Results 61 to 70 of about 16,522 (203)

Multi-Omics Integration Reveals a Competitive Endogenous RNAs Network for the Identification of Progression Biomarkers and the Stratification of Patients Diagnosed With Nephroblastoma

Frontiers in Oncology, 2020
Specific types of nephroblastoma (Wilms' tumor, WT) are known to associate with poor overall survival. Emerging experimental evidence has demonstrated that competitive endogenous RNA (ceRNA) networks have important roles in regulating cancer occurrence ...
Jingbo Wang, Jingbo Wang, Yuan Wang, Liang Han, Mohamed Shahen, Chaofeng Hu, Furong Li, Furong Li   +7 more
doaj   +1 more source

Multiple congenital anomalies in a neonatal goat kid: Atresia ani, rectovaginal fistula, renal fusion, ectopic ureter and sinus of Valsalva aneurysm

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 2‐week‐old female Anglo‐Nubian goat kid was presented with rectal malformation and signs of lower urinary and gastrointestinal dysfunction. Postmortem examination revealed multiple congenital anomalies including atresia ani with a rectovaginal fistula, right‐sided extramural ectopic ureter, renal fusion with unilateral severe pallor and ...
Caro Wilson, Sarah Linn‐Peirano, Amy Brandon, Meggan Graves   +3 more
wiley   +1 more source

miR-140-5p could suppress tumor proliferation and progression by targeting TGFBRI/SMAD2/3 and IGF-1R/AKT signaling pathways in Wilms’ tumor

BMC Cancer, 2019
Background Wilms’ tumor is also called nephroblastoma and is the most common pediatric renal cancer. Several genetic and epigenetic factors have been found to account for the development of Wilms’ tumor.
Zhuo Liu, Feng He, Shengrong OuYang, Yuanyuan Li, Feifei Ma, Huibo Chang, Dingding Cao, Jianxin Wu   +7 more
doaj   +1 more source

Cryptogenic Stroke and Valvular Strands

European Journal of Case Reports in Internal Medicine, 2020
Background: Ischaemic stroke can be classified according to its aetiology. In cryptogenic stroke, Lambl’s excrescences should be considered since they can only be detected through transesophageal echocardiography (TEE), which is not routinely performed ...
Cátia Castanheira Figueiredo, Carla Sofia Rebelo, Joana Lemos   +2 more
doaj   +1 more source

Defining Cachexia in Children With Cancer in the United States: Developing a Framework to Inform Clinical and Research Practice

Journal of Human Nutrition and Dietetics, Volume 39, Issue 4, August 2026.
ABSTRACT Background Cancer cachexia describes the muscle and weight loss, anorexia, and physical impairment common in certain adult cancers. No formal criteria exist to define paediatric cancer cachexia, making its clinical recognition and impact largely unknown. Using established undernutrition guidelines, criteria were developed to identify potential
Daniel V. Runco, Guohai Zhou, Adina R. Lemeshow, Stephen E. Schachterle, Agnieszka Gajewska, Ira Jacobs, Alexandra Palmer, Xunming Sun   +7 more
wiley   +1 more source

Rare cases of a second recurrence of nephroblastoma with MLLT1 gene mutation: case report and literature review

Frontiers in Oncology
Nephroblastoma or Wilms tumor is the most common tumor of the urinary system in childhood. The survival rate can reach more than 90% after multidisciplinary treatment, but there is still a certain recurrence rate.
Yiling Dai, Yiling Dai, Yiling Dai, Xin Chen, Xin Chen, Xin Chen, Xin Chen, Guoqian He, Guoqian He, Guoqian He, Ju Gao, Ju Gao, Ju Gao, Xia Guo, Xia Guo, Xia Guo, Xia Guo   +16 more
doaj   +1 more source

Significant haematuria caused by a pseudo-aneurysm in nephroblastoma

Journal of Pediatric Surgery Case Reports, 2019
A 7-year-old boy presented with a nephroblastoma, frank haematuria and hypovolemic shock. The haemorrhage was controlled with embolization of the right renal artery and followed by a nephrectomy.
Jaques van Heerden, Hansraj Mangray, Fernando Ghimenton, Deneys Reitz   +3 more
doaj   +1 more source

Implications of cell division cycle associated 4 on the Wilm’s tumor cells viability via AKT/mTOR signaling pathway

Renal Failure, 2021
Objective The aim of present report was to elucidate the effect of cell division cycle associated 4 (CDCA4) on the proliferation and apoptosis of Wilm’s tumor cells, and to further evaluate its underlying mechanism.
Suqing Li, Cong Qin, Yike Chen, Dan Wei, Zhijun Tan, Jiadong Meng   +5 more
doaj   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Proposal of a Risk Stratification Algorithm for Extracranial Malignant Rhabdoid Tumors

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Malignant rhabdoid tumors (MRT) are highly aggressive tumors, primarily described in children, but also affecting adults. The objective was to identify independent prognostic factors to predict individual patients' risk and to establish an age‐spanning risk stratification system for prospective trials. Patients and Methods Data from
Juno Eberl, Angelika Eggert, Monika Scheer   +2 more
wiley   +1 more source