Results 71 to 80 of about 13,710 (218)

Opening closed inward rectifier potassium channel doors

British Journal of Pharmacology, Volume 183, Issue 10, Page 2197-2218, May 2026.
Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger, Fabian Kaiser, Marcel A. G. van der Heyden, Saïd Bendahhou   +3 more
wiley   +1 more source

Nephrocalcinosis in very low birth weight infants

Saudi Journal of Kidney Diseases and Transplantation, 2010
To determine the incidence and risk factors of nephrocalcinosis in preterm infants, we studied in a prospectively 64 preterm infants of birth weight :5 1500 g from February 2006 to November 2007. Data were collected on gestation, birth weight, gender and
Nasseri Fatemeh, Azhir Afshin, Rahmanian Shiva, Iranpour Ramin, Adibi Atoosa   +4 more
doaj  

A case of nephrocalcinosis in a 7‐month‐old with congenital hypothyroidism: Insights from targeted exome sequencing

Pediatric Discovery
Nephrocalcinosis is a complex disease with a multitude of triggering factors. An association with congenital hypothyroidism has been described in the literature, but the mechanisms leading to its development remain unclear. A 7‐month‐old infant presented
Omar Zgheib, Lina Quteineh, Paloma Parvex, Caterina Marconi, Valerie Schwitzgebel, Massimiliano Bertacchi   +5 more
doaj   +1 more source

Antenatal Bartter Syndrome as a Rare Cause of Severe Polyhydramnios: A Case Report and Review of the Literature

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Severe polyhydramnios occurs in 1%–2% of pregnancies and may be associated with maternal diabetes, fetal structural anomalies, genetic disorders, or remain idiopathic. Among the rare etiologies is Bartter syndrome, a renal tubular defect causing impaired salt reabsorption.
Fatemeh Shariati nia, Atefe Hashemi, Shaghayegh Moradi Alamdarloo, Maryam Kasraeian, Dorna Derakhshan, Hamide Barzegar   +5 more
wiley   +1 more source

Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]

, 2018
Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco, Bonci, Enea, Celani, Camilla, Marrucci, Oriana, Pedetti, Valeria, Schiavetti, Amalia, Varrasso, Giulia   +6 more
core   +1 more source

Nephrocalcinosis: the latest reports on risk factors – a review

Pediatria Polska
This review synthesizes recent discoveries in the risk factors of nephrocalcinosis, with a particular focus on novel findings. Nephrocalcinosis, characterized by the deposition of calcium salts in the renal parenchyma, is linked to a variety of genetic ...
Tomasz Dudzik, Łucja Dudzik, Igor Domański, Aleksandra Kozieł, Paulina Wójcik, Natalia Kuderska   +5 more
doaj   +1 more source

A secretory kinase complex regulates extracellular protein phosphorylation. [PDF]

, 2015
Although numerous extracellular phosphoproteins have been identified, the protein kinases within the secretory pathway have only recently been discovered, and their regulation is virtually unexplored.
Cui, Jixin, Dixon, Jack E, Rahdar, Meghdad, Tagliabracci, Vincent S, Wen, Jianzhong, Xiao, Junyu   +5 more
core   +2 more sources

Severe Hypertension and Hematologic Abnormalities in Pseudoxanthoma Elasticum: A Pediatric Case Report

The Journal of Clinical Hypertension, Volume 28, Issue 4, April 2026.
ABSTRACT Pseudoxanthoma elasticum (PXE) is a rare autosomal recessive disorder caused by pathogenic variants in ABCC6, leading to progressive calcification of elastic fibers. Although PXE typically presents in adolescence with dermatologic or ocular manifestations, early vascular involvement, including pediatric hypertension, is increasingly recognized.
Hana Flogelova, Dagmar Pospisilova, Lenka Bakaj‐Zbrozkova, Lucie Sochorcova, Jirina Manakova, Eva Kriegova, Pavla Koralkova, Katarina Hlusickova Kapralova, Monika Horvathova   +8 more
wiley   +1 more source

Fatal Hemorrhagic Septicemia in Common Guitarfish (Rhinobatos rhinobatos) Caused by Photobacterium damselae Subsp. damselae in a Controlled Environment

Journal of Fish Diseases, Volume 49, Issue 4, April 2026.
ABSTRACT Elasmobranchs, including sharks and rays, are commonly housed in public aquariums due to their ecological significance and educational value. The common guitarfish (Rhinobatos rhinobatos), currently listed as ‘Critically Endangered’ by the IUCN, is particularly susceptible to population declines due to overfishing and bycatch.
Giorgia Bignami, Teresa Pirollo, Perla Tedesco, Monica Caffara, Maria Letizia Fioravanti, Elena Campesi, Cristiano Da Rugna, Stefano Gridelli, Francesco Quaglio, Andrea Gustinelli   +9 more
wiley   +1 more source

Hydrochlorothiazide in CLDN16 mutation [PDF]

, 2017
Background. Hydrochlorothiazide (HCT) is applied in the therapy of familial hypomagnesaemia with hypercalciuria and nephrocalcinosis (FHHNC) caused by claudin-16 (CLDN16) mutation. However, the short-term efficacy of HCT to reduce hypercalciuria in FHHNC
Dötsch, Jörg, Gravou-Apostolatou, Chara, Konrad, Martin, Plank, Christian, Rascher, Wolfgang, Stöhr, Wolfgang, Zimmermann, Bettina   +6 more
core