Results 41 to 50 of about 15,593 (210)

Persistent Erythrocytosis in a Dog With a Spinal Sclerosing Paraganglioma

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT A 7‐year‐old, male, castrated, mixed‐breed dog presented with right pelvic limb lameness and pain on posturing to defecate that began 1.5 years prior to presentation. Radiographs taken 8 months prior to presentation showed a small lytic lesion of the L6 vertebral body, and CBCs showed a persistently increased hematocrit (HCT) for at least 2 ...
Samuel V. Neal   +11 more
wiley   +1 more source

Case report: Severe, refractory hypoglycemia in a 9-year-old Brittany Spaniel with renal nephroblastoma

open access: yesFrontiers in Veterinary Science, 2023
A 9-year-old female spayed Brittany Spaniel presented for weakness and stumbling, and was diagnosed with severe hypoglycemia. An insulin to glucose ratio was not consistent with insulinoma as a cause for hypoglycemia.
Paula Simons   +6 more
doaj   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

open access: yesPediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter   +17 more
wiley   +1 more source

ZSTK474 targeting PIK3R3 inhibits the Wilms' tumor through G0 / G1 phase arrest.

open access: yesPLoS ONE
PurposeWilms' tumor (WT), also known as nephroblastoma, is the predominant form of primary malignant renal cancer. The unfavorable prognoses linked to anaplastic nephroblastoma and recurrent nephroblastoma emphasize the crucial requirement for the ...
Maoxian Li   +11 more
doaj   +1 more source

Proposal of a Risk Stratification Algorithm for Extracranial Malignant Rhabdoid Tumors

open access: yesCancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Malignant rhabdoid tumors (MRT) are highly aggressive tumors, primarily described in children, but also affecting adults. The objective was to identify independent prognostic factors to predict individual patients' risk and to establish an age‐spanning risk stratification system for prospective trials. Patients and Methods Data from
Juno Eberl   +2 more
wiley   +1 more source

Autophagy Inhibition in Childhood Nephroblastoma and the Therapeutic Significance

open access: yes, 2018
Background: Autophagy is a physiological pathway characterized by lysosomedependent self-digestion to recycle damaged or superfluous cellular content.
Yi-Long Wang   +11 more
core   +1 more source

Intrarenal Pelvic Nephroblastoma in a Meerkat (Suricata Suricatta)

open access: yes, 2005
Nephroblastoma is the most common primary renal tumor in children and has also been reported in domestic and nondomestic animal species. Intrapelvic renal nephroblastoma is a rare variant of this tumor type in human patients. Postmortem examination of a
Sharon P. Redrobe   +3 more
core   +1 more source

Alagille syndrome and nephroblastoma: Unusual coincidence of two rare disorders

open access: yes, 2008
Alagille syndrome is a rare developmental disorder combining bile duct paucity, congenital cardiopathy, facial dysmorphy, vertebrae defects, and ocular abnormalities; and frequent renal abnormalities.
PATTE, Catherine   +17 more
core   +1 more source

A working model for CCN3 C‐terminal domain‐mediated transcriptional modulation of the plasminogen activation system

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Plasminogen is a circulating zymogen that is converted into active plasmin by plasminogen activators such as tissue plasminogen activator (tPA) and urokinase‐type PA (uPA). This conversion is regulated by plasminogen activator inhibitors (PAI‐1, PAI‐2) and by inhibitors of plasmin itself, maintaining a fine balance between activation and inhibition of ...
Bernard Perbal
wiley   +1 more source

Renal nephroblastoma in a 17-month-old Jack Russell Terrier

open access: yes, 2019
A 17 mo old female Jack Russell terrier was diagnosed with unilateral primary malignant nephroblastoma. The dog presented with polyuria and polydipsia. Laboratory tests revealed polycythemia and elevated serum erythropoietin levels. Diagnostic imaging (i.
von Bomhard, Wolf   +4 more
core   +1 more source

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