Results 41 to 50 of about 18,165 (198)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga +56 more
wiley +1 more source
A big Wilms tumor in a 14-months-old boy
Journal of Education, Health and Sport, 2019 Introduction. Wilms tumor (nephroblastoma) is a malignant neoplasm located in a kidney. It is typical for children and it occurs almost exclusively in a childhood. Purpose of work, material and methods. The aim of the study is presentation of symptoms,
Agnieszka Wójtowicz +3 more
doaj +3 more sources
Intuitive querying of e-Health data repositories [PDF]
, 2005 At the centre of the Clinical e-Science Framework (CLEF) project is a repository of well organised, detailed clinical histories, encoded as data that will be available for use in clinical care and in-silico medical experiments.
Hallett, Catalina +2 more
core +2 more sources
A Population‐Based Assessment of Cancer Risk in Children With VACTERL
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cancer risk in children with VACTERL, a nonrandom co‐occurrence of ≥ 3 defects (vertebral, anal, cardiac, tracheoesophogeal fistula, renal, and limb), remains unclear. We evaluated this association in a population‐based study. We analyzed data from the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Study, a US registry linkage ...
Ji Yun Tark +15 more
wiley +1 more source
KIT , PDGFRα and EGFR analysis in nephroblastoma [PDF]
, 2018 Nephroblastoma prognosis has dramatically improved, but an unfavourable prognostic subgroup warrants development of novel therapeutic strategies. Selective KIT, PDGFRα and epidermal growth factor receptor (EGFR) tyrosine kinase inhibition evolved as ...
Aslanidis, Charalampos +15 more
core
Bilateral Wilms tumour: a review of clinical and molecular features [PDF]
, 2017 Wilms tumour (WT) is the most common paediatric kidney cancer and affects approximately one in 10 000 children. The tumour is associated with undifferentiated embryonic lesions called nephrogenic rests (NRs) or, when diffuse, nephroblastomatosis. WT or
Bergeron, C +3 more
core +1 more source
EGR1 Nuclear Condensates Promote Renal Cyst Development in Polycystic Kidney Disease
Exploration, EarlyView.ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is marked by aberrant cell proliferation driven by cAMP‐PKA and MAPK signaling pathways. EGR1, a transcription factor directly activated by the above two pathways, is critical in the over‐proliferation of tumor cells, which share similarities with cystic epithelial cells in ADPKD. This study
Chaoqun Ren +15 more
wiley +1 more source
MIB-1 (KI-67) proliferation index and cyclin-dependent kinase inhibitor p27(Kip1) protein expression in nephroblastoma [PDF]
, 2004 PURPOSE: A number of studies have indicated that the tumor proliferation marker MIB-1 and cell cycle inhibitor p27(Kip1) expression are of prognostic importance in a variety of cancers. The present study was performed to evaluate the
Al-Doray, A.A. +7 more
core
Neuroblastoma and nephroblastoma: a radiological review. [PDF]
, 2015 Neuroblastoma (NBL) is the most common extra-cranial tumour in childhood. It can present as an abdominal mass, but is usually metastatic at diagnosis so the symptomatology can be varied.
Dumba, Maureen +2 more
core +2 more sources
Nephroblastoma with Mucus-Producing and Argentaffin Cells in a Pig [PDF]
Pakistan Veterinary Journal, 2014 Nephroblastoma is the most common primary renal neoplasm of swine and man. This report describes a swine nephroblastoma localized at the caudal pole of the left kidney, extending to the renal hilum which, on light microscopy, showed unusual mucus ...
Barbara Brunetti, B. Bacci and G. Sarli
doaj