Results 21 to 30 of about 23,590 (248)

Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus

Nature Communications, 2017
Nrf2 regulates oxidative and electrophilic stress responses by modulating the expression of enzymes involved in detoxification pathways. Here Suzukiet al.
Takafumi Suzuki, Shiori Seki, Keiichiro Hiramoto, Eriko Naganuma, Eri H. Kobayashi, Ayaka Yamaoka, Liam Baird, Nobuyuki Takahashi, Hiroshi Sato, Masayuki Yamamoto   +9 more
doaj   +2 more sources

Nephrogenic Diabetes Insipidus

Apollo Medicine, 2007
Congenital nephrogenic diabetes insipidus is a rare disorder of resistance to Anti Diuretic Hormone (ADH), characterized by polyuria, polydipsia, low urine osmolality and high serum osmolality. Diagnosis is established by measuring serum and urine osmolality, water deprivation test and vasopressin challenge test. This report describes a 4½-year-old boy
A. Sindhwani, D. Singhal, N. Jerath
doaj   +2 more sources

AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus

Nature Communications, 2018
Patients suffering from congenital nephrogenic diabetes insipidus (NDI) fail to concentrate urine due to mutations in vasopressin type 2 receptor (V2R). Here Ando et al.
Fumiaki Ando, Shuichi Mori, Naofumi Yui, Tetsuji Morimoto, Naohiro Nomura, Eisei Sohara, Tatemitsu Rai, Sei Sasaki, Yoshiaki Kondo, Hiroyuki Kagechika, Shinichi Uchida   +10 more
doaj   +2 more sources

A case of ifosfamide-induced acute kidney injury, Fanconi syndrome, and nephrogenic diabetes insipidus. [PDF]

CEN Case Rep, 2023
Hoang S, Pujar T, Bellorin-Font E, Edwards JC, Miyata KN.   +4 more
europepmc   +2 more sources

Nephrogenic Diabetes Insipidus Affecting Three Males in Two Generations—Case Report and Review of the Literature [PDF]

Children
Background: Nephrogenic diabetes insipidus (NDI) is defined as the inability of the kidney to concentrate urine owing to the insensitivity of the distal nephron to the antidiuretic hormone, arginine vasopressin.
Ramona Stroescu, Adela Chiriţă-Emandi, Maria Puiu, Flavia Chisavu, Ruxandra Steflea, Gabriela Doroş, Mihai Gafencu   +6 more
doaj   +2 more sources

Partial central diabetes insipidus during lithium use: A case report and literature review

PCN Reports
Background Nephrogenic diabetes insipidus (NDI) is a well‐known adverse effect of lithium, which occurs in approximately 20%–40% of long‐term lithium users.
Mizue Ichinose, Yuri Kobayashi, Yuhei Suzuki, Yoichiro Hirata, Masayuki Goto, Sho Horikoshi, Keiko Kanno‐Nozaki, Kenya Watanabe, Satoshi Takeuchi, Itaru Miura   +9 more
doaj   +2 more sources

Nephrogenic Diabetes Insipidus [PDF]

Pediatric Clinics of North America, 2019
Body fluid homeostasis is essential for normal life. In the maintenance of water balance, the most important factor and regulated process is the excretory function of the kidneys. The kidneys are capable to compensate not only the daily fluctuations of water intake but also the consequences of fluid loss (respiration, perspiration, sweating, hemorrhage)
András, Balla, László, Hunyady
openaire   +4 more sources

Characterization of three vasopressin receptor 2 variants: an apparent polymorphism (V266A) and two loss-of-function mutations (R181C and M311V). [PDF]

, 2013
Arginine vasopressin (AVP) is released from the posterior pituitary and controls water homeostasis. AVP binding to vasopressin V2 receptors (V2Rs) located on kidney collecting duct epithelial cells triggers activation of Gs proteins, leading to increased
Armstrong, Stephen P, Ayoub, Mohammed Akli, Feldman, Brian J, Pfleger, Kevin DG, Seeber, Ruth M   +4 more
core   +9 more sources

Hereditary tubulopathies accompanying polyuia

Regulatory Mechanisms in Biosystems, 2021
Tubulopathies are a group of heterogeneous diseases that are manifested in the malfunction of the renal tubules. This review addresses tubulopathies associated with polyuria syndrome, namely renal glucosuria syndrome, nephrogenic diabetes insipidus and ...
M. O. Ryznychuk, V. P. Pishak, N. V. Bacyuk-Ponych, O. V. Pishak   +3 more
doaj   +1 more source

Bioinformatics‐guided disproportionality analysis of sevoflurane‐induced nephrogenic diabetes insipidus using the FDA Adverse Event Reporting System database

British Journal of Clinical Pharmacology, 2023
Sevoflurane is an ether‐based inhalational anaesthetic that induces and maintains general anaesthesia. Our study aimed to detect sevoflurane‐induced nephrogenic diabetes insipidus using data mining algorithms (DMAs) and molecular docking.
Akhil T. Jacob, Ankitha Hari Kumar, Gayethri Halivana, Lipin Lukose, Gouri Nair, Viswam Subeesh   +5 more
semanticscholar   +1 more source