Results 31 to 40 of about 14,084 (155)
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
A big Wilms tumor in a 14-months-old boy
Journal of Education, Health and Sport, 2019 Introduction. Wilms tumor (nephroblastoma) is a malignant neoplasm located in a kidney. It is typical for children and it occurs almost exclusively in a childhood. Purpose of work, material and methods. The aim of the study is presentation of symptoms,
Agnieszka Wójtowicz +3 more
doaj +3 more sources
Clinical Genetics, EarlyView.This study expands the clinical spectrum of SMARCA4 by describing a novel phenotype in three unrelated individuals with truncating variants. Distinct from Coffin–Siris syndrome and rhabdoid tumor predisposition, this new association is characterized by ocular malformations, specifically microphthalmia and coloboma.
Bertrand Chesneau +7 more
wiley +1 more source
Veterinary Record Open, Volume 13, Issue 1, June 2026.Abstract Background Animal cancer registry data are important for monitoring animal health, for prevention and research in veterinary medicine, and for comparative oncology. Since people and animals share the same environment and are exposed to many common risk factors, cancer patterns in animals may have a sentinel function for human health.
Claudio Trentin +10 more
wiley +1 more source
Nephroblastoma with Mucus-Producing and Argentaffin Cells in a Pig [PDF]
Pakistan Veterinary Journal, 2014 Nephroblastoma is the most common primary renal neoplasm of swine and man. This report describes a swine nephroblastoma localized at the caudal pole of the left kidney, extending to the renal hilum which, on light microscopy, showed unusual mucus ...
Barbara Brunetti, B. Bacci and G. Sarli
doaj
Pediatric Blood &Cancer, Volume 73, Issue 3, March 2026.ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale +6 more
wiley +1 more source
Pediatric Blood &Cancer, Volume 73, Issue 3, March 2026.ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga +56 more
wiley +1 more source
Cystic poorly differentiated nephroblastoma: A case report and review of literature
African Journal of Urology, 2014 Background: Cystic poorly differentiated nephroblastoma (CPDN) is a rare variant of nephroblastoma which follows a benign clinical course. Case diagnosis/treatment: In this report, we document a case of CPDN in a 2 year old boy who presented with ...
M.O. Odubanjo +6 more
doaj +1 more source
Frontiers in Oncology, 2023 BackgroundNephron sparing nephrectomy may not reduce the prognosis of nephroblastoma in the absence of involvement of the renal capsule, sinus vessels, and lymph nodes, However, there is no accurate preoperative noninvasive evaluation method at present ...
Xiao-Hui Ma +9 more
doaj +1 more source
Prenatal Diagnosis of Renal Anomalies Associated With a Novel Causative Variant in RAP1B Gene
Clinical Case Reports, Volume 14, Issue 3, March 2026.A case of prenatal renal cystic disease and unilateral renal agenesis is reported. Molecular investigations including TRIO next‐generation sequencing analysis using the Clinical exome sequencing protocol identified the c.179G>T, p.(Gly60Val) “de novo” variant in a heterozygous state in the RAP1B gene.
Adalgisa Cordisco +5 more
wiley +1 more source