia Lichtnekert, Hans-Joachim Anders, Maciej Lech Nephrologisches Zentrum, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, München, GermanyCorrespondence: Maciej Lech, Medizinische Klinik und Poliklinik IV Klinikum
Lichtnekert J, Lech M, Anders HJ
core  

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source

Inflammatory Signatures and Biomarkers: The Renal-Vesical Axis in Alzheimer Progression [PDF]

International Neurourology Journal
Alzheimer disease (AD) has long been viewed as a disorder confined to the central nervous system. Accumulating evidence, however, indicates that systemic inflammation and peripheral organ dysfunction are closely linked to disease progression.
Yebeen Kim, Jaewoon Jung, Asifiwe Clarisse Cirunduzi, Seonghyun Yoon, Seokyoung Bang, Seung-Hoon Yang   +5 more
doaj   +1 more source

Long-term follow-up of the MAINTAIN Nephritis Trial, comparing azathioprine and mycophenolate mofetil as maintenance therapy of lupus nephritis. [PDF]

, 2016
OBJECTIVE: To report the 10-year follow-up of the MAINTAIN Nephritis Trial comparing azathioprine (AZA) and mycophenolate mofetil (MMF) as maintenance therapy of proliferative lupus nephritis, and to test different definitions of early response as ...
Tamirou, Farah, Fiehn, Christoph, Houssiau, Frédéric A, Gilboe, Inge-Magrethe, Houssiau, Frederic A., Ayala Guttierez, Maria Del Mar, Tektonidou, Maria, Sangle, Shirish, le Guern, Véronique, Houssiau, Frédéric, Cervera, Ricard, Guillevin, Loïc, Remy, Philippe, Ravelingien, Isabelle, Depresseux, Geneviève, MAINTAIN Nephritis Trial Group, D'Cruz, David, Blockmans, Daniel Engelbert, Vasconcelos, Carlos, Blockmans, Daniel   +19 more
core   +1 more source

Novel clinical and genetic insights into Gitelman syndrome from 95 Chinese patients

Human Genomics
Background Gitelman syndrome (GS) is a rare tubulopathy with clinical and genetic heterogeneity. This study aimed to investigate the characteristics of Chinese GS patients. Methods The diagnosis of GS was established by combining clinical phenotypes with
Xiaomeng Shi, Lu Zhang, Xing Chen, Peijin Bai, Leping Shao   +4 more
doaj   +1 more source

Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]

, 2011
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto, Heni Eka Susanti, Adriana Migliorini, A. Migliorini, Susanti, Heni Eka, Hans-Joachim Anders, Christoph Römmele, Kulkarni, Onkar P., M. Lech, Cecilia Garlanda, Kulkarni Onkar P., Lech, Maciej, Lech Maciej, Garlanda Cecilia, C. Garlanda, Römmele, Christoph, Migliorini Adriana, Mantovani, Alberto, Alberto Mantovani, Anders Hans-Joachim, Onkar P Kulkarni, Maciej Lech, Susanti Heni Eka, A. Mantovani, Anders, Hans-Joachim, Römmele Christoph, H.E. Susanti, Migliorini, Adriana, O.P. Kulkarni, C. Römmele, H. J. Anders, Garlanda, Cecilia, Onkar P. Kulkarni   +32 more
core   +1 more source