Results 121 to 130 of about 23,590 (248)

Unravelling drug-induced hypertension: Molecular mechanisms of aldosterone-independent mineralocorticoid receptor activation by posaconazole [PDF]

, 2018
Drug-induced hypertension offers the opportunity to further understand pathways involved in the regulation of blood pressure. Posaconazole is an antifungal agent known to induce hypertension and hypokalaemia.
Ortiz, Alberto, Sánchez-Niño, María Dolores   +1 more
core   +2 more sources

Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus.

JCI Insight, 2017
Psychiatric patients treated with lithium (Li+) may develop nephrogenic diabetes insipidus (NDI). Although the etiology of Li+-induced NDI (Li-NDI) is poorly understood, it occurs partially due to reduced aquaporin-2 (AQP2) expression in the kidney ...
S. Poulsen, T. B. Kristensen, H. Brooks, D. Kohan, T. Rieg, R. Fenton   +5 more
semanticscholar   +1 more source

Feeding difficulties in infancy as an early symptom of different forms of diabetes insipidus – a series of cases

Pediatria Polska
Feeding disorders of infancy are common in paediatric practice. Among rare causes of this disturbance is diabetes insipidus (DI), which is a clinical syndrome characterized by polyuria, polydypsia and dehydration with hypernatraemia.
Katarzyna Anna Banasiak, Małgorzata Barbara Stańczyk, Elżbieta Szczepanik, Katarzyna Monika Krawiranda, Anita Janus, Kacper Piotr Kościelny, Marcin Tkaczyk   +6 more
doaj   +1 more source

Type 1 Bartter syndrome presenting as primary diabetes insipidus: a rare Case Report with 8-year follow-up

Frontiers in Genetics
Type 1 Bartter syndrome (BS), a rare autosomal recessive salt-losing tubulopathy, classically presents with hyponatremia, hypochloremia, hypokalemic alkalosis, and hyperreninemic hyperaldosteronism. We report a male patient with the atypical presentation
Huijuan Lu, Shaojun Liu, Jia Sun, Lijun Mou   +3 more
doaj   +1 more source

Protein quality control: the who's who, the where's and therapeutic escapes [PDF]

, 2018
In cells the quality of newly synthesized proteins is monitored in regard to proper folding and correct assembly in the early secretory pathway, the cytosol and the nucleoplasm.
Fan, Jingyu, Gaplovska-Kysela, Katarina, Guhl, Bruno, Hirano, Kiyoko, Le Fourn, Valerie, Roth, Jürgen, Santimaria, Roger, Torossi, Tania, Yam, Gary, Ziak, Martin, Zuber, Christian   +10 more
core  

Functional variation in the arginine vasopressin 2 receptor as a modifier of human plasma von Willebrand factor levels\ud [PDF]

, 2010
Objectives: Stimulation of arginine vasopressin 2 receptor (V2R) with arginine vasopressin (AVP) results in a rise in von Willebrand factor (VWF) and factor VIII plasma levels.
Bertina, R.M., Deen, P.M.T., Doggen, C.J.M., Eikenboom, J.C.J., Hansen, J.L., Nossent, A.Y., Robben, J.H., Rosendaal, F.R., Sheikh, S.P., Vos, H.L.   +9 more
core   +11 more sources

New insights into the transcriptional regulation of aquaporin-2 and the treatment of X-linked hereditary nephrogenic diabetes insipidus

Kidney Research and Clinical Practice, 2019
The kidney collecting duct (CD) is a tubular segment of the kidney where the osmolality and final flow rate of urine are established, enabling urine concentration and body water homeostasis.
Hyun Jun Jung, T. Kwon
semanticscholar   +1 more source

Síndrome poliuria-polidipsia : ¿Como abordaría el diagnóstico? [PDF]

, 1989
El síndrome poliuria-polidipsia (PU/PD) es una entidad clínica que se presenta como signo predominante de numerosos procesos del perro y del gato. Tras un recuerdo fisiológico de los factores reguladores de la homeostasis del agua, presentamos las ...
Aceña Fabián, M. Carmen, Aznar Chicote, J., Díez González, R., García-Belenguer, Sylvia, Marca Andrés, Mª C., Verde Arribas, Mª T.   +5 more
core  

Nephrogenic diabetes insipidus associated with a new mutation in the AVPR2 gene

Ожирение и метаболизм
Diabetes insipidus (DI) is an orphan disease clinically characterized by profound thirst and the excretion of large volumes of dilute urine. Nephrogenic diabetes insipidus (NDI) is characterized by resistance to the action of antidiuretic hormone (ADH ...
Y. A. Aleynikova, M. S. Berlovich, E. A. Pigarova, L. K. Dzeranova, M. S. Pankratova   +4 more
doaj   +1 more source

Tubulointerstitial nephritis in primary Sjögren syndrome: clinical manifestations and response to treatment [PDF]

, 2016
BACKGROUND: Primary Sjögren syndrome (pSS) is a common autoimmune condition which primarily affects epithelial tissue, often including the kidney causing either tubulointerstitial nephritis (TIN) or more rarely, an immune complex related ...
Ciurtin, C, Evans, RD, Laing, CM, Walsh, SB   +3 more
core