Results 11 to 20 of about 14,084 (155)

Integrative Genomic Profiling of Pediatric Solid Tumors Reveals Clinically Relevant Variants and Chromosomal Arm Aneuploidies Signatures. [PDF]

Cancer Med
ABSTRACT Background Pediatric malignancies have emerged as the leading cause of disease‐related mortality in children, exhibiting distinct etiological and molecular characteristics compared to adult cancers. Despite advances in genomic profiling, the molecular landscape of pediatric solid tumors, particularly in Chinese populations, remains ...
Yan B, Wang J, Xiong J, Liu S, Tang Y, He Z, Yan H, Guo B, Chen C, Zhang Y, Zhu Q, Cai J, He M, Wu X, Mao J, Zhang L, Gu W, Zhu Z, Li Z, Xiao R, Shu Q, Yu G, Tao T.   +22 more
europepmc   +2 more sources

Proton beam therapy in paediatric cancer: Anticipating the opening of the Australian Bragg Centre for Proton Therapy and Research

Journal of Medical Imaging and Radiation Oncology, EarlyView., 2023
Summary Proton Beam Therapy (PBT) has the potential to improve paediatric cancer care by reducing radiation exposure and thus long‐term toxicities. Ethical concerns and debates surrounding the treatment, such as eligibility and accessibility, are ongoing in Australia. The Australian Bragg Centre for Proton Therapy and Research (ABCPTR) (named after Sir
Jeremy Khong, Hui Tee, Peter Gorayski, Hien Le, Michael Penniment, Sophie Jessop, Jordan Hansford, Melanie Penfold, Julia Green, Kelly Skelton, Frank Saran   +10 more
wiley   +1 more source

Adult nephroblastoma [PDF]

Cancer, 1988
Clinical, pathologic, and ultrastructural features of two cases of adult nephroblastoma (Wilms' tumor) are presented, one in a 77-year-old man who had a large tumor with extracapsular extension and blood vessel invasion. Histologically, it consisted mainly of blastema.
M, Lurie, I, Sova, Y, Mecz, A, Lurie
openaire   +2 more sources

Cystic partially differentiated nephroblastoma-like lesion following neo-adjuvant chemotherapy for nephroblastoma: A case report and review of the literature

Human Pathology: Case Reports, 2020
Cystic partially differentiated nephroblastoma (CPDN) and cystic nephroblastoma are paediatric renal tumours characterised by the presence of a variable combination of primitive epithelium, immature stroma and blastema.
C. Bruce-Brand, M. Reyes-Múgica, A. van Zyl, P.T. Schubert   +3 more
doaj   +1 more source

Recurrent nephroblastoma in the bladder: Successful transurethral resection

Journal of Pediatric Surgery Case Reports, 2021
Nephroblastoma is the second most common intraabdominal cancer of childhood and the fifth most common pediatric malignancy. Most of the cases occur in children less than 5 years of age with a peak incidence at 2–3 years of age.
Siti Hafzan Abd Karim, Mohamed Ashraf Mohamed Daud, MBBS, MMed(Surgery),FRCS(Urol)(Glasg), FEBU, Ariffin Nasir, Norsarwany Mohamad   +3 more
doaj   +1 more source

High cyclin E staining index in blastemal, stromal or epithelial cells is correlated with tumor aggressiveness in patients with nephroblastoma. [PDF]

PLoS ONE, 2008
PURPOSE: Identifying among nephroblastoma those with a high propensity for distant metastases using cell cycle markers: cyclin E as a regulator of progression through the cell cycle and Ki-67 as a tumor proliferation marker, since both are often ...
Dominique Berrebi, Julie Leclerc, Gudrun Schleiermacher, Isabelle Zaccaria, Liliane Boccon-Gibod, Monique Fabre, Francis Jaubert, Alaa El Ghoneimi, Cécile Jeanpierre, Michel Peuchmaur   +9 more
doaj   +1 more source

S100A16 cooperates with DEPDC1 to promote the progression and angiogenesis of nephroblastoma through PI3K/Akt/mTOR pathway

Polish Journal of Pathology, 2023
S100 calcium-binding protein A16 (S100A16) has previously been reported to play a role in tumor cells. Nevertheless, the role that S100A16 played in nephroblastoma cells remains obscure.
Geng Geng, Yongtao Xu, Qingfang Li, Qinghao Li, Lili Yuan, Mengyao Dong, Ming Ming   +6 more
doaj   +1 more source

Duplex kidney complicated with preoperative inferior nephroblastoma rupture in children: a case report and literature review

BMC Pediatrics, 2021
Background We admitted a child with a duplex kidney combined with preoperative rupture of nephroblastoma and used this case to discuss the clinical features and treatment of this disease. Case presentation We retrospectively analyzed the clinical data of
Yongxiang Zhao, Haiyan Cheng, Hongcheng Song, Ruimin Zhang, Xiangming Wu, Haowei Li, Jun Wang, Huanmin Wang, Chunmei Jia   +8 more
doaj   +1 more source

BARD1 Gene Polymorphisms Confer Nephroblastoma Susceptibility

EBioMedicine, 2017
BRCA1-associated RING domain protein 1 (BARD1) is a tumor suppressor, which forms a heterodimer with BRCA1. Three BARD1 gene polymorphisms (rs7585356 G>A, rs6435862 T>G and rs3768716 A>G) were initially identified as high-risk neuroblastoma ...
Wen Fu, Jinhong Zhu, Si-Wei Xiong, Wei Jia, Zhang Zhao, Shi-Bo Zhu, Jin-Hua Hu, Feng-Hua Wang, Huimin Xia, Jing He, Guo-Chang Liu   +10 more
doaj   +1 more source

LINC01006 inhibits proliferation and invasion and promotes apoptosis of nephroblastoma cells by down-regulating miR-148a-3p to block MEOX2/PI3K/Akt pathway

Di-san junyi daxue xuebao, 2020
Objective To investigate the role of long noncoding RNA LINC01006 in regulating the proliferation, invasion and apoptosis of nephroblastoma cells and explore the molecular mechanism.
ZHAO Ting, LIU Ansheng, WANG Hua, FU Qiang   +3 more
doaj   +1 more source