Results 81 to 90 of about 173,599 (327)

Mesangial cell: A hub in lupus nephritis [PDF]

, 2022
Mengdi Liu, Lei Zhang, Yixin Wang, Weijie Hu, Chunhong Wang, Zhenke Wen   +5 more
openalex   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Efficacy of Telitacicept in Childhood‐Onset Systemic Lupus Erythematosus: A Prospective Multicenter Cohort Study With Inverse Probability of Treatment Weighting –Adjusted Comparison to a Historical Control Group Treated With Belimumab

Arthritis &Rheumatology, EarlyView.
Objective The therapeutic effects of telitacicept combined with standard of care (SoC) in childhood‐onset systemic lupus erythematosus (cSLE) remain unclear. This study aims to evaluate its efficacy in comparison with belimumab combined with SoC.
Chong Luo, Shu Su, Jingyue Liu, Junyu Lin, Jin Song, Zongwen Chen, Yuanyuan Peng, Lijun Jiang, Meng Jia, Li Wang, Xinhui Jiang, Wei Zhang, Zanhua Rong, Bo Zhao, Yajun Wang, Xuemei Tang   +15 more
wiley   +1 more source

Continuous Exposure to Environmental Endocrine Disruptors on the Prognosis of Children With Nephritis: An Observational Cohort Study

Reproductive, Female and Child Health
Objective Explore the impact of partial urinary environmental endocrine disruptors (EEDs) on the pathogenesis and renal function in paediatric patients diagnosed with Henoch‐Schönlein purpura nephritis (HSPN).
Hongjun Peng, Shuting Yu, Yaning Zheng, Taiyu Song, Jinya Wang, Xianguo Ren, Guangling Liu   +6 more
doaj   +1 more source

Accelerated Atherosclerosis in Systemic Lupus Erythematosus: Role of Fibroblast Growth Factor 23- Phosphate Axis

International Journal of Nephrology and Renovascular Disease, 2021
Yaser Ammar,1 Amira Mohamed,1 Gihane Khalil,2 Dalia Maharem1 1Internal Medicine Department, Medical Research Institute, Alexandria University, Alexandria, Egypt; 2Chemical Pathology Department, Medical Research Institute, Alexandria University ...
Ammar Y, Mohamed A, Khalil G, Maharem D
doaj  

Collapsing glomerulopathy in a patient with APOL1 intermediate-risk genotype triggered by lupus nephritis and SARS-CoV-2 infection: lessons for the clinical nephrologist [PDF]

, 2021
Christophe Masset, Karine Renaudin, Delphine Kervella, Agnès Chapelet, Clément Deltombe, Simon Ville   +5 more
openalex   +1 more source

Peripheral Blood B Cell Depletion after Rituximab and Complete Response in Lupus Nephritis.

American Society of Nephrology. Clinical Journal, 2018
BACKGROUND AND OBJECTIVES Incomplete peripheral blood B cell depletion after rituximab in lupus nephritis might correlate with inability to reduce tubulointerstitial lymphoid aggregates in the kidney, which together could be responsible for inadequate ...
L. M. Gomez Mendez, M. Cascino, J. Garg, T. Katsumoto, P. Brakeman, M. Dall'era, R. Looney, B. Rovin, L. Dragone, P. Brunetta   +9 more
semanticscholar   +1 more source

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify noninvasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin, Leonardo Palazzo, Agnes B. Fogo, Mark Haas, David R. W. Jayne, Liz Lightstone, Brad H. Rovin, Surya V. Seshan, Augusto Vaglio, Ioannis Parodis, Ingeborg M. Bajema, for the Lupus Nephritis Classification Steering Committee   +11 more
wiley   +1 more source

Sensitivity and Specificity of Pathologic Findings to Diagnose Lupus Nephritis.

American Society of Nephrology. Clinical Journal, 2019
BACKGROUND AND OBJECTIVES In 2012, the Systemic Lupus International Collaborating Clinics proposed that lupus nephritis, in the presence of positive ANA or anti-dsDNA antibody, is sufficient to diagnose SLE.
Satoru Kudose, D. Santoriello, A. Bomback, M. Stokes, V. D’Agati, G. Markowitz   +5 more
semanticscholar   +1 more source

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source