Results 61 to 70 of about 15,593 (210)

Implications of cell division cycle associated 4 on the Wilm’s tumor cells viability via AKT/mTOR signaling pathway

Renal Failure, 2021
Objective The aim of present report was to elucidate the effect of cell division cycle associated 4 (CDCA4) on the proliferation and apoptosis of Wilm’s tumor cells, and to further evaluate its underlying mechanism.
Suqing Li, Cong Qin, Yike Chen, Dan Wei, Zhijun Tan, Jiadong Meng   +5 more
doaj   +1 more source

Deep Learning‐Based Analysis of Gene Expression Data and Gene‐Related Information in Pediatric Surgical Oncology: A Scoping Review

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Deep learning (DL) methods may enhance analysis of complex gene expression data to aid in diagnosis and treatment planning for pediatric extracranial tumors. However, the literature regarding the application of DL to gene expression data in this field remains limited. This scoping review was based on the question “What is the current status of
Simon Berhe, Steffen E. Fuchs, Altuna Akalin, Alida F. W. van der Steeg, Steven W. Warmann, Myrthe A. D. Buser, Moritz Markel   +6 more
wiley   +1 more source

Spinal cord nephroblastoma in dogs: 11 cases (1985–2007)

, 2011
Objective—To evaluate clinical features and outcome of dogs with a confirmed spinal cord nephroblastoma and to describe the use of Wilms tumor-1 (WT-1) immunohistochemical staining to confirm a diagnosis of nephroblastoma in dogs.
Sofia Cerda-Gonzalez, Anh N. Diep, David M. Brewer, Sean P. McDonough, Kristin Van Horne, Curtis W. Dewey   +5 more
core   +1 more source

miR-140-5p could suppress tumor proliferation and progression by targeting TGFBRI/SMAD2/3 and IGF-1R/AKT signaling pathways in Wilms’ tumor

BMC Cancer, 2019
Background Wilms’ tumor is also called nephroblastoma and is the most common pediatric renal cancer. Several genetic and epigenetic factors have been found to account for the development of Wilms’ tumor.
Zhuo Liu, Feng He, Shengrong OuYang, Yuanyuan Li, Feifei Ma, Huibo Chang, Dingding Cao, Jianxin Wu   +7 more
doaj   +1 more source

Clinicopathological Characteristics and Outcomes of Genitourinary Rhabdomyosarcoma in Two Girls

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Rhabdomyosarcoma (RMS) is a soft tissue neoplasm accounting for about 8% of solid tumors in children. There are mainly four histologic subtypes of RMS: embryonal, alveolar, spindle cell/sclerosing, and pleomorphic. The genitourinary tract is the second most affected primary site of RMS. Genitourinary RMS is more common in young boys than girls.
George Evele, Francine Kouya, George Ngock, Richard Bardin   +3 more
wiley   +1 more source

Rare cases of a second recurrence of nephroblastoma with MLLT1 gene mutation: case report and literature review

Frontiers in Oncology
Nephroblastoma or Wilms tumor is the most common tumor of the urinary system in childhood. The survival rate can reach more than 90% after multidisciplinary treatment, but there is still a certain recurrence rate.
Yiling Dai, Yiling Dai, Yiling Dai, Xin Chen, Xin Chen, Xin Chen, Xin Chen, Guoqian He, Guoqian He, Guoqian He, Ju Gao, Ju Gao, Ju Gao, Xia Guo, Xia Guo, Xia Guo, Xia Guo   +16 more
doaj   +1 more source

Significant haematuria caused by a pseudo-aneurysm in nephroblastoma

Journal of Pediatric Surgery Case Reports, 2019
A 7-year-old boy presented with a nephroblastoma, frank haematuria and hypovolemic shock. The haemorrhage was controlled with embolization of the right renal artery and followed by a nephrectomy.
Jaques van Heerden, Hansraj Mangray, Fernando Ghimenton, Deneys Reitz   +3 more
doaj   +1 more source

Reninoma: An Occult Etiology of Hypertension Requiring Repeated Diagnostic Evaluation and Managed by Tumor Enucleation: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Reninoma may be undetectable on initial imaging, and repeat diagnostic evaluation is essential when biochemical suspicion persists. Intraoperative ultrasonography can enable precise localization, allowing minimally invasive tumor enucleation instead of partial or radical nephrectomy in appropriately selected patients.
Mai Nguyen Thi Ngoc, Huong Nguyen Thi Thanh, Linh Nguyen Phan Nhat, Huy Nguyen The Nam   +3 more
wiley   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Adult Nephroblastoma with Predominant Epithelial Component: A Differential Diagnostic Candidate of Papillary Renal Cell Carcinoma and Metanephric Adenoma—Report of Three Cases

Case Reports in Pathology, 2013
Although nephroblastoma is the commonest renal tumor of childhood, it is rare in adults. In cases of predominantly epithelial type occurring in adulthood, it might be difficult to distinguish it from papillary renal cell carcinoma and metanephric adenoma.
Shiho Watanabe, Hiroshi Naganuma, Michio Shimizu, Satoshi Ota, Shin-ichi Murata, Naoki Nihei, Jun Matsushima, Shuji Mikami, Naoto Kuroda, Yoji Nagashima, Yukio Nakatani   +10 more
doaj   +1 more source